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CXCL8 (interleukin-8 (IL-8)) were published previously ( 40 , 41 , 42 , 43 ). Primer sequences for IL1B (interleukin-1β (IL-1β)) and IL6 (interleukin-6 (IL-6)) were derived from the Harvard Primer Bank (numbers 221139821c1, 27894305c1 and
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Introduction The rising prevalence of type 2 diabetes (T2D) has posed a great threat to public health, affecting approximately 400 million people in 2017 ( 1 ). Uncontrolled and untreated T2D may lead to a variety of chronic complications ( 2
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forms of these ligands. Blocking experiments confirmed their role in suppressing T cell proliferation, interleukin-2 (IL-2) secretion, inducing hypo-responsiveness and cell death. Thus, soluble PD-1 ligands play an important role in modulating T cell
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-γ), interleukin 1 alpha (IL-1α), interleukin 1 beta (IL-1β), monocyte chemotactic protein 1 (MCP-1), interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 5 (IL-5), interleukin 6 (IL-6), interleukin 10 (IL-10), interleukin 17 alpha (IL-17α), interleukin 18 (IL
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-CoA desaturase (Scd1)/Mm00446190_m1/; peroxisome proliferator-activated receptor-gamma (Ppar-γ)/Mm00440940_m1/; interleukin-6 (Il-6)/Mm00446190_m1/; and interleukin-1beta (Il-1b)/Mm00434228_m1/. The following assays were used in human OF’s: EGR1/Hs00152928_m1
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indirect effects (due to pro-inflammatory cytokine storm) on several endocrine organs and their axes have been elucidated ( 1 , 2 , 3 ). Hypothalamic–pituitary–thyroid (HPT) axis is an essential endocrine axis that regulates energy expenditure and
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and pro-inflammatory cytokines is also induced in the endometrium of women with uRPL, such as interleukin 1beta, tumor necrosis factor alpha (TNF-alpha), interferon gamma (IFN-gamma) and transforming growth factor beta1 (TGF-beta1) ( 13 ). IL-1, TNF
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follicular cells produce interleukin-1 alpha and interleukin-6 . Clinical and Experimental Immunology 1989 77 324 – 330 . 21 Tracey KJ Cerami A . Tumor necrosis factor: a pleiotropic cytokine and therapeutic target . Annual Review of Medicine
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women ( 57 ). A further study reported an association between the dopamine D4 receptor gene ( DRD4 ) with self-reports of sexual desire and arousal in 52 men and 92 women ( 58 ). Interleukin-1beta gene ( IL1B ) has been correlated with variation in
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D Terzic IM Capkun V Peruzovic M Terzic J. FokI polymorphism, vitamin D receptor, and interleukin-1 receptor haplotypes are associated with type 1 diabetes in the dalmatian population . Journal of Molecular Diagnostics 2005 5