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supplementation in reducing insulin resistance and diabetic chronic inflammation ( 48 ), in improving glycemic control ( 49 ) and in changing body composition ( 50 , 51 ), whereas others showed no benefit ( 52 , 53 ). In particular, the majority of trials (meta
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per startup. Traditional pharmaceutical and high-tech companies have also joined the race to develop digital health products ( 14 ). DTx has been shown to significantly improve glycemic control and provide diabetes care independently or combined with
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. It was demonstrated that weight loss could result in various metabolic benefits, including glycemic control, blood pressure improvement, and lipid profile management ( 7 , 8 , 9 ). In patients with T2D, weight loss was associated with a reduced risk
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Froesch ER . Effect of glycemic control on serum insulin-like growth factors in diabetes mellitus . Diabetes 1984 33 790 – 793 . ( doi:10.2337/diab.33.8.790 ). 11 Amiel SA Sherwin RS Hintz RL Gertner JM Press CM Tamborlane WV . Effect of diabetes and
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-treated T2DM patients failed to prove any protective effect of tight glycemic control ( 11 ). High levels of tPA have been shown to be predictive of future T2DM independent of metabolic syndrome ( 12 , 13 ). Another study showed that tPA and PAI-1 levels
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glucose and better TIR, but not with hypoglycemia or glucose variability ( 16 ). In a smaller study in Japanese type 1 diabetes patients, stable glycemic control with minimal hypoglycemia was related to preserved C-peptide secretion ( 17 ). It is important
INSERM U1018, Université Paris Sud, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Paris, Villejuif Cedex, France
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– 1333 . ( doi:10.1001/archinte.164.12.1327 ). 4 Cukierman-Yaffe T Gerstein HC Williamson JD Lazar RM Lovato L Miller ME Coker LH Murray A Sullivan MD Marcovina SM . Relationship between baseline glycemic control and cognitive
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on drug prescriptions may lead to inadequate glycemic control ( 13 ). Importantly, individuals with newly diagnosed T2DM confront challenges including dietary choices and sick day management ( 14 ). Without adequate support from medical professionals
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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with an increase in gastric disorders such as dyspeptic pain and duodenal ulcers. A seminal study on sacubitril/valsartan treatment in heart failure patients has shown improved glycemic control in patients with both chronic heart failure and diabetes
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promote weight loss, improve glycemic control and have been demonstrated to reduce plasma levels of cholesterol, PAI-1 and hsCRP ( 25 , 26 , 27 ). Glucagonlike peptide-1 analogs have been used in PCOS in smaller trials, all demonstrating weight loss, but