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First Pavlov State Medical University, St. Petersburg, Russia
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First Pavlov State Medical University, St. Petersburg, Russia
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performed. Analysis of the postoperative period revealed hypocalcemia, which required urgent use of calcium supplements and active form of vitamin D, in 5.6% of patients. But in most cases hypocalcemia was transient. We did not find association between serum
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developed hypocalcemia and osteomalacia. Despite hypocalcemia correction, the osteoblast number, mineral apposition rate, and bone volume were still below those of WT mice. Treating with exogenous 1,25(OH) 2 D 3 normalized the osteoblast number in mutant
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Institute of Clinical Endocrinology, Endocrinology Research Center, Moscow, Russian Federation
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parathyroid tumor. The patient underwent lower left parathyroidectomy with intraoperative lowering of the PTH to 16.2 pg/mL and postoperative hypocalcemia. Histology revealed a solitary parathyroid adenoma. The patient also had type 1 diabetes mellitus and
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combined with GHPA also complicates the treatment of the disease. Tachibana ( 13 ) reported a patient with GD and acromegaly who had primary hyperparathyroidism and underwent total parathyroidectomy and thyroidectomy, and who developed severe hypocalcemia
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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2012 397 1133 – 1137 . ( doi:10.1007/s00423-012-0981-1 ) 32 Pesce CE Shiue Z Tsai HL Umbricht CB Tufano RP Dackiw AP Kowalski J Zeiger MA. Postoperative hypocalcemia after thyroidectomy for Graves’ disease
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neonatal hypoparathyroidism . Journal of Pediatrics 2012 160 345 – 348 . ( doi:10.1016/j.jpeds.2011.09.022 ) 10.1016/j.jpeds.2011.09.022 17 Newfield RS. Recombinant PTH for initial management of neonatal hypocalcemia . New England Journal of
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-induced PAI. Immune checkpoint inhibitor-related primary hypoparathyroidism Single cases of primary hypoparathyroidism presenting with severe hypocalcemia during ICI therapy have been reported. Accordingly, two case reports involving patients with
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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Department of General Surgery, St. Elisabeth’s Hospital, Graz, Austria
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consideration of intravenous bisphosphonates which potently reduce bone resorption ( 47 ). However, a number of contraindications and potential side effects like hypocalcemia, renal impairment and atrial fibrillation need to be considered. In order to avoid
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are bisphosphonates, denosumab or selective estrogen receptor modulators (SERMs) ( 13 ). However, these compounds may have side effects. Both short-term (e.g. hypocalcemia or ocular inflammation) and long-term (e.g. osteonecrosis or atrial fibrillation
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Royal Marsden Hospital, London, UK
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New onset hypocalcemia Activating antibodies to the calcium-sensing receptor (CaSR) , of IgG1 and IgG3 subclasses with affinity to functional epitopes on the receptor, thus causing hypocalcaemia Albumin corrected calcium below 2.1 mmol/L with low