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Stefan Pilz, Armin Zittermann, Christian Trummer, Verena Theiler-Schwetz, Elisabeth Lerchbaum, Martin H Keppel, Martin R Grübler, Winfried März and Marlene Pandis

supplementation such as the Vitamin D Assessment (ViDA) Study in 5108 older individuals randomized to 2500 µg (100,000 IU) of vitamin D per month or placebo did not report on increased risk of fractures or falls ( 128 , 129 ). In line with this, a recent meta-analysis

Open access

T P McVeigh, R J Mulligan, U M McVeigh, P W Owens, N Miller, M Bell, F Sebag, C Guerin, D S Quill, J B Weidhaas, M J Kerin and A J Lowery

remained ill-defined. A recent meta-analysis has revisited the possibility of such an association and has confirmed the existence of, and quantified the increased co-occurrence of breast and differentiated thyroid cancer (DTC) ( 1 ). Both cancers occur

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S Westra, Y H M Krul-Poel, H J van Wijland, M M ter Wee, F Stam, P Lips, F Pouwer and S Simsek

-to-moderate positive effect of short-term vitamin D supplementation on HRQOL in diseased people ( 28 ). However, no meta-analysis could be done due to the great heterogeneity in study samples, dose and type of vitamin D supplementation and the variation of HRQOL

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Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber and Sven O Skouby

endothelial dysfunction, which is associated with an increased risk of cardiovascular disease (CVD) ( 4 ). PCOS is associated with both CVD and venous thromboembolism (VTE). A recent meta-analysis found an odds ratio of 1.44 (1.13–1.84) for coronary heart

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M Jensterle, A Podbregar, K Goricar, N Gregoric and A Janez

meta-analysis that was limited to small studies with short-term follow-up and heterogeneous study designs ( 3 , 20 ). Its impact was generally related to the magnitude of WR. Five per cent of weight loss with LSM was associated with the 2 mmol

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Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź and Aldona Kowalska

introduction of the new nomenclature, it appears that the initial calculations were overestimated ( 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). According to the meta-analysis conducted by Bychkov et al . (25 studies, 46

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Alessandra Gambineri and Carla Pelusi

). Observational cross-sectional studies performed on PCOS and included by Moran et al. in a meta-analysis estimate that the odds of T2DM are four times as high for women with PCOS compared with controls ( 12 ). A subgroup matched for BMI confirmed that the odds

Open access

Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond and Naftali Stern

waist circumference ( 12 ). A meta-analysis of more than ten prospective studies has demonstrated that women with SHBG levels higher than 60 nmol/L had 80% lower risk of type 2 diabetes ( 7 ). Men with SHBG higher than 28.3 nmol/L had a 52% smaller risk

Open access

Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden and Rodney J Scott

cancer cases and 7771 controls ( 18 ). A meta-analysis conducted recently on the effect of this repeat on the risk of developing breast cancer (which included 11 studies of various ethnicity groups with a total of 7047 cases and 12,096 controls) reported

Open access

Kristin Ottarsdottir, Margareta Hellgren, David Bock, Anna G Nilsson and Bledar Daka

different cohorts including men and women, respectively, suggesting a causal effect. The mechanism behind the association between SHGB and type 2 diabetes is not fully understood, but may be mediated through insulin resistance ( 5 ). In a meta-analysis