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disorders of lipid metabolism ( 1 ), mainly with increased total cholesterol (TC) and LDL-C ( 2 ) in blood. Elevated LDL-C can lead to progressive lipid accumulation, plaque formation in the arteries and increase the risk of cardiovascular disease (CVD), the
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-Albright syndrome (MAS), a sporadic genetic disease, is caused by an activating mutation of GNAS1 for the Gs alpha membrane-associated protein, mediating the TSH-induced and other hormone-induced activation of adenylyl cyclase; subclinical hyperthyroidism can be
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affecting ethnic minorities in the UK (Feb 2022) ‘throughout the life course from birth to death’ and as being ‘rooted in experiences of structural, institutional and interpersonal racism’ ( 1 ; https://www.nhsrho.org/wp-content/uploads/2022/02/RHO
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cortistatin contains sequence elements which enable its binding to two distinct receptors, Mas-related gene 2 receptor and ghrelin receptor GHS-R1a. In addition to a different tissue distribution pattern, the existence of distinct receptors suggests that some
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Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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Introduction Infertility, which is defined as the inability to conceive after 1 year of unprotected intercourse, has a global prevalence of 9% (1) . Among infertile couples, it is estimated that the cause is predominantly feminine in 38% and
