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Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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, 23 , 24 ). Of note, the number of subjects varied between analyses owing to a lack of measurements in some cases. Serum concentrations of testosterone and sex hormone-binding globulin (SHBG) were analysed by means of liquid chromatography
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accumulation product; OGTT, oral glucose tolerance test; PCOS, polycystic ovary syndrome; SHBG, serum sex hormone–binding globulin; TG, triglycerides; VAI, visceral adiposity index. Women with PCOS had higher serum LH concentration ( P = 0.01), as
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measures, testosterone levels, sex hormone-binding globulin (SHBG), smoking, hypertension, leisure-time physical activity (LTPA), or diabetes were excluded, leaving a remainder of 641 men. Individuals with CRP >10 mg/dL were excluded in this study, in line
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, Westmead, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
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Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, New South Wales, Australia
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Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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) other biochemical markers, including serum levels of testosterone, urea, sex hormone-binding globulin (SHBG) and prostate-specific antigen (PSA). Participants were studied after an overnight fast in the Blacktown Clinical School and Research Centre
MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
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Resistin 1 (18) CVDFACTS Taiwan/2014 US, Europe/2010 230/3400 rs3745367,rs1423096/ RETN OR, 1.38 GG Sex hormone-binding globulin 2 (21, 34) WTCCC, Dundee, EFS-Y2TD, Danish, DGI, MCC, FUSION 1-2, KORA, Cambridgeshire, ADDITION-Ely, NDCCS, DeCODE, METSIM
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studies suggests that there is no inherent T2DM risk in PCOS and that, instead, it is a result of either increased BMI, of androgens, and/or of low sex hormone-binding globulin (SHBG) values ( 10 ). However, PCOS constitutes a polygenic trait and the
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KORA Study Centre, University Hospital of Augsburg, Augsburg, Augsburg, Germany
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German Centre for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Munich, Germany
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German Heart Centre Munich, Technical University of Munich, Munich, Germany
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
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German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany
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of all quantifier transitions are summarized in Supplementary Fig. A1, Supplementary Fig. A2 and Supplementary Table A1. Sex hormone-binding globulin (SHBG) concentrations were measured using an automated chemiluminescence immunoassay (Cobas e14
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metabolism and fetal development. Patients with GDM have been reported to have lower concentrations of sex hormone-binding globulin (SHBG) compared to healthy pregnant women ( 35 ). SHBG, a plasma transport protein of sex hormones, can bind to circulating sex
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Blood samples from each participant were collected at phase A, B and C, at 07:00–09:00 h, 48–72 h following the last exercise session as previously described ( 23 , 24 , 25 , 26 ). Serum concentrations of TT, sex hormone-binding globulin (SHBG) and
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Sex hormone binding globulin as a valuable biochemical marker in predicting gestational diabetes mellitus . BMC Women’s Health 2017 17 18. ( https://doi.org/10.1186/s12905-017-0373-3 ) 3 Brown J Grzeskowiak L Williamson K Downie MR