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Wenrui Wang Department of Endocrinology, The Second Hospital of Jilin University, Changchun, People’s Republic of China

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Chuan Zhang Department of Endocrinology, The Second Hospital of Jilin University, Changchun, People’s Republic of China

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-cell stress response; thus preserving β-cell mass, regaining cell maturation, improving cellular function, and delaying disease progression. Current research is focused on methods to increase β-cell numbers, maturity, function, and post

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Hathairat Rueangdetnarong Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Rattanaporn Sekararithi Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Thidarat Jaiwongkam Cardiac Electrophysiology Research and Training Center (CERT), Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Sirinart Kumfu Cardiac Electrophysiology Research and Training Center (CERT), Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Nipon Chattipakorn Cardiac Electrophysiology Research and Training Center (CERT), Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Theera Tongsong Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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Phudit Jatavan Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

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induced by hormonal change during pregnancy probably plays an important role of clinical manifestation. GDM may probably be related to oxidative stress in insulin resistance pathway, as documented in DM type 2 ( 10 ). Nevertheless, the relationship between

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Xiuzhen Hou Division 1 of Obstetrics, Cangzhou Central Hospital, Cangzhou, Hebei, China

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Junfeng Zhang Division 1 of Obstetrics, Cangzhou Central Hospital, Cangzhou, Hebei, China

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Hehong Ma Division 1 of Obstetrics, Cangzhou Central Hospital, Cangzhou, Hebei, China

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Ming Li Division 1 of Obstetrics, Cangzhou Central Hospital, Cangzhou, Hebei, China

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Pei Wang Division 1 of Obstetrics, Cangzhou Central Hospital, Cangzhou, Hebei, China

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J Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism . Cellular and Molecular Life Sciences 2016 73 3221 – 3247 . ( https://doi.org/10.1007/s00018-016-2223-0 ) 37 Chen L

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Jelena Stankovic Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Kurt Kristensen Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

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Niels Birkebæk Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

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Jens Otto Lunde Jørgensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Esben Søndergaard Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark

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found to mirror cortisol levels in response to stress, myocardial infarction, and other acute illnesses, and copeptin has been proposed as a prognostic marker in such cases ( 39 ). AVP is known to potentiate corticotropin-releasing hormone (CRH

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Ling Zhou Cangzhou Central Hospital, Cangzhou, Hebei, China

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Ruixue Zhang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Shuangyan Yang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Yaguang Zhang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Dandan Shi Cangzhou Central Hospital, Cangzhou, Hebei, China

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to attenuate the oxidative stress and to reduced complications of GDM both in the mother and the fetus ( 24 ). AS-IV, as a dual anti-oxidative and anti-inflammatory agent, could effectively inhibit both oxidative stress and inflammatory response in

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Sarah J Hall Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
Bushfire and Natural Hazards Cooperative Research Centre, East Melbourne, Victoria, Australia

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Brad Aisbett Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia

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Samuel J Robertson Institute of Sport, Exercise & Active Living (ISEAL), Victoria University, Footscray, Victoria, Australia

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Sally A Ferguson Appleton Institute, School of Health, Medical and Applied Sciences, Central Queensland University, Adelaide, South Australia, Australia

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Anne I Turner Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia

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in higher subjective stress levels than when not on-call ( 1 , 12 , 13 , 14 , 15 , 16 ). Despite this, few studies have investigated the physiological stress response to operating on-call from home ( 1 , 17 , SJ Hall, AI Turner, SA Ferguson, SJ

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Carlo Cinque Fondazione Ethoikos, Radicondoli, Italy
Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Manuela Zinni Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Anna Rita Zuena Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Chiara Giuli Fondazione Ethoikos, Radicondoli, Italy

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Sebastiano G Alemà Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Assia Catalani Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Paola Casolini Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

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Roberto Cozzolino Fondazione Ethoikos, Radicondoli, Italy

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JG Stavisky RC Greer TF Hanbury D. Cortisol response to relocation stress in Garnett’s bushbaby (Otolemur garnettii) . Contemporary Topics in Laboratory Animal Science 2005 44 22 – 24 . 3 Sheriff MJ Palme R Dantzer B Palme R Boonstra R

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Gavin P Vinson School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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Caroline H Brennan School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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actually represent a drive to lower cortisol, with its sequelae? Or is the heightened secretion of corticosteroids in drug withdrawal simply a response to stress? We here argue that the adrenal cortex has a critical role in the acquisition of addiction and

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Legh Wilkinson Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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Nicolette J D Verhoog Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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Ann Louw Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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Introduction Due to the interrelatedness of the stress and inflammatory responses, chronic persistent inflammation may be considered both a cause and a consequence of a prolonged disruption of the central HPA axis, a systemic signalling

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Selina Mäkinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland

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Yen H Nguyen Minerva Foundation Institute for Medical Research, Helsinki, Finland
University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland

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Paulina Skrobuk Minerva Foundation Institute for Medical Research, Helsinki, Finland
University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland

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Heikki A Koistinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland

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respective control, two-way ANOVA with repeated measurements, Sidak’s post hoc test. AU, arbitrary units. JNK Activation of stress kinase JNK signalling is implicated in response to ER stress ( 17 ). Palmitate increased the phosphorylation

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