Search Results

You are looking at 21 - 30 of 156 items for :

Clear All
Katrine M Lauritsen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

Search for other papers by Katrine M Lauritsen in
Google Scholar
PubMed
Close
,
Jens Hohwü Voigt Steno Diabetes Center Aarhus, Aarhus, Denmark

Search for other papers by Jens Hohwü Voigt in
Google Scholar
PubMed
Close
,
Steen Bønløkke Pedersen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Steen Bønløkke Pedersen in
Google Scholar
PubMed
Close
,
Troels K Hansen Steno Diabetes Center Aarhus, Aarhus, Denmark

Search for other papers by Troels K Hansen in
Google Scholar
PubMed
Close
,
Niels Møller Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Niels Møller in
Google Scholar
PubMed
Close
,
Niels Jessen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Biomedicine, Aarhus University, Aarhus, Denmark

Search for other papers by Niels Jessen in
Google Scholar
PubMed
Close
,
Lars C Gormsen Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Lars C Gormsen in
Google Scholar
PubMed
Close
, and
Esben Søndergaard Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

Search for other papers by Esben Søndergaard in
Google Scholar
PubMed
Close

(diabetes duration > 1 year; HbA1c 6.5–9.0% (48–75 mmol/mol) treated with metformin were randomized to empagliflozin 25 mg and placebo once-daily in a randomized, double-blinded, placebo-controlled crossover design. Patients were recruited through

Open access
Xinge Tao Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Search for other papers by Xinge Tao in
Google Scholar
PubMed
Close
,
Yanbin Xue Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Yanbin Xue in
Google Scholar
PubMed
Close
,
Rui Niu Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Search for other papers by Rui Niu in
Google Scholar
PubMed
Close
,
Wenjing Lu Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Search for other papers by Wenjing Lu in
Google Scholar
PubMed
Close
,
Huayan Yao Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Huayan Yao in
Google Scholar
PubMed
Close
,
Chunmei He Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Search for other papers by Chunmei He in
Google Scholar
PubMed
Close
,
Bin Cui Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Bin Cui in
Google Scholar
PubMed
Close
, and
Changqin Liu Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Xiamen Key Laboratory for Clinical Efficacy and Evidence-Based Research of Traditional Chinese Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Fujian Province Key Laboratory of Diabetes Translational Medicine, The First Affiliated Hospital of Xiamen University, School of medicine, Xiamen University, Xiamen, China

Search for other papers by Changqin Liu in
Google Scholar
PubMed
Close

first visit to hospitals Differences in glucose-lowering drug prescriptions between the early-onset T2DM group and the late-onset T2DM group at their first visit to hospitals are shown in Figs 1 and 2 . Metformin was the most common choice of oral

Open access
Clemens Kamrath Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany

Search for other papers by Clemens Kamrath in
Google Scholar
PubMed
Close
,
Alexander Eckert German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

Search for other papers by Alexander Eckert in
Google Scholar
PubMed
Close
,
Birgit Rami-Merhar Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria

Search for other papers by Birgit Rami-Merhar in
Google Scholar
PubMed
Close
,
Sebastian Kummer Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany

Search for other papers by Sebastian Kummer in
Google Scholar
PubMed
Close
,
Martin Wabitsch Center for Rare Endocrine Diseases, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Centre, Ulm, Germany

Search for other papers by Martin Wabitsch in
Google Scholar
PubMed
Close
,
Katharina Laubner Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany

Search for other papers by Katharina Laubner in
Google Scholar
PubMed
Close
,
Florian Kopp Forth Clinical Department of Medicine, Academic Teaching Hospital Augsburg, Augsburg, Germany

Search for other papers by Florian Kopp in
Google Scholar
PubMed
Close
,
Silvia Müther Center for Pediatric Diabetology, DRK-Kliniken-Berlin Westend, Berlin, Germany

Search for other papers by Silvia Müther in
Google Scholar
PubMed
Close
,
Steffen Mühldorfer Department for Gastroenterology, Endocrinology and Metabolic Diseases, Bayreuth University Hospital, Friedrich-Alexander University Erlangen-Nuremberg, Bayreuth, Germany

Search for other papers by Steffen Mühldorfer in
Google Scholar
PubMed
Close
, and
Reinhard W Holl German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

Search for other papers by Reinhard W Holl in
Google Scholar
PubMed
Close

) Adjusted P -values (T1D vs insulin receptoropathies) Adjusted P -values (T2D vs insulin receptoropathies) Other antidiabetic drugs 3.0 51.2 60.0 45.2 <0.001 ns <0.001 ns  Metformin 2.4 37.7 52.0 35.7 <0.001 ns

Open access
Ruixin Hu School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Ruixin Hu in
Google Scholar
PubMed
Close
,
Yanting Yuan School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Yanting Yuan in
Google Scholar
PubMed
Close
,
Chaolong Liu School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Chaolong Liu in
Google Scholar
PubMed
Close
,
Ji Zhou School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Ji Zhou in
Google Scholar
PubMed
Close
,
Lixia Ji School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Lixia Ji in
Google Scholar
PubMed
Close
, and
Guohui Jiang School of pharmacy, Qing Dao University, Qingdao, China

Search for other papers by Guohui Jiang in
Google Scholar
PubMed
Close

, Isoquinoline alkaloids, Stilbene, C7N-aminocyclic alcohols on intensifying intestinal barrier and improving islet β-cells function by regulating microbiota dysbiosis. Drugs Biguanides Recent studies have shown that metformin can modulate the

Open access
Malin Nylander Department of Obstetrics and Gynecology, Herlev Gentofte Hospital, Herlev, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Malin Nylander in
Google Scholar
PubMed
Close
,
Signe Frøssing Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark

Search for other papers by Signe Frøssing in
Google Scholar
PubMed
Close
,
Caroline Kistorp Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark

Search for other papers by Caroline Kistorp in
Google Scholar
PubMed
Close
,
Jens Faber Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark

Search for other papers by Jens Faber in
Google Scholar
PubMed
Close
, and
Sven O Skouby Department of Obstetrics and Gynecology, Herlev Gentofte Hospital, Herlev, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Sven O Skouby in
Google Scholar
PubMed
Close

risk of VTE in PCOS. Lifestyle intervention and metformin are mainstays in the treatment of PCOS, aiming at reducing body weight and insulin resistance. In women with PCOS, metformin has been found to reduce PAI-1 activity and levels of hsCRP to a

Open access
Liza Haqq School of Science and Technology, University of New England, Armidale, New South Wales 2351, Australia

Search for other papers by Liza Haqq in
Google Scholar
PubMed
Close
,
James McFarlane School of Science and Technology, University of New England, Armidale, New South Wales 2351, Australia

Search for other papers by James McFarlane in
Google Scholar
PubMed
Close
,
Gudrun Dieberg School of Science and Technology, University of New England, Armidale, New South Wales 2351, Australia

Search for other papers by Gudrun Dieberg in
Google Scholar
PubMed
Close
, and
Neil Smart School of Science and Technology, University of New England, Armidale, New South Wales 2351, Australia

Search for other papers by Neil Smart in
Google Scholar
PubMed
Close

(exercise only) Usual care Low-frequency electro-acupuncture Curi (18) 6 months 40 (12) 13 Lifestyle Metformin Guzick (19) 12 weeks 12 (6) None Lifestyle Usual care Hoeger (20) 48 weeks 38 (6) 15 Lifestyle and placebo Placebo Metformin Lifestyle and

Open access
Vittorio Unfer Health Department, UniPoliSi – Institut des Etudes Universitaires, Disentis, Switzerland

Search for other papers by Vittorio Unfer in
Google Scholar
PubMed
Close
,
Fabio Facchinetti Mother-Infant Department, University of Modena and Reggio Emilia, Modena, Italy

Search for other papers by Fabio Facchinetti in
Google Scholar
PubMed
Close
,
Beatrice Orrù Medical Affairs Department, Lo.Li. Pharma, Rome, Italy

Search for other papers by Beatrice Orrù in
Google Scholar
PubMed
Close
,
Barbara Giordani Medical Affairs Department, Lo.Li. Pharma, Rome, Italy

Search for other papers by Barbara Giordani in
Google Scholar
PubMed
Close
, and
John Nestler Departments of Medicine and Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, Virginia, USA

Search for other papers by John Nestler in
Google Scholar
PubMed
Close

improvement of IR and reduction of circulating insulin are key therapeutic targets in PCOS ( 32 ), enhancing fertility and reducing the lifelong risk for type 2 diabetes and early cardiovascular disease. Besides metformin, MI is now considered as a further

Open access
Zhaoxiang Liu Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Zhaoxiang Liu in
Google Scholar
PubMed
Close
,
Mingqiang Zhang Department of Respiratory and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Mingqiang Zhang in
Google Scholar
PubMed
Close
,
Xiaohu Shi Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

Search for other papers by Xiaohu Shi in
Google Scholar
PubMed
Close
,
Wenhui Zhao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Wenhui Zhao in
Google Scholar
PubMed
Close
,
Chenxiang Cao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Chenxiang Cao in
Google Scholar
PubMed
Close
,
Lixia Jin Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Lixia Jin in
Google Scholar
PubMed
Close
,
Yanlei Wang Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Yanlei Wang in
Google Scholar
PubMed
Close
, and
Jianzhong Xiao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Jianzhong Xiao in
Google Scholar
PubMed
Close

between the frequencies of MDSC subset cells in the peripheral blood and these metabolic indexes. Additionally, among patients who were taking metformin, a lower frequency of PD-L2 + G-MDSCs was observed compared to those who were not taking metformin

Open access
Po-Chung Cheng Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan

Search for other papers by Po-Chung Cheng in
Google Scholar
PubMed
Close
and
Chia-Hung Kao Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan

Search for other papers by Chia-Hung Kao in
Google Scholar
PubMed
Close

, two treatment groups were established according to shared decision-making between patients and their attending physicians. The control group received metformin prescription and medical nutrition consultation at disease diagnosis and during monthly

Open access
Katica Bajuk Studen Nuclear Medicine Department, University Medical Centre Ljubljana, Ljubljana, Slovenia

Search for other papers by Katica Bajuk Studen in
Google Scholar
PubMed
Close
and
Marija Pfeifer Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

Search for other papers by Marija Pfeifer in
Google Scholar
PubMed
Close

PCOS with metformin having similar effects. Translation of these short-term effects to patient-important outcomes, beyond diabetes prevention, remains uncertain ( 119 ). On the other hand, it was shown that exercise training (20 weeks) provided no

Open access