Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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labelled as detergents necessary for lipid digestion and absorption, but are increasingly recognised as metabolic integrators, capable of regulating glucose homeostasis, lipid metabolism and energy expenditure through nuclear receptors and the G protein
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University Clinic of Medicine, Cantonal Hospital Baselland, Liestal, Switzerland
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). Body composition was assessed with bioelectrical impedance analysis, which correlates well with dual-energy x-ray absorptiometry under standardized conditions ( 12 ). Blood sampling was initiated at least 1 h after the arrival at the research facility
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( 2 ). However, to date, the energy metabolism of fish after a GTT has barely been investigated. It is now widely acknowledged that, the energy metabolism of fish is monitored by the intracellular energy sensors ( 1 , 10 ). Indeed, several studies
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intensity between water and land trials. However, energy metabolism in the water and land trials matched, with no significant difference being observed in VO 2 . In addition, no significant differences were noted in the feeling of dyspnea after walking
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
Department of Nursing Physiotherapy and Medicine, SPORT Research Group (CTS-1024), CERNEP Research Center, University of Almería, Almería, Spain
Biomedical Research Unit, Torrecárdenas University Hospital, Almería, Spain
CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Granada, Spain
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Department of Medicine, Huddinge, Karolinska Institutet Campus Flemingsberg, Neo Building, Huddinge, Sweden
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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that could enhance energy metabolism ( 15 ). Preclinical experiments have identified two batokines that have a prominent effect on energy balance: fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) ( 16 , 17 ). FGF21, when
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA
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eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA
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eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA
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eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA
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metabolism ( 11 , 12 , 13 ); however, profiling central energy and redox metabolites presents a unique opportunity to better understand aberrant metabolism observed in this population. The aim of this study was to compare the plasma metabolic signatures of
Willem-Alexander Children’s Hospital, Department of Pediatrics, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
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energy metabolism, and neurodevelopmental disorders such as autistic behavior and obsessive-compulsive disorder. Without strict regulation of food intake, morbid obesity develops ( 5 ). In PWS, changes in appetite and weight gain over time are described
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tract, pancreas, and adipose, act to influence the physiological mechanisms controlling energy regulation, eliciting divergent actions on feeding behaviour and metabolism (1) . In humans, hormonal peptides such as glucagon-like peptide-1 (GLP1) (2
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the same absolute workload as the patients, because a priori overall energy requirements and, accordingly, metabolism ought to be identical between groups (the 0-hypotheis). Comparisons between groups working at identical relative loads would be far
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-activator 1-alpha (PGC-1α), which can stimulate mitochondrial oxidative metabolism and biosynthesis ( 4 ). Bostrom et al. found uncoupling protein-1 (UCP-1) expression in the s.c. adipose cells of transgenic mice with high PGC-1α expression increased