Search Results

You are looking at 31 - 40 of 382 items for :

Clear All
T L C Wolters Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by T L C Wolters in
Google Scholar
PubMed
Close
,
C D C C van der Heijden Division of Experimental Internal Medicine, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Division of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by C D C C van der Heijden in
Google Scholar
PubMed
Close
,
N van Leeuwen Department of Physiology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by N van Leeuwen in
Google Scholar
PubMed
Close
,
B T P Hijmans-Kersten Department of Physiology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by B T P Hijmans-Kersten in
Google Scholar
PubMed
Close
,
M G Netea Division of Experimental Internal Medicine, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by M G Netea in
Google Scholar
PubMed
Close
,
J W A Smit Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by J W A Smit in
Google Scholar
PubMed
Close
,
D H J Thijssen Department of Physiology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK

Search for other papers by D H J Thijssen in
Google Scholar
PubMed
Close
,
A R M M Hermus Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by A R M M Hermus in
Google Scholar
PubMed
Close
,
N P Riksen Division of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by N P Riksen in
Google Scholar
PubMed
Close
, and
R T Netea-Maier Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Search for other papers by R T Netea-Maier in
Google Scholar
PubMed
Close

important driver of the initiation and progression of atherosclerosis, which is the main pathophysiological process driving CVD. Circulating immune cells invade the vasculature and induce expression of adhesion molecules and subsequent leukocyte adherence

Open access
Michaela Keuper Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

Search for other papers by Michaela Keuper in
Google Scholar
PubMed
Close

scarcity and high energy demands, such as exercise, cold exposure and immune responses. The dysregulation of fatty acid release contributes to dyslipidemia, resulting in ectopic fat deposition into various organs. Ectopic fat in turn impairs organ

Open access
Sophie Howarth Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for other papers by Sophie Howarth in
Google Scholar
PubMed
Close
,
Luca Giovanelli Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for other papers by Luca Giovanelli in
Google Scholar
PubMed
Close
,
Catherine Napier Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for other papers by Catherine Napier in
Google Scholar
PubMed
Close
, and
Simon H Pearce Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for other papers by Simon H Pearce in
Google Scholar
PubMed
Close

as type 1 diabetes, autoimmune hypothyroidism and pernicious anaemia. Complex interplay between genetic and environmental factors gives rise to immune-mediated destruction of the steroid-producing cells of the adrenal cortex. As in type 1 diabetes

Open access
J Brossaud Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

Search for other papers by J Brossaud in
Google Scholar
PubMed
Close
,
V Pallet Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

Search for other papers by V Pallet in
Google Scholar
PubMed
Close
, and
J-B Corcuff Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

Search for other papers by J-B Corcuff in
Google Scholar
PubMed
Close

childhood blindness as vitamin A and metabolites act as morphogens that modulates gene transcription during embryogenesis. In developed adults, vitamin A and metabolites play key roles in vision, immune and brain functions and tissue remodelling and

Open access
Yali Cheng Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Yali Cheng in
Google Scholar
PubMed
Close
,
Qiaoying Lv Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Qiaoying Lv in
Google Scholar
PubMed
Close
,
Bingying Xie Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Bingying Xie in
Google Scholar
PubMed
Close
,
Bingyi Yang Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Bingyi Yang in
Google Scholar
PubMed
Close
,
Weiwei Shan Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Weiwei Shan in
Google Scholar
PubMed
Close
,
Chengcheng Ning Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Chengcheng Ning in
Google Scholar
PubMed
Close
,
Bing Li Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Bing Li in
Google Scholar
PubMed
Close
,
Liying Xie Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Liying Xie in
Google Scholar
PubMed
Close
,
Chao Gu Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Chao Gu in
Google Scholar
PubMed
Close
,
Xuezhen Luo Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Xuezhen Luo in
Google Scholar
PubMed
Close
,
Xiaojun Chen Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

Search for other papers by Xiaojun Chen in
Google Scholar
PubMed
Close
, and
Qin Zhu Department of Pathology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, China

Search for other papers by Qin Zhu in
Google Scholar
PubMed
Close

group. Focusing on the top ten terms of the three treatment groups, we found that the inflammatory response, the innate immune response and cell adhesion were affected ( Fig. 2C ). We further used KEGG to analyze the signaling pathways in which these

Open access
Christos Tsatsanis Department of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Crete, Greece
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece

Search for other papers by Christos Tsatsanis in
Google Scholar
PubMed
Close
,
Angel Elenkov Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden

Search for other papers by Angel Elenkov in
Google Scholar
PubMed
Close
,
Irene Leijonhufvud Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden

Search for other papers by Irene Leijonhufvud in
Google Scholar
PubMed
Close
,
Katerina Vaporidi Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden

Search for other papers by Katerina Vaporidi in
Google Scholar
PubMed
Close
,
Åsa Tivesten Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden

Search for other papers by Åsa Tivesten in
Google Scholar
PubMed
Close
, and
Aleksander Giwercman Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden

Search for other papers by Aleksander Giwercman in
Google Scholar
PubMed
Close

Introduction Low-grade systemic inflammation is associated with multiple conditions including cardiovascular disease, metabolic disease and osteoporosis and is the result of sustained activation of immune cells. The contribution of sex and sex

Open access
Taís S Assmann Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Search for other papers by Taís S Assmann in
Google Scholar
PubMed
Close
,
Mariana Recamonde-Mendoza Institute of Informatics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Search for other papers by Mariana Recamonde-Mendoza in
Google Scholar
PubMed
Close
,
Bianca M De Souza Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Search for other papers by Bianca M De Souza in
Google Scholar
PubMed
Close
, and
Daisy Crispim Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Search for other papers by Daisy Crispim in
Google Scholar
PubMed
Close

the infiltrating immune system. T1DM development is slow, providing a potentially long window of time in which it is possible to identify and theoretically treat individuals at risk ( 2 , 3 ). The first sign of autoimmunity against beta

Open access
Anna Olsson-Brown Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
The Clatterbridge Cancer Centre, Wirral, UK

Search for other papers by Anna Olsson-Brown in
Google Scholar
PubMed
Close
,
Rosemary Lord The Clatterbridge Cancer Centre, Wirral, UK

Search for other papers by Rosemary Lord in
Google Scholar
PubMed
Close
,
Joseph Sacco The Clatterbridge Cancer Centre, Wirral, UK
Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK

Search for other papers by Joseph Sacco in
Google Scholar
PubMed
Close
,
Jonathan Wagg Roche Innovation Center, Basel, Switzerland

Search for other papers by Jonathan Wagg in
Google Scholar
PubMed
Close
,
Mark Coles Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK

Search for other papers by Mark Coles in
Google Scholar
PubMed
Close
, and
Munir Pirmohamed Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK

Search for other papers by Munir Pirmohamed in
Google Scholar
PubMed
Close

Introduction Oncological immune checkpoint inhibitors (ICI) are transforming oncological practice ( 1 , 2 , 3 ). The first ICI, ipilimumab (Yervoy®), a CTLA-4 inhibitor, was used exclusively in metastatic malignant melanoma post

Open access
Elizabeth Micks Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

Search for other papers by Elizabeth Micks in
Google Scholar
PubMed
Close
,
Greta B Raglan Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

Search for other papers by Greta B Raglan in
Google Scholar
PubMed
Close
, and
Jay Schulkin Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

Search for other papers by Jay Schulkin in
Google Scholar
PubMed
Close

related steroid receptors. Research in preterm and normal labor has highlighted the impact of progesterone on immune functioning. Bringing two worlds together Biochemists continue to elucidate the mechanisms of action of different progestins in order to

Open access
Xuechao Jiang Scientific Research Center, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Xuechao Jiang in
Google Scholar
PubMed
Close
,
Yonghui Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Yonghui Wang in
Google Scholar
PubMed
Close
,
Xiaoying Li Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Xiaoying Li in
Google Scholar
PubMed
Close
,
Leqi He Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Leqi He in
Google Scholar
PubMed
Close
,
Qian Yang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Qian Yang in
Google Scholar
PubMed
Close
,
Wei Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Wei Wang in
Google Scholar
PubMed
Close
,
Jun Liu Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Jun Liu in
Google Scholar
PubMed
Close
, and
Bingbing Zha Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

Search for other papers by Bingbing Zha in
Google Scholar
PubMed
Close

differentiation ( 9 , 10 ). There is emerging evidence that lncRNAs play crucial roles in immune regulation and autoimmunity. T lymphocytes, B lymphocytes, macrophages, dendritic cells, and NK cells all express lncRNAs, which have been shown to be involved in the

Open access