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membrane lipids, which also play an important role in the aetiology of metabolic syndrome as cellular signalling molecules. The fact that the accumulation of fat in tissues, such as muscle and liver, is associated with insulin resistance throughout the
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and Laboratory Medicine 2018 56 1905 – 1912 . ( https://doi.org/10.1515/cclm-2017-1042 ) 105 Pratt MS van Faassen M Remmelts N Bischoff R & Kema IP . An antibody-free LC-MS/MS method for the quantification of intact insulin-like growth
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Department of Cardiology, Yanbian University Hospital, Yanji, China
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water–salt balance in the body ( 8 , 9 ). Also ANP is widely accepted as the diagnostic, prognostic, and cost-effective biomarkers for acute coronary syndrome (ACS) in the clinic ( 10 ). Stretch stimulation was known to be the strongest factor for ANP
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patients who were reviewed by the endocrinology service in the hospital were 16 times more likely to have a more complete laboratory workup than those not referred to endocrinology services ( 14 ). The syndrome of inappropriate anti-diuresis (SIAD) is the
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Male Klinefelter syndrome Congenital anorchia/testicular regression Kallmann syndrome Combined pituitary hormone deficiency CNS: Tumors/infiltrative diseases Chemotherapy/Radiation therapy Systemic illness e.g. (inflammatory bowel disease, celiac
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surgery and radiotherapy ( 3 ). Tertiary adrenal insufficiency (TAI) occurs as a result of suppression of HPA axis activity, as a result of exposure to supraphysiological exogenous glucocorticoids or chronic opioid use ( 4 ), leading to ACTH deficiency and
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expression of FGF21 reportedly increased in a dose-dependent manner in mice treated with exogenous TH ( 72 , 73 ). ChREBP also regulates plasma TG levels by regulating FGF21 ( 74 , 75 ). In turn, peripheral administration of FGF21 could decrease TH levels
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-vitro and in-vivo proliferative and pro-mitogenic properties of GH and insulin-like growth factor-1, which is produced following stimulation by GH, have raised concerns regarding potential associations between hGH use and the risk for tumor recurrence or
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morbidity and adult cardiovascular metabolic syndrome ( 2 , 3 , 4 ). In contrast, large for gestational age (LGA) is associated with increased risk for obstructed labor, postpartum hemorrhage, newborn hypoglycemia, obesity, and diabetes mellitus in
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Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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). Environmental factors and lifestyle can affect the balance between oxidants and antioxidants and oxidative stress accordingly ( 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 ). Exposure to exogenous sources of oxidants such as cigarette smoke, ozone, ionizing radiation