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34 1087 – 1093 . ( https://doi.org/10.1007/s10815-017-0953-z ) 10.1007/s10815-017-0953-z 26 Layman LC Amde S Cohen DP Jin M Xie J. The Finnish follicle-stimulating hormone receptor gene mutation is rare in North American women with 46,XX ovarian
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Department of Gynecology and Obstetrics, Division of Genetic Epidemiology, Vitateq Biotechnology GmbH, University of Duisburg-Essen, D-45122 Essen, Germany
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confirmed, when two of the following three diagnostic criteria are present: i) hyperandrogenism, ii) polycystic ovaries with ≥12 sonographically measured small follicles with a diameter between 2 and 9 mm and/or an ovarian volume >10 ml, and iii) oligo- or
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oligomenorrhea since her first menstrual cycle at 14 years of age. At 20 years of age, she was diagnosed with polycystic ovarian syndrome (PCOS) based on her oligomenorrhea, hyperandrogenism, and micropolycystic ovaries found on pelvic ultrasound. She began
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to suppress estradiol in breast cancer patients undergoing ovarian stimulation before in vitro fertilization . Journal of Clinical Endocrinology and Metabolism 2007 92 2197 – 2200 . ( https://doi.org/10.1210/jc.2007-0247 ) 20 Mieszczak J Lowe
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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. 1 ). Figure 1 Flowchart for the diagnosis of CeH. CeH, central hypothyroidism; COS, controlled ovarian stimulation; ES, empty sella; IO, iron overload or hemochromatosis; MPHD, multiple pituitary hormone defect; MRI, magnetic resonance imaging
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phosphorylation of Sam68 has been previously implicated in cell proliferation, growth as well as in differentiation processes through different mechanisms. In fact, Sam68 phosphorylation has been reported to be stimulated by mitogenic and trophic hormones such as
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antiovarian autoantibodies localized to the granulosa cells in women with PCOS, Van Gelderen et al . suggested a role of stimulating ovarian antibodies in PCOS pathophysiology ( 18 ). However, the concept of an autoimmune etiology is not supported by other
Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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prevents inhibitors in CCs from reaching oocytes, eventually leading to meiotic resumption ( 15 , 16 ). However, this hypothesis is not fully considered. Various studies have shown that administration with follicle-stimulating hormone (FSH) in goats ( 17
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and the fatty acid concentration was measured using a fatty acid assay kit (Bio Vision). When BSA-OA was added to serum-free medium, final concentration of BSA was adjusted to 0.005%. Cell stimulation Confluent cultures were washed twice with
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gavaging the pregnant dams) was associated with changes in puberty onset, spermatogenesis, and the development of ovarian follicles up to the F3 generation. The direct, toxic endocrine-disrupting effect (i.e. a dose-response relationship) has rarely been