Amir Bashkin
Amir Bashkin
Department of Endocrinology, Galilee Medical Center, Nahariya, Israel
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
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Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
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Eliran Yaakobi
Eliran Yaakobi
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
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Marina Nodelman
Marina Nodelman
Department of Endocrinology, Galilee Medical Center, Nahariya, Israel
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
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Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
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Ohad Ronen
Ohad Ronen
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
Department of Otolaryngology Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel
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Department of Otolaryngology Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel
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diagnoses: overt hypothyroidism, subclinical hypothyroidism, overt thyrotoxicosis, subclinical thyrotoxicosis and non-thyroidal illness syndrome (NTIS) and/or effect of drugs. It is impossible to differentiate between the latter two based on thyroid function
Jiashu Li
Jiashu Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Aihua Liu
Aihua Liu
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Haixia Liu
Haixia Liu
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
Department of Endocrinology and Metabolism, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China
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Department of Endocrinology and Metabolism, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China
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Chenyan Li
Chenyan Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Weiwei Wang
Weiwei Wang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Cheng Han
Cheng Han
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Xinyi Wang
Xinyi Wang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Yuanyuan Zhang
Yuanyuan Zhang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Weiping Teng
Weiping Teng
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Zhongyan Shan
Zhongyan Shan
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Introduction Thyroid dysfunction is a common endocrine disorder among reproductively aged women ( 1 ), with a morbidity of 2–3%. Subclinical hypothyroidism (SCH) is the most common condition of thyroid disorders during pregnancy ( 2 ) and is
Xin He
Xin He
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Qin Yan
Qin Yan
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Chazhen Liu
Chazhen Liu
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Zhengyuan Wang
Zhengyuan Wang
Department of Nutrition Hygiene, Division of Health Risk Factor Monitoring and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Ping Liao
Ping Liao
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Tong Liu
Tong Liu
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Zehuan Shi
Zehuan Shi
Department of Nutrition Hygiene, Division of Health Risk Factor Monitoring and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Qi Song
Qi Song
Department of Nutrition Hygiene, Division of Health Risk Factor Monitoring and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Xueying Cui
Xueying Cui
Department of Nutrition Hygiene, Division of Health Risk Factor Monitoring and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Wenjing Wang
Wenjing Wang
Laboratory of Functional Medicine, Division of Chronic Non-communicable Diseases and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Jiajie Zang
Jiajie Zang
Department of Nutrition Hygiene, Division of Health Risk Factor Monitoring and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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-positive women without thyroid disease history and goiters. We defined overt hypothyroidism as TSH concentration over the 97.5th percentile with an FT4 concentration below the 2.5th percentile. Subclinical hypothyroidism was defined as TSH concentration above
Ning Yuan
Ning Yuan
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Jianbin Sun
Jianbin Sun
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Xin Zhao
Xin Zhao
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Jing Du
Jing Du
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Min Nan
Min Nan
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Qiaoling Zhang
Qiaoling Zhang
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Xiaomei Zhang
Xiaomei Zhang
Department of Endocrinology, Peking University International Hospital, Beijing, China
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Introduction Maternal subclinical hypothyroidism (SCH), which is defined as an increased thyroid-stimulating hormone (TSH) concentration beyond the upper limit of the pregnancy-specific reference range and a normal free-thyroxine (FT4
Madalena von Hafe
Madalena von Hafe
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
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João Sergio Neves
João Sergio Neves
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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Catarina Vale
Catarina Vale
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
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Marta Borges-Canha
Marta Borges-Canha
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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Adelino Leite-Moreira
Adelino Leite-Moreira
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
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with pulmonary hypertension – albeit less frequently – and atrioventricular valve regurgitation, mainly of the tricuspid valve ( 49 ). Heart failure is the main cause of increased cardiovascular mortality in both overt hyperthyroidism and subclinical
Bogumila Urgatz
Bogumila Urgatz
Merck Healthcare KGaA, Darmstadt, Germany
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Kris G Poppe
Kris G Poppe
University Hospital CHU Saint Pierre, Free University of Brussels, Brussels, Belgium
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reproduction also proposes 4.0 μIU/mL as an upper limit to the TSH reference range, unless a locally derived reference range has a higher value ( 10 ). As in other settings, the diagnosis of subclinical hypothyroidism (SCH) is made when TSH is above the upper
Xi Cao
Xi Cao
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ming Lu
Ming Lu
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Rong-Rong Xie
Rong-Rong Xie
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Li-Ni Song
Li-Ni Song
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Wei-Li Yang
Wei-Li Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Guang-Ran Yang
Guang-Ran Yang
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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% of patients with type 1 diabetes (T1DM) would suffer from DME after 10 years of follow-up ( 5 ). Thyroid dysfunctions, including clinical and subclinical thyroid dysfunction, are common diseases with a prevalence of up to 10% in the general
Clara Lundetoft Clausen
Clara Lundetoft Clausen
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Linda Maria Hilsted
Linda Maria Hilsted
Department of Clinical Biochemistry, Copenhagen University Hospital, Copenhagen, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Pal Bela Szecsi
Pal Bela Szecsi
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Lise Pedersen
Lise Pedersen
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Thomas Benfield
Thomas Benfield
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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: overt thyrotoxicosis (TSH < 0.4 mIU/L and free T 4 > 22.0 pmol/L); subclinical thyrotoxicosis (TSH < 0.4 mIU/L and 12.0 ≤ free T 4 ≤ 22.0 pmol/L); overt hypothyroidism (TSH > 4.8 mIU/L and free T 4 < 12.0 pmol/L); subclinical hypothyroidism (TSH > 4
Xiaoya Zheng
Xiaoya Zheng
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Heng Xiao
Heng Xiao
Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Jian Long
Jian Long
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Qiang Wei
Qiang Wei
Prevention of Disease Department, Chongqing Jiulongpo District Hospital of Traditional Chinese Medicine, Chongqing, China
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Liping Liu
Liping Liu
Department of Ultrasound, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Liping Zan
Liping Zan
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Wei Ren
Wei Ren
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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(ACR TI-RADS) guidelines (2017) ( 12 ). Definition of thyroid dysfunction The diagnosis of thyrotoxicosis was defined as a TSH value <0.56 µIU/mL with (overt thyrotoxicosis) or without (subclinical thyrotoxicosis) elevated FT3 or FT4 levels. The
Satoshi Higuchi
Satoshi Higuchi
Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
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Hideki Ota
Hideki Ota
Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
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Takuya Ueda
Takuya Ueda
Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
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Yuta Tezuka
Yuta Tezuka
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
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Kei Omata
Kei Omata
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
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Yoshikiyo Ono
Yoshikiyo Ono
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
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Ryo Morimoto
Ryo Morimoto
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
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Masataka Kudo
Masataka Kudo
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
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Fumitoshi Satoh
Fumitoshi Satoh
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
Division of Clinical Hypertension, Endocrinology and Metabolism, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
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Division of Clinical Hypertension, Endocrinology and Metabolism, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
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Kei Takase
Kei Takase
Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
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CPTs. We hypothesized that CMR may be able to identify the regional variance of the catecholamine-induced myocardial damage in patients with CPTs without contrast medium. We aimed to evaluate whether CMR could detect subclinical catecholamine
