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Wang-shu Liu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Ling-yan Hua Department of Ophthalmology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Su-xiang Zhu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Feng Xu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xue-qin Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Chun-feng Lu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jian-bin Su Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Feng Qi Emergency Intensive Care Unit, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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self-report questionnaires with the assistance of an experienced clinician. Assessment of serum SDF-1 level Fasting blood samples were collected the morning after enrollment for the measurement of laboratory parameters and serum SDF-1 levels

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0629
Volume/Issue:
Volume 11: Issue 4
Open access
Natalio García-Honduvilla Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain

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Alberto Cifuentes Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain

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Miguel A Ortega Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain

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Marta Pastor Biopraxis Research AIE, Álava, Spain

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Garazi Gainza Biopraxis Research AIE, Álava, Spain

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Eusebio Gainza Biopraxis Research AIE, Álava, Spain

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Julia Buján Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain

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Melchor Álvarez-Mon Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Immune System Diseases-Rheumatology and Oncology Service, University Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain

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responses, including clotting, platelet activation, inflammatory cell infiltration, re-epithelialization, granulation tissue formation, ECM deposition, wound contraction and tissue maturation ( 1 ). The wound healing process can become impaired due to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0117
Volume/Issue:
Volume 7: Issue 4
Open access
Marc Blondon Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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Emmanuel Biver Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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Olivia Braillard Division of Primary Care Medicine, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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Marc Righini Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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Pierre Fontana Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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Alessandro Casini Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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) Hemoglobin, g/L 138.7 (16.5) b Platelets, G/L 287.8 (66.1) b Prothrombin time, % c 92.3 (8.6) aPTT, s c 30.0 (3.2) Fibrinogen, g/L c 3.1 (0.7) a 1 and b 7 missing values; c Normal ranges: Prothrombin time >70

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0429
Volume/Issue:
Volume 8: Issue 11
Open access
Lukas Ochsner Ridder Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark

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Agnethe Berglund Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics and Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

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Kirstine Stochholm Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark

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Simon Chang Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark

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Claus H Gravholt Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark

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tomography shows reduced bone parameters compared to controls ( 13 ). One study found vertebral fractures were more likely in KS patients diagnosed after the age of 21 compared to those diagnosed before the age of 21, regardless of BMD ( 14 ). Di Nisio et al

Article Type:
Review Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-23-0024
Volume/Issue:
Volume 12: Issue 5
Open access
Yusaku Mori Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Hiroyuki Shimizu Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan
Maebashi Hirosegawa Clinic, Maebashi, Gunma, Japan

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Hideki Kushima Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Tomomi Saito Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Munenori Hiromura Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Michishige Terasaki Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Masakazu Koshibu Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Hirokazu Ohtaki Department of Anatomy, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Tsutomu Hirano Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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smooth muscle cells (VSMCs). Materials and methods Chemical agents Human nesfatin-1 was purchased from Sigma-Aldrich Japan (Product ID: SRP3291; Tokyo, Japan). Platelet-derived growth factor (PDGF)-BB was obtained from Wako (Osaka, Japan

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0120
Volume/Issue:
Volume 8: Issue 5
Open access
Chun-feng Lu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xiao-qin Ge Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Yan Wang Department of Geriatrics, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jian-bin Su Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xue-qin Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Dong-mei Zhang Clinical Medicine Research Center, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Feng Xu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Wang-shu Liu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Min Su Department of Endocrinology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, China

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radicals, inhibiting platelet activation and maintaining cholesterol homeostasis ( 12 , 13 ). Thus, elevated serum ADA levels in T2D may be associated with myocardial ischemia. Coincidentally, Yu et al. have found that serum ADA levels are associated

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0199
Volume/Issue:
Volume 10: Issue 8
Open access
David Koeckerling Medical Sciences Division, University of Oxford, Oxford, UK

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Jeremy W Tomlinson Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, UK

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Jeremy F Cobbold Oxford Liver Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK

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longest follow-up studies available (mean follow-up 26.4 years) supports the notion that NAFLD confers increased all-cause mortality (HR 1.29) with advanced fibrosis being the only histological parameter to predict mortality ( 14 ). Hepatic fibrosis in

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0174
Volume/Issue:
Volume 9: Issue 7
Open access
Erika Biegelmeyer Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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Iury Scanagata Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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Laura Alves Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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Murilo Reveilleau Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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Fernando Pereira Schwengber Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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Simone Magagnin Wajner Internal Medicine Division, Hospital de Clínicas de Porto Alegre, Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul

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.000  Platelets, median (IQR), 1000 cells/mm 3 249 (177–319) 266 (191–367) 228 (167–295) 0.117  C reactive protein, median (IQR), mg/L 40.1 (9.7–104.8) 56.4 (17.8–147.1) 29.1 (5.4–84.5) 0.000  Creatinine, median (IQR), mg/dL 0.98 (0

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0080
Volume/Issue:
Volume 10: Issue 8
Open access
Mette Bøgehave Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Dorte Glintborg Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark

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Jørgen Brodersen Gram Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Else-Marie Bladbjerg Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Marianne Skovsager Andersen Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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Johannes Jakobsen Sidelmann Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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antifibrinolytic parameters associated with its deficiency in an orchidectiomized rat model . Platelets 2019 30 624 – 630 . ( https://doi.org/10.1080/09537104.2018.1499886 ) 28 Matschiner JT Willingham AK . Influence of sex hormones on vitamin K deficiency

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0455
Volume/Issue:
Volume 12: Issue 4
Open access
Tao Gao Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Rui Liu Department of Oncology. The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Chunli Li Institute of Life Sciences, Chongqing Medical University, Chongqing, China

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Xinglin Chu Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Qiao Guo Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Dazhi Ke Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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involved in complement and coagulation cascade reaction, platelet activation, histidine metabolism, vitamin metabolism and absorption, fat digestion and absorption, sphingolipid metabolism, cholesterol metabolism, and other pathways ( Fig. 2 ). Basic

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0172
Volume/Issue:
Volume 12: Issue 12
Open access