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Arpna Sharma Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Vijay Simha Baddela Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Frank Becker Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Dirk Dannenberger Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Torsten Viergutz Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Jens Vanselow Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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fluid and plasma estradiol ( 6 ). Elevated NEFA levels have detrimental effects on bovine GC ( 7 ). In human GC, saturated fatty acids (PA and SA) are known to induce apoptosis, causing potential reproductive abnormalities such as amenorrhea, which is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0011
Volume/Issue:
Volume 8: Issue 5
Open access
Ling Zhou Cangzhou Central Hospital, Cangzhou, Hebei, China

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Ruixue Zhang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Shuangyan Yang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Yaguang Zhang Cangzhou Central Hospital, Cangzhou, Hebei, China

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Dandan Shi Cangzhou Central Hospital, Cangzhou, Hebei, China

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Introduction Gestational diabetes mellitus (GDM) is a condition of glucose intolerance usually occurring during the late stage of pregnancy due to decreased maternal insulin sensitivity and increased glucose production, and often recovers

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0295
Volume/Issue:
Volume 9: Issue 9
Open access
Rui-yi Tang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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Rong Chen Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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Miao Ma Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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Shou-qing Lin Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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Yi-wen Zhang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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Ya-ping Wang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

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data given at the end of this article). Table 2 Family histories of the patients with IHH. Patient Diagnosis Family history Affected family members 1 nIHH nIHH Older brother 2 nIHH Late menarche a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0251
Volume/Issue:
Volume 6: Issue 8
Open access
Carina Hasenoehrl Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria

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Gert Schwach Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria

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Nassim Ghaffari-Tabrizi-Wizsy Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria
SFL Chicken CAM Lab, Institute of Pathophysiology and Immunology, Medical University of Graz, Graz, Austria

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Robert Fuchs Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria

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Nadine Kretschmer Department of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Graz, Austria

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Rudolf Bauer Department of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Graz, Austria

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Roswitha Pfragner Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria

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targeting major signaling pathways . Journal of Clinical Endocrinology and Metabolism 2013 98 1909 – 1917 . ( doi:10.1210/jc.2013-2583 ) 17 Guo XP Zhang XY Zhang SD . Clinical trial on the effects of shikonin mixture on later stage lung

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0105
Volume/Issue:
Volume 6: Issue 2
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Angelica Amorim Amato Department of Pharmaceutical Sciences, University of Brasilia, Brasilia, Brazil
Department of Developmental and Cell Biology, University of California, Irvine, California, USA

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Hailey Brit Wheeler Department of Developmental and Cell Biology, University of California, Irvine, California, USA

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Bruce Blumberg Department of Developmental and Cell Biology, University of California, Irvine, California, USA
Department of Pharmaceutical Sciences, University of California, Irvine, California, USA
Department of Biomedical Engineering, University of California, Irvine, California, USA

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can have profound effects later in life. For example, mothers that were in their first and second trimester of pregnancy during the Dutch Hunger Winter of 1944–1945 gave birth to children that were predisposed to obesity later in life compared with the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0578
Volume/Issue:
Volume 10: Issue 2
Open access
Keina Nishio Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Akiko Tanabe Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Risa Maruoka Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Kiyoko Nakamura Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Masaaki Takai Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Tatsuharu Sekijima Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Satoshi Tunetoh Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Yoshito Terai Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Masahide Ohmichi Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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patients. Although, the acute side effects of combination chemotherapy and CCRT are well defined, the late adverse effects have not been considered after adjuvant anticancer treatments. The long-term toxicity of surgical menopause and anticancer

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0043
Volume/Issue:
Volume 2: Issue 1
Open access
Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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be treated to prevent maternal and fetal complications, however, the management is challenged by the potential risk of severe side effects associated with the treatment ( 1 , 2 ). Furthermore, a pertinent question is on the role of thyroid

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0518
Volume/Issue:
Volume 10: Issue 2
Open access
Elizabeth Micks Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

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Greta B Raglan Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

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Jay Schulkin Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA

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, pharmacokinetics, potency, binding affinity for the PR and other steroid receptors, and effects on diverse cell types. The term ‘progestogen’ encompasses both natural and synthetic compounds that bind the PR. The need for contraceptive technology Half of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-15-0093
Volume/Issue:
Volume 4: Issue 4
Open access
Elvira C Arellanes-Licea Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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José Ávila-Mendoza Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Elizabeth C Ramírez-Martínez Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Eugenia Ramos Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Nancy Uribe-González Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Carlos Arámburo Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Teresa Morales Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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Maricela Luna Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, México

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 = 11 per group) received 7.5 mg/kg of KA (Sigma-Aldrich) i.p. (nulliparous-KA and lactating-KA) or vehicle (nulliparous-vehicle, lactating-vehicle) and were killed 24 h later by an i.p. overdose of 20% urethane (2–3 mL) ( 4 , 29 ). The pituitary gland

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0380
Volume/Issue:
Volume 7: Issue 2
Open access
Andrew R Dismukes Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Vanessa J Meyer Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Elizabeth A Shirtcliff Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA

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Katherine P Theall Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Kyle C Esteves Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Stacy S Drury Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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health outcomes as well as early life adversity ( 26 ). Elevated DHEA levels, particularly late in the day, may be particularly effective at mitigating the negative effects of heightened evening cortisol on TL, thereby providing some protection against

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0007
Volume/Issue:
Volume 5: Issue 3
Open access