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). Moreover, it has been proposed that intrauterine life, as an environmental factor, is implicated in the origin of PCOS ( 8 , 9 , 10 , 11 ) and may modify the endocrine and metabolic functions of a child born to a PCOS mother independently of the genetic
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
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survivors of other childhood cancers, childhood brain tumor survivors are among those at highest risk of both cognitive and physical sequelae ( 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 ). Endocrine complications are, however, some of the most frequent
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Primary hyperparathyroidism has emerged as a prevalent endocrine disorder in clinical settings, necessitating in most cases, surgical intervention for the removal of the diseased gland. This condition is characterised by overactivity of the parathyroid glands, resulting in excessive parathyroid hormone production and subsequent disturbances in calcium homeostasis. The primary mode of management is surgical treatment, relying on the accurate localisation of the pathological parathyroid gland. Precise identification is paramount to ensuring that the surgical intervention effectively targets and removes the diseased gland, alleviating the hyperfunctioning state. However, localising the gland becomes challenging, as discrepancies between the clinical manifestation of active parathyroid and radiological identification are common. Based on our current knowledge, to date, no comprehensive review has been conducted that considers all factors collectively. This comprehensive review delves into the factors contributing to false-negative 99mTc-sestamibi scans. Our research involved an exhaustive search in the PubMed database for hyperparathyroidism, with the identified literature meticulously filtered and reviewed by the authors. The results highlighted various factors, including multiple parathyroid diseases, nodular goitre, mild disease, or the presence of an ectopic gland that causes discordance. Hence, a thorough consideration of these factors is crucial during the diagnostic workup of hyperparathyroidism. Employing intraoperative PTH assays can significantly contribute to a successful cure of the disease, thereby providing a more comprehensive approach to managing this prevalent endocrine disorder.
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many of these women are still at risk of developing cardiovascular disease ( 8 ), due to many factors such as obesity, insulin resistance, high blood pressure and fat ( 9 ), where a 7.4-fold increase in their mortality was estimated ( 10 ). In
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Society for Endocrinology (SfE). In 2016, Endocrine Connections was included in the Science Citation Index Expanded (SCIE) and expects its first impact factor in Thomson Reuters’ listing this summer! Under the late Editor-in-Chief, Jens Sandahl
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chromosome aneuploidies. In summary, I believe that Endocrine Connections is in a good place as a well-established, fully open access journal with a consistently stable impact factor which is jointly owned by and directly supporting two of the largest
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Welcome to Endocrine Connections , a new Open Access journal offering authors the highest possible visibility for their work and stimulating cross-discipline collaboration. The journal is brought to you by the European Society of Endocrinology (ESE
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Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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characteristics, corresponding to a prevalence of 3.2% ( 3 ). The postulated underlying mechanisms for increased risk involve: shortened activated partial thromboplastin time (aPTT), increased activity of factor VIII and von Willebrand factor, hyperactivity of
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publication of widely distributed and cited original articles and timely reviews on topical endocrine subjects, Endocrine Connections received its first Impact Factor in 2017. As of today as a relatively new scientific journal, I leave it well positioned in
National Hospital for Neurology and Neurosurgery, London, UK
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National Hospital for Neurology and Neurosurgery, London, UK
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defects, most commonly a bi-temporal hemianopia, are due to optic chiasmal compression Fever, neck stiffness, photophobia or reduced consciousness (similar to signs/symptoms of SAH or meningitis) may occur Precipitating factors Hypertension
