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stress-related cortisol rise by the interference of antibodies directed against those viral antigens with the host’s natural secretion of corticosteroids ( 8 ). Recent studies in patients with SARS-CoV-2 infections confirmed significantly impaired
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cortisol due to rapid conversion by CYP3A4 in the liver, perhaps during a first pass after adsorption from the gut. A second factor may be an increase in corticosteroid binding globulin during mitotane treatment (23) . Induction of CYP3A4 by mitotane needs
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presence of both GR and MR in dexamethasone-exposed human hippocampal tissue We next visualized the subcellular distribution of the corticosteroid receptors in the human hippocampus. As expected, IF staining of GR in the dexamethasone-treated tissue
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corticosteroid treatment could impact NLR values and MR findings, we performed a separate analysis excluding those who were receiving or have received corticosteroid treatments over 3 months before enrollment. A Cox proportional hazards model was used to identify
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with adjunctive therapy as cholestyramine or corticosteroids was not used. Figure 1 Accumulative doses of iodine solution in 27 patients with uncontrolled Graves’ disease. Background information and side effects necessitating treatment
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Metabolism 2014 99 111 – 118 . ( https://doi.org/10.1210/JC.2013-2449 ) 13 Vulto A Bergthorsdottir R Faassen van M Kema IP Johannsson G van Beek AP . Residual endogenous corticosteroid production in patients with adrenal insufficiency
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Endocrinology 2007 16 37 – 44 . ( https://doi.org/10.1297/cpe.16.37 ) 45 Bonanno C Wapner RJ . Antenatal corticosteroids in the management of preterm birth: are we back where we started? Obstetrics and Gynecology Clinics of North America 2012 39 47 – 63
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pituitary insufficiency. Thirty-four out of the 39 patients with anterior pituitary insufficiency had an insufficiency of corticotroph axis and were therefore receiving a corticosteroid therapy. Four patients with central DI (three with partial DI) received
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). Exclusion criteria were systemic corticosteroid treatment; pregnancy; severe comorbidities or cognitive deficiency (cancer, hepatic failure, end-stage renal disease (ESRD), diagnosed Cushing’s syndrome/disease, stroke with cognitive deficiency, psychotic