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Selina Mäkinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Neeta Datta Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Yen H Nguyen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Petro Kyrylenko Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Markku Laakso Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland

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Heikki A Koistinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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-mediated. As glucose uptake was increased and glucose oxidation markedly diminished, glucose fluxes were directed towards non-oxidative glucose disposal in muscle cells treated with lactone-form simvastatin. The increase in glucose incorporation into glycogen

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0444
Volume/Issue:
Volume 9: Issue 11
Open access
J Chycki Department of Sports Training, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland

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A Zajac Department of Sports Training, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland

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M Michalczyk Department of Sports Nutrition, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland

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A Maszczyk Department of Methodology and Statistics, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland

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J Langfort Department of Sports Nutrition, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland

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operates in a different manner in this group of subjects, and may be attributed to their dietary status, which was characterized by a significantly higher energy intake from fats ( Table 1 ). The driving force of the FFA flux from vascular space to muscle

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0216
Volume/Issue:
Volume 8: Issue 7
Open access
Lili Liu Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China

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Zhuo Shao Department of General Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, Shanghai, China

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Ying Xia Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China

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Jiabi Qin Department of Epidemiology & Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China

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Yang Xiao Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China

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Zhiguang Zhou Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China

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Zubing Mei Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China

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Honkanen-Scott M Shaw JAM Lovat PE Arden C. Glucagon-like peptide 1 protects pancreatic beta-cells from death by increasing autophagic flux and restoring lysosomal function . Diabetes 2017 66 1272 – 1285 . ( https://doi.org/10.2337/db16-1009 ) 10

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0546
Volume/Issue:
Volume 8: Issue 3
Open access
Melody Lok-Yi Chan Department of Medicine, University of Hong Kong, Hong Kong SAR

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Sammy Wing-Ming Shiu Department of Medicine, University of Hong Kong, Hong Kong SAR

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Ching-Lung Cheung Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong SAR

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Anskar Yu-Hung Leung Department of Medicine, University of Hong Kong, Hong Kong SAR

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Kathryn Choon-Beng Tan Department of Medicine, University of Hong Kong, Hong Kong SAR

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synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol flux . Arteriosclerosis, Thrombosis, and Vascular Biology 2004 24 2365 – 2371 . ( https://doi.org/10.1161/01.ATV.0000148707.93054.7d ) 24

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-22-0019
Volume/Issue:
Volume 11: Issue 6
Open access
Muhammad Fahad Arshad Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK

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Ahmed Iqbal Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK

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James Weeks Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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Ines Fonseca Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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Alia Munir Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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William Bennet Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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the risk of adverse neurological events from rapid bidirectional fluxes in serum sodium. At variance with ESE guidelines, our data indicate that an additional strategy that may prevent or slow down overcorrection, and reduce the need for re

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0007
Volume/Issue:
Volume 11: Issue 5
Open access
Karim Gariani Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland

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François R Jornayvaz Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland

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lipogenesis and adipose tissue lipolysis, leading to an increased flux of fatty acids to the liver ( 30 ). Insulin resistance will also lead to adipose tissue dysfunction inducing secretion of inflammatory cytokines ( 31 ). Intrahepatic accumulation of fatty

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0490
Volume/Issue:
Volume 10: Issue 2
Open access
Huma Qamar Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada

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Nandita Perumal Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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Eszter Papp Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada

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Alison D Gernand Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania, USA

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Abdullah Al Mahmud Nutrition and Clinical Services Division, International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh

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Daniel E Roth Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada

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the placenta ( 14 , 15 ). As such, maternal PTH likely regulates bone growth through transplacental calcium flux or other indirect mechanisms. During pregnancy, the increased demand for calcium to support fetal growth is met by increasing maternal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0056
Volume/Issue:
Volume 10: Issue 3
Open access
Elisabet Einarsdottir Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Molecular Neurology Research Program, University of Helsinki, Helsinki, Finland
Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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Minna Pekkinen Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Kaarel Krjutškov Molecular Neurology Research Program, University of Helsinki, Helsinki, Finland
Competence Centre on Health Technologies, Tartu, Estonia

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Shintaro Katayama Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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Juha Kere Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Molecular Neurology Research Program, University of Helsinki, Helsinki, Finland
Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
School of Basic and Medical Biosciences, King’s College London, Guy’s Hospital, London, United Kingdom

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Outi Mäkitie Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Department of Molecular Medicine and Surgery and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden

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Heli Viljakainen Folkhälsan Institute of Genetics, University of Helsinki, Helsinki, Finland
Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland

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mediated by calcium fluxes remains unsolved ( 31 ). The current study can be regarded as a pilot study or descriptive study on the transcriptomic effects of vitamin D supplementation due to lack of functional outcomes. Future work should ideally be

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0537
Volume/Issue:
Volume 8: Issue 5
Open access
Arpna Sharma Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Vijay Simha Baddela Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Frank Becker Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Dirk Dannenberger Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Torsten Viergutz Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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Jens Vanselow Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

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some other proteins like MLN4 have been known to possess STAR- like activity in promoting cholesterol flux into mitochondria ( 55 ). From our data, it became very clear that the saturated fatty acids tested (PA, SA) elicited very different, partly

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0011
Volume/Issue:
Volume 8: Issue 5
Open access
Chanyang Kim Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Korea

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Seungjoon Park Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea

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main regulators in neuroprotection in PD. As one of the gatekeepers of the Krebs cycle, CS plays an important role in regulating the energy flux and metabolic rate of the cell. Impaired activity of CS is known to interfere mitochondrial function and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0350
Volume/Issue:
Volume 7: Issue 3
Open access