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Rong Xu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Difei Lian Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yan Xie Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Lin Mu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yali Wu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Zhilei Chen Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Baoyu Zhang Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Introduction Osteoporosis (OP) is a metabolic bone disease characterized by reduced bone mineral density (BMD) and bone mass and destruction of bone microarchitecture, leading to increased bone fragility and increased risk of fracture ( 1

Article Type:
Review Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0040
Volume/Issue:
Volume 12: Issue 11
Open access
Ali Abbara Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Sophie Clarke Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Pei Chia Eng Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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James Milburn Imperial College Healthcare NHS Trust, London, UK

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Devavrata Joshi Imperial College Healthcare NHS Trust, London, UK

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Alexander N Comninos Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Rozana Ramli Imperial College Healthcare NHS Trust, London, UK

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Amrish Mehta Imperial College Healthcare NHS Trust, London, UK

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Brynmor Jones Imperial College Healthcare NHS Trust, London, UK

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Florian Wernig Imperial College Healthcare NHS Trust, London, UK

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Ramesh Nair Imperial College Healthcare NHS Trust, London, UK

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Nigel Mendoza Imperial College Healthcare NHS Trust, London, UK

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Amir H Sam Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Emma Hatfield Imperial College Healthcare NHS Trust, London, UK

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Karim Meeran Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Waljit S Dhillo Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Niamh M Martin Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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). Relieving extrinsic compression of the optic pathways through early surgical intervention remains a subject of conjecture, as surgery carries a risk of postoperative CSF rhinorrhoea and posterior pituitary damage ( 1 , 15 , 31 ). Earlier literature argued

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0255
Volume/Issue:
Volume 7: Issue 10
Open access
Brijesh Krishnappa Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Ravikumar Shah Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Saba Samad Memon Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Chakra Diwaker Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Anurag R Lila Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Virendra A Patil Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Nalini S Shah Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Tushar R Bandgar Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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hormonal deficiencies. Though several secondary etiologies viz., autoimmune, infectious, infiltrative, neoplastic, and drug-induced forms have been described, primary autoimmune hypophysitis (PAH) remains common ( 1 ). The goals of PAH treatment include

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0311
Volume/Issue:
Volume 12: Issue 2
Open access
Nidan Qiao Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Harvard Medical School, Boston, Massachusetts, USA

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publication bias of the literature. All the statistical analyses were performed with R Studio, version 1.0.143. Results Study characteristics A total of 1104 citations were identified by our search strategy. After a detailed evaluation of these

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-17-0312
Volume/Issue:
Volume 7: Issue 1
Open access
Malgorzata Oczko-Wojciechowska Department of Genetic and Molecular Diagnostics of Cancer, M. Sklodowska-Curie Institute National Research Institute of Oncology Gliwice Branch, Gliwice, Poland

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Agnieszka Czarniecka Oncologic and Reconstructive Surgery Clinic, M. Sklodowska-Curie Institute National Research Institute of Oncology Gliwice Branch, Gliwice, Poland

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Tomasz Gawlik Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute National Research Institute of Oncology Gliwice Branch, Gliwice, Poland

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Barbara Jarzab Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute National Research Institute of Oncology Gliwice Branch, Gliwice, Poland

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Jolanta Krajewska Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute National Research Institute of Oncology Gliwice Branch, Gliwice, Poland

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identified in ALK, ATM, CSF1R, GNAS, SMARCB1 , and NOTCH1 genes. This alteration was not previously reported in metastatic MTC. Spoziello et al . detected germline p.Arg417Gln mutation in the MET gene in siblings diagnosed with MTC and other primary

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0374
Volume/Issue:
Volume 9: Issue 12
Open access
Nancy Martini Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Lucas Streckwall Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Antonio Desmond McCarthy Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Introduction In adults from Westernized societies, the arterial system is the second most mineralized site after the skeleton, and there is increasing evidence of a reciprocal regulation between the calcification of both systems ( 1 , 2 ). In

Article Type:
Review Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0305
Volume/Issue:
Volume 12: Issue 11
Open access
Christian Høst Department of Endocrinology and Internal Medicine and the Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Aarhus N, Denmark
Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Anders Bojesen Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark

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Mogens Erlandsen Section for Biostatistics, Department of Public Health, Aarhus University, Aarhus C, Denmark

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Kristian A Groth Department of Molecular Medicine, Aarhus University Hospital, Aarhus N, Denmark

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Kurt Kristensen Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Anne Grethe Jurik Department of Radiology, Aarhus University Hospital, Aarhus N, Denmark

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Niels H Birkebæk Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Claus H Gravholt Department of Endocrinology and Internal Medicine and the Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Aarhus N, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus N, Denmark

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. ( https://doi.org/10.1210/jcem.87.1.8172 ) 38 Gibb FW Homer NZ Faqehi AM Upreti R Livingstone DE McInnes KJ Andrew R Walker BR . Aromatase inhibition reduces insulin sensitivity in healthy men . Journal of Clinical Endocrinology and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0323
Volume/Issue:
Volume 8: Issue 9
Open access
Gavin P Vinson School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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Caroline H Brennan School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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Y Franck J Spangler R Maggos CE Ho A Kreek MJ . Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration . Alcoholism, Clinical and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0028
Volume/Issue:
Volume 2: Issue 3
Open access
Stefan M Constantinescu Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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Thierry Duprez Department of Radiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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Edward Fomekong Department of Neurosurgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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Christian Raftopoulos Department of Neurosurgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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Orsalia Alexopoulou Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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Dominique Maiter Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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( 1 ) (NFPAs). Even though radiological and autopsy studies find mostly small pituitary microadenomas ( 2 , 3 , 4 ) (<1 cm), recent case series revealed that more than half of PIs coming to medical attention are macroadenomas ( 5 , 6 , 7 , 8 , 9

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-23-0224
Volume/Issue:
Volume 12: Issue 12
Open access
Helene Bandsholm Leere Tallaksen Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

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Emma B Johannsen Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

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Jesper Just Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

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Mette Hansen Viuff Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark

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Claus H Gravholt Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Endocrinology, Aarhus University Hospital, Aarhus, Denmark

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Anne Skakkebæk Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark

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and 95% of the expression levels seen from Xa ( 6 , 7 ). The genes in the pseudoautosomal region 1 (PAR1) ( AKAP17A , ASMT , ASMTL , CD99 , CD99P1 , CRLF2 , CSF2RA , DHRSX , GTPBP6 , IL3RA , P2RY8,PLCXD1 , PPP2R3B , SHOX , SLC25A6 , XG

Article Type:
Review Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-23-0011
Volume/Issue:
Volume 12: Issue 9
Open access