Alexandra Kiess
Alexandra Kiess
Department of Pediatric Cardiology, Faculty of Medicine, Heart Center Leipzig, University of Leipzig, Strümpellstraße, Leipzig, Germany
Department of Child and Adolescent Medicine, Section of Pediatric Cardiology, University Hospital Jena, Am Klinikum, Jena, Germany
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Department of Child and Adolescent Medicine, Section of Pediatric Cardiology, University Hospital Jena, Am Klinikum, Jena, Germany
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Jessica Green
Jessica Green
Alder Hey Children's NHS Foundation Trust, Pediatric Intensive Care Unit, Eaton Road Liverpool, Great Britain
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Anja Willenberg
Anja Willenberg
Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics (ILM), University of Leipzig, Liebigstrasse, Leipzig, Germany
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Uta Ceglarek
Uta Ceglarek
Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics (ILM), University of Leipzig, Liebigstrasse, Leipzig, Germany
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Ingo Dähnert
Ingo Dähnert
Department of Pediatric Cardiology, Faculty of Medicine, Heart Center Leipzig, University of Leipzig, Strümpellstraße, Leipzig, Germany
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Wieland Kiess
Wieland Kiess
LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Strasse, Leipzig, Germany
Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany
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Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany
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Mandy Vogel
Mandy Vogel
LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Strasse, Leipzig, Germany
Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany
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Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany
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acromegaly have reported associations between growth hormone markers and cardiac markers together with cardiovascular morbidity and mortality rates. Andreassen et al. found concordant results to ours with IGF-1 levels that were inversely associated with NT
Shota Dzemaili
Shota Dzemaili
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
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Jitske Tiemensma
Jitske Tiemensma
University of California Merced, Psychological Science, Merced, CA, USA
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Richard Quinton
Richard Quinton
Department of Endocrinology, Institute for Human Genetics, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, United Kingdom
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Nelly Pitteloud
Nelly Pitteloud
Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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Diane Morin
Diane Morin
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Faculty of Nursing Science, Laval University, Québec City, Canada
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Faculty of Nursing Science, Laval University, Québec City, Canada
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Andrew A Dwyer
Andrew A Dwyer
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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normative scores for the IPQ-R for the general population (i.e. healthy adults), comparisons were made to patients with acute or chronic pain ( 24 ), men with CHH ( 22 ) and patients with acromegaly ( 24 ) to provide a clinical context for these data. Age at
L M Mongioì
L M Mongioì
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
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R A Condorelli
R A Condorelli
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
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S La Vignera
S La Vignera
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
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A E Calogero
A E Calogero
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
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life, HRQoL): GH deficiency (Assessment of Growth Hormone Deficiency in Adults, AGHDA) ( 18 ), acromegaly (Acromegaly Quality of Life questionnaire, AcroQoL) and Cushing’s syndrome (Cushing Quality of Life questionnaire, CushingQoL) ( 19 ). Along the
Mikkel Andreassen
Mikkel Andreassen
Department of Endocrinology, Faculty of Health Science, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Faculty of Health Science, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Endocrinology, Faculty of Health Science, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Niels Jørgensen
Niels Jørgensen
Department of Growth and Reproduction, Faculty of Health Science, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Patients characteristics. Numbers Primary diagnosis Acromegaly 8 Prolactinoma 3 Mixed GH and prolactin secreting adenoma 2 Empty sella 2 Non-secreting adenoma 2
Peter Wolf
Peter Wolf
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Yvonne Winhofer
Yvonne Winhofer
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Martin Krššák
Martin Krššák
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
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High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
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Michael Krebs
Michael Krebs
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Metabolic disturbances in patients suffering from excessive production of growth hormone (GH), termed acromegaly, seem to be similar to those in the insulin resistant state, i.e. hyperglycemia, hyperinsulinemia and hypertriglyceridemia ( 63 ). Conversely
G Giuffrida
G Giuffrida
Endocrine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
PhD School of Clinical and Experimental Biomedical Sciences, University of Messina, Messina, Sicily, Italy
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PhD School of Clinical and Experimental Biomedical Sciences, University of Messina, Messina, Sicily, Italy
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F Ferraù
F Ferraù
Endocrine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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R Laudicella
R Laudicella
Nuclear Medicine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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O R Cotta
O R Cotta
Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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E Messina
E Messina
Endocrine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
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F Granata
F Granata
Department of Biomorphology, University of Messina, Messina, Sicily, Italy
Neuroradiology Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
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Neuroradiology Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
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F F Angileri
F F Angileri
Department of Biomorphology, University of Messina, Messina, Sicily, Italy
Neurosurgery Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
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Neurosurgery Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
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A Vento
A Vento
Nuclear Medicine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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A Alibrandi
A Alibrandi
Department of Economics, University of Messina, Messina, Sicily, Italy
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S Baldari
S Baldari
Nuclear Medicine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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Department of Biomorphology, University of Messina, Messina, Sicily, Italy
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S Cannavò
S Cannavò
Endocrine Unit of University Hospital ‘AOU Policlinico G. Martino’, Messina, Italy
PhD School of Clinical and Experimental Biomedical Sciences, University of Messina, Messina, Sicily, Italy
Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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PhD School of Clinical and Experimental Biomedical Sciences, University of Messina, Messina, Sicily, Italy
Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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, 17 ). Three patients affected by pituitary carcinoma were treated with 90 Y-DOTATOC (2 cycles), 90 Y-DOTATATE or 177 Lu-DOTATATE (four cycles), respectively ( 13 , 14 , 16 ). The first one was affected by Nelson syndrome, the second by acromegaly
Debra M Gordon
Debra M Gordon
University of the Witwatersrand (WITS) Donald Gordon Medical Centre, Parktown, Johannesburg, South Africa
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Pablo Beckers
Pablo Beckers
Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Emilie Castermans
Emilie Castermans
Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Sebastian J C M M Neggers
Sebastian J C M M Neggers
Department of Endocrinology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Liliya Rostomyan
Liliya Rostomyan
Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Vincent Bours
Vincent Bours
Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Patrick Petrossians
Patrick Petrossians
Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Vinciane Dideberg
Vinciane Dideberg
Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Albert Beckers
Albert Beckers
Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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Adrian F Daly
Adrian F Daly
Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium
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. SDHB c.287G>A p.Gly96Asp Pituitary P04 F 28 Pituitary macroadenoma (prolactinoma), resistant to dopamine agonists; neurosurgery (×2) None MEN1 c.1618C>T p.Pro540Ser P21 M 25 Acromegaly (macroadenoma
Karim Gariani
Karim Gariani
Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
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François R Jornayvaz
François R Jornayvaz
Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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) - Pituitary gland (TSH) - Thyroid gland (free T4) - Primary hypothyroidism (thyroid disease) - Secondary hypothyroidism (pituitary (TSH) or hypothalamic disease (TRH)) Growth hormone (GH) - Pituitary gland (GH) - Ectopic secretion - Acromegaly
Anastasia P Athanasoulia-Kaspar
Anastasia P Athanasoulia-Kaspar
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
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Matthias K Auer
Matthias K Auer
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany
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Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany
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Günter K Stalla
Günter K Stalla
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
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Mira Jakovcevski
Mira Jakovcevski
Department of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany
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, pituitary tumors such as somatotropic and corticotropic adenomas resulting in hormone excess conditions such as acromegaly ( 12 , 13 ) and Cushing’s syndrome ( 13 ) have been associated with accelerated telomere shortening ( 14 , 15 ), suggesting that TL
Veronica Kieffer
Veronica Kieffer
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Kate Davies
Kate Davies
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Christine Gibson
Christine Gibson
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Morag Middleton
Morag Middleton
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Jean Munday
Jean Munday
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Shashana Shalet
Shashana Shalet
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Lisa Shepherd
Lisa Shepherd
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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Phillip Yeoh
Phillip Yeoh
University Hospitals of Leicester NHS Trust, Great Ormond Street Hospital for Children NHS Trust, Central Manchester University Hospitals NHS Foundation Trust, NHS Grampian, Portsmouth Hospitals NHS Trust, Salford Royal Hospitals Foundation Trust, Heart of England NHS Foundation Trust, The London Clinic, Department of Diabetes and Endocrinology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
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objectives. Performance appraisal. Specialist competencies The adult endocrine nurse specialist competency framework is presented in the following tables: Competency 1 : Acromegaly. Competency 2 : Benign adrenal tumours. Competency 3 : Cushing's syndrome
