Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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the solid part of the nodule. The entire procedure was performed under continuous US guidance using a high-frequency linear transducer (Philips L18-5). The output power was between 1.5 and 3.0 W and depended on the size of the solid part of the nodule
ELPEN, Inc. Research Institute, Athens, Greece
European University of Cyprus School of Medicine, Nicosia, Cyprus
Medical Genetics, Henry Dunant Hospital, Athens, Greece
National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland, USA
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of genomics for all . Cell 2019 177 5 – 7 . ( https://doi.org/10.1016/j.cell.2019.02.041 ) 5 Abul-Husn NS & Kenny EE . Personalized medicine and the power of electronic health records . Cell 2019 177 58 – 69 . ( https://doi.org/10.1016/j
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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Faculty of Biomedical Sciences, Institute of Oncology Research, Università della Svizzera Italiana, Bellinzona, Switzerland
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included in the meta-analysis ( 10 ). A sensitivity analysis was performed to examine whether overall findings were robust to the chosen analysis method. Finally, the power of meta-analysis was calculated using the metapow command. Meta-analysis was
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. Power calculation Previous short-term studies on metformin and OCP treatment in PCOS using area under the curve (AUC) for insulin during 2-h OGTT as the primary end point included a minimum of 15 patients in each group ( 20 , 21 ). There was no
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indicate an improvement in DI after vitamin D supplementation in group A, it was not statistically significant. Our study being a pilot project was not powered enough to detect a significant difference in the parameters of insulin kinetics. PCOS has been
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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autoimmune or nodular diseases. The total number of 307 patients and 206 controls satisfied the criteria of the power analysis, requiring a minimum sample size of 164 patients. Written informed consent was obtained from all the participants, who donated a
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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of the haemostatic system as outcome measures were not defined in the original study ( 7 ), which was planned in 2015, and the power of the study was determined by the effect of TRT on lean body mass. Likewise, no studies examined the effect of TRT on
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3). According to the 2010 WHO classification, high-grade G3 rectal neuroendocrine carcinomas (NECs) were defined as a tumor with Ki-67 proliferation index greater than 20% or mitotic rate greater than 20 per 10 high power fields ( 3 ). NECs are
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control’s series) and a dominant model, with a case–control ratio of 1:1.7 (597 cases and 1022 controls), we could identify an OR of 1.45 with a power of 90% and alpha = 0.05. Chi-square test was performed in a case-by-case analysis in order to evaluate
Department of Medicine (Austin Health), University of Melbourne, Heidelberg, Victoria, Australia
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Department of Medicine (Austin Health), University of Melbourne, Heidelberg, Victoria, Australia
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Department of Medicine (Austin Health), University of Melbourne, Heidelberg, Victoria, Australia
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Department of Medicine (Austin Health), University of Melbourne, Heidelberg, Victoria, Australia
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testosterone concentration were measured via immunoassays available for routine clinical care in Australia. All laboratories are accredited by the National Association of Testing Authorities. Sample size determination Power calculation was based on the