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Karim Gariani Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland

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François R Jornayvaz Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland

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(pituitary adenoma (GH) or hypothalamic mass (GHRH)) - Ectopic secretion of GHRH or GH (Bronchial carcinoid, pancreatic islet-cell tumor, small cell lung cancer, adrenal adenoma, medullary thyroid carcinoma, pheochromocytoma) - Growth hormone deficiency

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0490
Volume/Issue:
Volume 10: Issue 2
Open access
Robert Rapaport Ichan School of Medicine, New York, New York, USA

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Peter A Lee Penn State College of Medicine, Hershey, Pennsylvania, USA

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Judith L Ross Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Nemours/DuPont Hospital for Children, Wilmington, Delaware, USA

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Paul Saenger Winthrop University Hospital, Mineola, New York, USA

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Vlady Ostrow Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Giuseppe Piccoli Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Introduction Treatment with recombinant human growth hormone (GH) is widely utilized for improving height in children with growth failure and conditions in which it is efficacious, including isolated growth hormone deficiency (IGHD

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0286
Volume/Issue:
Volume 7: Issue 10
Open access
Jose M Garcia GRECC VA Puget Sound HCS/University of Washington, Seattle, Washington, USA

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Beverly M K Biller Massachusetts General Hospital, Neuroendocrine Unit, Boston, Massachusetts, USA

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Márta Korbonits Barts and the London School of Medicine, Queen Mary University of London, Endocrinology, London, UK

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Vera Popovic University of Belgrade, Medical Faculty, Belgrade, Serbia

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Anton Luger Division of Endocrinology and Metabolism, Medical University, General Hospital, Vienna, Austria

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Christian J Strasburger Charité-Universitätsmedizin, Clinical Endocrinology CCM, Berlin, Germany

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Philippe Chanson Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, and Université Paris-Saclay, Univ. Paris-Sud, Inserm, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Le Kremlin-Bicêtre, France

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Ronald Swerdloff The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA

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Christina Wang The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA

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Rosa Rosanna Fleming Strongbridge Biopharma, Trevose, Pennsylvania, USA

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Fredric Cohen Strongbridge Biopharma, Trevose, Pennsylvania, USA

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Nicola Ammer Aeterna Zentaris GmbH, Frankfurt, Hessen, Germany

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Gilbert Mueller Aeterna Zentaris GmbH, Frankfurt, Hessen, Germany

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Nicky Kelepouris Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Frank Strobl Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Vlady Ostrow Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Kevin C J Yuen University of Arizona College of Medicine and Creighton School of Medicine, Barrow Pituitary Center, Barrow Neurological Institute, Phoenix, Arizona, USA

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Introduction Adult growth hormone deficiency (AGHD) is a clinical syndrome characterized by abnormal body composition, unfavorable cardiovascular risk, cardiac dysfunction, decreased bone mineral density, and glucose intolerance ( 1 , 2

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0491
Volume/Issue:
Volume 10: Issue 1
Open access
Nidan Qiao Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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pituitary neoplasms, acromegaly, Cushing’s disease, craniopharyngioma and growth hormone deficiency. More than half of the studies were published in the recent 2 years. Table 2 Summary of studies on sellar region disease using machine learning methods

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0156
Volume/Issue:
Volume 8: Issue 7
Open access
Jelena Stankovic Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Kurt Kristensen Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

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Niels Birkebæk Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

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Jens Otto Lunde Jørgensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Esben Søndergaard Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark

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BMK Radovick S Carmichael JD Jasim S Pantalone KM & Hoffman AR . American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of growth hormone deficiency in adults and patients

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-23-0042
Volume/Issue:
Volume 12: Issue 11
Open access
Mark R Postma Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Pia Burman Department of Endocrinology, Skane University Hospital Malmö, University of Lund, Lund, Sweden

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André P van Beek Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Introduction Adult growth hormone deficiency (AGHD) is characterized by changes in body fat distribution with increased central adiposity, hyperlipidaemia, increased predisposition to atherogenesis and reduced bone remodelling activity. It is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0098
Volume/Issue:
Volume 9: Issue 7
Open access
Martin Bidlingmaier Medizinische Klinik und Poliklinik IV, LMU Klinikum, Ludwig-Maximilians University, Munich, Germany

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Helena Gleeson Department of Endocrinology, Queen Elizabeth Hospital, Birmingham, UK

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Ana-Claudia Latronico Department of Internal Medicine, Discipline of Endocrinology and Metabolism, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil

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Martin O Savage Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK

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, guide genetic counselling (including screening of family members) and allow prompt intervention in children with pubertal disorders. Integration of precision medicine into transitional care of patients with growth hormone deficiency

Article Type:
Review Article
Collections:
Paediatric Endocrinology
DOI:
https://doi.org/10.1530/EC-22-0177
Volume/Issue:
Volume 11: Issue 10
Open access
H A Booij Department of Neurology, Medisch Spectrum Twente, Enschede, the Netherlands

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W D C Gaykema Roessingh Rehabilitation Center, Enschede, the Netherlands

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K A J Kuijpers Roessingh Rehabilitation Center, Enschede, the Netherlands

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M J M Pouwels Department of Endocrinology, Medisch Spectrum Twente, Enschede, the Netherlands

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H M den Hertog Department of Neurology, Medisch Spectrum Twente, Enschede, the Netherlands

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injury due to stroke as well. PD and stroke Literature on the prevalence of PD in stroke is scarce, especially for the subacute and chronic phase. The most commonly found endocrine disturbance is growth hormone deficiency (GHD) ( Table 1 ). This

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0147
Volume/Issue:
Volume 7: Issue 6
Open access
Charlotte Höybye Department of Endocrinology and Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden

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Beverly M K Biller Neuroendocrine Unit, Massachusetts General Hospital, Massachusetts General Hospital, Boston, Massachusetts, USA

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Jean-Marc Ferran Qualiance ApS, Copenhagen, Denmark

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Murray B Gordon Allegheny Neuroendocrinology Center, Division of Endocrinology, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA

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Nicky Kelepouris US Medical Affairs-Rare Endocrine Disorders, Novo Nordisk, Inc, Plainsboro, New Jersey, USA

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Navid Nedjatian Global Medical Affairs – Rare Endocrine Disorders, Novo Nordisk Health Care AG, Zurich, Switzerland

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Anne H Olsen Epidemiology, Novo Nordisk A/S, Soborg, Denmark

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Matthias M Weber Unit of Endocrinology, 1, Medical Department, University Hospital, Universitätsmedizin Mainz, der Johannes Gutenberg-Universität, Mainz, Germany

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Introduction Adult growth hormone deficiency (AGHD) is associated with increased visceral adiposity, insulin resistance, dyslipidaemia and hyperglycaemia ( 1 ). AGHD may persist from childhood or be acquired in adulthood as a result of

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-22-0267
Volume/Issue:
Volume 12: Issue 1
Open access
Anna-Pauliina Iivonen Institute of Biomedicine/Physiology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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Johanna Känsäkoski Institute of Biomedicine/Physiology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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Atte Karppinen Department of Neurosurgery, Helsinki University Hospital, Helsinki, Finland

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Leena Kivipelto Department of Neurosurgery, Helsinki University Hospital, Helsinki, Finland

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Camilla Schalin-Jäntti Department of Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Auli Karhu Department of Medical and Clinical Genetics, RPU, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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Taneli Raivio Institute of Biomedicine/Physiology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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), underlie maternally inherited gingival fibromatosis and autosomal dominant growth hormone deficiency which, in some patients, expanded to multiple pituitary hormone deficiency ( 9 ). Intriguingly, KCNQ1 was shown to be expressed in mouse hypothalamic GHRH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0123
Volume/Issue:
Volume 7: Issue 5
Open access