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Olli Helminen Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University, Hospital and University of Oulu, Oulu, Finland
Surgery Research Unit, Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland

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Tytti Pokka Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University, Hospital and University of Oulu, Oulu, Finland

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Susanna Aspholm Tampere Centre for Child Health Research, Tampere University Hospital, Tampere, Finland

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Jorma Ilonen Immunogenetics Laboratory, University of Turku, Turku, Finland
Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland

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Olli G Simell Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland

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Mikael Knip Tampere Centre for Child Health Research, Tampere University Hospital, Tampere, Finland
Pediatric Research Center, New Children’s Hospital, Helsinki University Hospital, Helsinki, Finland
Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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Riitta Veijola Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University, Hospital and University of Oulu, Oulu, Finland

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.1007/s11892-011-0223-x ) 5 Concannon P Rich SS Nepom GT . Genetics of type 1A diabetes . New England Journal of Medicine 2009 360 1646 – 1654 . ( https://doi.org/10.1056/NEJMra0808284 ) 6 Ziegler AG Rewers M Simell O Simell T Lempainen

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Maria Stelmachowska-Banaś Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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Izabella Czajka-Oraniec Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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Tsurutani N Wright K Fernandez ML Sylvester FA Vella AT Programmed cell death-1, PD-1, is dysregulated in T cells from children with new onset type 1 diabetes . PLoS ONE 2017 12 e0183887. ( https://doi.org/10.1371/journal.pone.0183887 ) 101

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Giuseppe Lisco Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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Anna De Tullio Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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Olga Disoteo Diabetology Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

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Giuseppina Piazzolla Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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Edoardo Guastamacchia Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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Carlo Sabbà Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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Vincenzo De Geronimo Unit of Endocrinology, Policlinico Morgagni CCD, Catania, Italy

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Enrico Papini Department of Endocrinology and Metabolism, Regina Apostolorum Hospital, Rome, Italy

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Vincenzo Triggiani Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

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. Adequate hydration and fiber consumption, cessation of alcoholic beverage consumption, and eating lighter and smaller meals can be useful advice ( 6 ). The association between chronic exposure to GLP-1RAs and the new onset of thyroid cancer is a growing

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Raymond J Rodgers Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia

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Jodie C Avery Robinson Research Institute, School of Public Health, The University of Adelaide, Adelaide, South Australia, Australia

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Vivienne M Moore Robinson Research Institute, School of Public Health, The University of Adelaide, Adelaide, South Australia, Australia

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Michael J Davies Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia

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Ricardo Azziz Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

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Elisabet Stener-Victorin Department of Physiology and Pharmacology Karolinska Institutet, Stockholm, Sweden

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Lisa J Moran Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia

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Sarah A Robertson Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia

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Nigel K Stepto Institute for Health and Sport, Victoria University, Melbourne, Australia

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Robert J Norman Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia
FertilitySA, Adelaide, South Australia, Australia

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Helena J Teede Monash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia

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of future type 2 diabetes risk . Diabetes Care 2011 34 2108 – 2112 . ( https://doi.org/10.2337/dc10-2201 ) 10.2337/dc10-2201 21788628 28 Capula C Chiefari E Borelli M Oliverio R Vero A Foti D Puccio L Vero R Brunetti A. A new predictive

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Huguette S Brink Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands

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Aart Jan van der Lely Department of Endocrinology, Erasmus University MC, Rotterdam, The Netherlands

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Joke van der Linden Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands

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Introduction Gestational diabetes (GD) is defined as any glucose intolerance with onset or first recognition during pregnancy. GD has a prevalence of 7% worldwide, depending on the population studied and diagnostic criteria used ( 1 ). The

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David S Mathiesen Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Jonatan I Bagger Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark

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Katrine B Hansen Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark

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Anders E Junker Steno Diabetes Center Copenhagen, Gentofte, Denmark

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Astrid Plamboeck Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Signe Harring Department of Gastroenterology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark

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Thomas Idorn Center for Cancer and Organ Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Mads Hornum Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Center for Cancer and Organ Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Jens J Holst Novartis Healthcare A/S, Copenhagen, Denmark

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Anna E Jonsson Novartis Healthcare A/S, Copenhagen, Denmark

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Torben Hansen Novartis Healthcare A/S, Copenhagen, Denmark

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Tina Vilsbøll Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Novartis Healthcare A/S, Copenhagen, Denmark
Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Asger Lund Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Filip K Knop Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark
Novartis Healthcare A/S, Copenhagen, Denmark
Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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with normal glucose tolerance and participants with type 2 diabetes from these studies were included in our analysis, and thus, participants with end-stage renal disease, maturity-onset diabetes in the young or vagotomy were excluded. Sixty

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Ruth Percik Institute of Endocrinology, Diabetes and Metabolism, Sheba Medical Centre, Ramat Gan, Israel

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Sherwin Criseno Department of Endocrinology, University Hospital Birmingham, Birmingham, UK

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Safwaan Adam Department of Endocrinology, The Christie NHS Foundation Trust, Manchester, UK

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Kate Young Royal Marsden Hospital, London, UK

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Daniel L Morganstein Department of Endocrinology, Chelsea and Westminster Hospital, London, UK
Royal Marsden Hospital, London, UK

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, according to standard diabetes approaches to these conditions ( 66 , 67 ) and a diagnostic approach to safely manage new-onset hyperglycaemia has recently been proposed ( 65 ). Summary The current CTCAE classification of endocrine irAEs is based on

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Zhaoxiang Liu Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Mingqiang Zhang Department of Respiratory and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Xiaohu Shi Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

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Wenhui Zhao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Chenxiang Cao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Lixia Jin Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Yanlei Wang Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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Jianzhong Xiao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

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autoimmune diabetes, MDSCs were able to prevent the destruction of pancreatic islets and postpone diabetes onset ( 18 ). In that study, cytokine-induced MDSCs (1 × 10 7 cells) were adoptively transferred into streptozotocin-induced mice. The adoptive

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Qiu-ming Yao Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Bin Wang Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Xiao-fei An Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Jin-an Zhang Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China

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Liumei Ding Department of Clinical Laboratory, Jinshan Hospital of Fudan University, Shanghai, China

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. Long-term complications of diabetes mellitus . New England Journal of Medicine 1993 328 1676 – 1685 . ( https://doi.org/10.1056/NEJM199306103282306 ) 10.1056/NEJM199306103282306 3 Gasser E Moutos CP Downes M Evans RM . FGF1 – a new weapon to

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Borros Arneth Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University Hospital of the Universities of Giessen and Marburg, UKGM, Justus Liebig University, Giessen, Giessen, Germany

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diabetes-associated autoantibodies in schoolchildren – the Karlsburg type 1 diabetes risk study . Annals of the New York Academy of Sciences 2004 1037 114 – 117 . ( doi:10.1196/annals.1337.017 ) 10.1196/annals.1337.017 15699502 13 Ziegler AG

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