Search Results

You are looking at 21 - 30 of 254 items for :

Clear All
Open access

Sylvia Thiele, Anke Hannemann, Maria Winzer, Ulrike Baschant, Heike Weidner, Matthias Nauck, Rajesh V Thakker, Martin Bornhäuser, Lorenz C Hofbauer and Martina Rauner

bone mass and strength, resulting in increased osteoporotic fracture probability ( 1 ). Chronic GC therapy leads to decreased bone mineral density, and up to 50% of treated patients experience vertebral fractures ( 2 ). The complex pathogenesis of

Open access

Eva Novoa, Marcel Gärtner and Christoph Henzen

aimed to assess the possible systemic effects of IT-Dex injections on the HPA axis and bone metabolism, particularly on osteoblast function, as highly sensitive cells to exogenous glucocorticoids, in a prospective cohort study of patients receiving IT

Open access

Kaiyu Pan, Chengyue Zhang, Xiaocong Yao and Zhongxin Zhu

Introduction Calcium (Ca) is the primary nutrient of interest in bone health. It is essential to ensure adequate Ca intake to support the accelerated growth spurt during childhood and adolescence when bone accumulates and grows at a rapid rate

Open access

Farzaneh Rohani, Mohammad Reza Alai, Sedighe Moradi and Davoud Amirkashani

have a slow pattern of growth during childhood and adolescence. The patients are identified with short stature, delay bone age and puberty. Their bone age lags behind their chronological age, which is providing an indication of remaining the growth

Open access

M Ahmid, C G Perry, S F Ahmed and M G Shaikh

research over the past two decades that has demonstrated deficits in bone health and cardiac function, together with impaired quality of life in adults with CO-GHD after completion of childhood treatment ( 3 , 4 , 5 , 6 ), has questioned this practice

Open access

Enrique Soto-Pedre, Paul J Newey, John S Bevan and Graham P Leese

relationship between prolactin and all-cause cancer or breast cancer have also given inconsistent results ( 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ). Similarly, there are no consistent correlations reported between prolactin levels and bone loss or

Open access

Imane Benabbad, Myriam Rosilio, Maité Tauber, Emmanuel Paris, Anne Paulsen, Lovisa Berggren, Hiren Patel, Jean-Claude Carel and the Phoenix Study Group

were at puberty onset. It was hypothesised that the addition of leuprorelin for 2–3 years would delay progression of puberty and bone maturation, allowing prolonged efficacy of GH and increased adult or near-adult height (NAH). After commencement of the

Open access

Kaisu Luiro, Kristiina Aittomäki, Pekka Jousilahti and Juha S Tapanainen

outcome(s), bone density measurements and incidence of osteoporosis, and cardiovascular symptoms and disease. The patients were also asked to report any malignancies, operations, and neurological, psychological, respiratory, gastrointestinal, cutaneous, or

Open access

Tingting Jia, Ya-nan Wang, Dongjiao Zhang and Xin Xu

reaction ( 10 ), then lead to function changes of osteoblasts and osteoclasts ( 11 , 12 ) and impair bone formation eventually. Moreover, David et al . argued that the formation of AGEs in high glycemic conditions, may contribute to a slower rate of

Open access

Ping Li, Fei Cheng and Lei Xiu

relative to a normal population or a population with TS.). Height velocity (HV), defined as increment in height per year in centimeters, and bone age (a measure of skeletal maturity) were secondary outcome measures of this study. Data were abstracted by a