Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA
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Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA
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– 867 . ( doi:10.1016/j.neuroscience.2005.09.006 ) 4 Voytko ML Higgs CJ Murray R . Differential effects on visual and spatial recognition memory of a novel hormone therapy regimen of estrogen alone or combined with progesterone in older
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Faculty of Life Sciences and Medicine, School of Life Course Sciences, King’s College London, London, UK
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Quebec Heart and Lung Institute, Laval University, Quebec, Canada
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Barts and the London School of Medicine, Centre for Endocrinology, William Harvey Institute, London, UK
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK
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Obesity, Type 2 Diabetes and Immunometabolism Research Group, School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Course Sciences, King’s College London, London, UK
Division of Reproductive Health, Warwick Medical School, University of Warwick, Coventry, UK
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mitotane therapy frequently being offered glucocorticoid replacement therapy ( 2 ). Whilst the existing literature quite clearly demonstrates the impact of mitotane on steroids and hormone-binding proteins, to date, no studies have specifically related
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have achieved normal hormonal levels after multimodal treatment, active monitoring is essential to follow the effects of therapy and maintain their benefit. Furthermore, detection of persistent or recurrent disease is compromised when patients are not
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Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark
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controls. The design was a randomized crossover study. Both groups underwent a 2 month wash-out period from hormone replacement therapy (HRT) and oral contraceptive therapy (OCT) respectively. Subjects were examined at the end of each 2-month period. The
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true malabsorption from patients with poor adherence to therapy ( 85 ). Liver cirrhosis also increases the dose requirement for LT4 ( 86 , 87 ). Numerous medications alter the metabolism or excretion of thyroid hormones, and can influence circulating
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Royal Marsden Hospital, London, UK
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predominately on symptom severity at presentation is not helpful in guiding decisions about hormone replacement and continuation or discontinuation of ICPI therapy for endocrinopathies ( 2 ). Immune-related endocrinopathies do not fit into a five-tier symptoms
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-0526 ) 10.1210/jc.2007-0526 6 Pawlikowska-Haddal A . Growth hormone therapy with norditropin (somatropin) in growth hormone deficiency. Expert Opinion on Biological Therapy 2013 13 927 – 932 . ( doi:10.1517/14712598.2013.795941 ) 10
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
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Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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suggested to influence several extra-glycemic, metabolic, and endocrinological parameters, such as the sex hormone-binding globulin (SHBG). SHBG is a glycoprotein produced in the liver, which regulates the bioavailability of sex steroids for target tissues
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INSERM, UMRS 1166, Nutriomic Group 6, Paris, France
Sorbonne Université, UMRS1166, Paris, France
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transition Sex-hormone therapy (%) 20 (21.1) 16 (51.6) 4 (6.3) <0.0001 After transition Screening (%) § 90 (94.7) 30 (96.8) 60 (93.8) 1 Hypogonadism (%) 82/90 (91.1) 27/30 (90.0) 55/60 (91
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oestradiol as feminising gender-affirming hormone therapy ( 3 ). Goals of therapy are generally to increase serum oestradiol concentrations and lower serum total testosterone concentrations to achieve sex steroid concentrations in the female reference range