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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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common surgical complication in these patients is electrolyte disturbance characterized by hypernatremia ( 3 ). Previous studies have estimated the prevalence of hypernatremia in patients with craniopharyngioma to be between 15% and 44.8% ( 4 , 5
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blood electrolyte concentration (hypernatremia), respectively, are capable to sense changes in water balance and serum osmolality. Reduction in blood volume or increase in blood electrolyte concentration induces the release of arginine vasopressin (AVP
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that in patients with hypernatraemia, the type and volume of fluid replacement reflects the standard daily fluid and electrolyte requirement together with a component of the estimated fluid deficit such that correction of hypernatraemia is controlled
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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dataset. The decision to wean prednisolone was made by a panel of endocrinologists in a multi-disciplinary team meeting. Individuals were deemed ‘well’ if they remained asymptomatic, with an adequate blood pressure and normal electrolytes on a replacement
Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China
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Department of Neurosurgery, 900th Hospital, Fuzhou, China
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function, HPA axis function, and electrolyte levels were recorded. The criteria for HPT and HPA hypofunction were based on Bordo et al. ( 2 ). Statistical analysis All statistical analyses were performed using IBM SPSS Statistics for Windows
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, 23 , 24 , 25 , 26 , 27 ). Adrenal hormones, which cause the heartbeat to accelerate, have vasoconstrictive properties, as well as regulate water–electrolyte balance and body fluid volume, play a key role in the pathogenesis of hypertension. A
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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against 1 mL HEPES buffer, while rotating the dialysis apparatus at 20 rpm. The HEPES buffer used for equilibrium dialysis was composed to reflect the electrolyte composition and pH of serum and contained in addition to 12.570 g/L N-(2-hydroxyethyl
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indices such as serum and urinary electrolytes, arterial blood gases and electrocardiogram (ECG) results. The reference values used in this study were obtained from data collected by our laboratory regarding the healthy general population on unrestricted
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-reported renal dysfunction, congestive heart disease, depression and eating disorders were excluded. Routine measurements included prolactin, total and free testosterone, TSH, 17-hydroxyprogesterone, liver enzymes, HbA1c, plasma glucose and electrolytes
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% and it remains the commonest electrolyte disturbance seen among them ( 2 ). Hyponatremia leads to increases in morbidity, length of hospitalization and mortality among those admitted in hospital ( 3 , 4 , 5 ). A large majority of in-patients with