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Zhiwei Zhang Department of Obstetrics and Gynecology, Liaocheng People’s Hospital, Liaocheng, Shandong, China

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Hui Zhao Department of Obstetrics and Gynecology, Liaocheng People’s Hospital, Liaocheng, Shandong, China

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Aixia Wang Department of Obstetrics and Gynecology, Liaocheng People’s Hospital, Liaocheng, Shandong, China

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. ( https://doi.org/10.3892/or.2016.4978 ) 34 Oi-Kano Y Iwasaki Y Nakamura T Watanabe T Goto T Kawada T Watanabe K Iwai K Oleuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0466
Volume/Issue:
Volume 10: Issue 1
Open access
Jeyanthini Risikesan Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Birgitte Nellemann Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

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Britt Christensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Jens Otto Lunde Jørgensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Søren Nielsen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark

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glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice . PLoS ONE 2017 12 e0173661. ( https://doi.org/10.1371/journal.pone.0173661 ) 11 Christensen B Nellemann B

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0305
Volume/Issue:
Volume 9: Issue 12
Open access
Helle Keinicke Insulin and Device Trial Operations, Novo Nordisk A/S, Søborg, Denmark

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Gao Sun Pharmacology and Histopathology, Novo Nordisk A/S, China

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Caroline M Junker Mentzel Department of Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Merete Fredholm Department of Veterinary Clinical and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Linu Mary John Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Birgitte Andersen Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Kirsten Raun Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Marina Kjaergaard Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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production may supply the brown adipose tissue (BAT) with fuel, secondary to increases in EE expenditure ( 48 , 49 ). Villarroya and colleagues have previously demonstrated that FGF21 stimulate the glucose uptake in BAT and specifically induce the glucose

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0152
Volume/Issue:
Volume 9: Issue 8
Open access
L Bahler Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands

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H J Verberne Nuclear Medicine, Academic Medical Center, Amsterdam, The Netherlands

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E Brakema Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands

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R Tepaske Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands

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J Booij Nuclear Medicine, Academic Medical Center, Amsterdam, The Netherlands

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J B Hoekstra Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands

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F Holleman Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands

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subjects . Diabetes Care 1996 19 667 – 670 . ( doi:10.2337/diacare.19.6.667 ) 11 Bahler L Verberne HJ Soeters MR Booij J Hoekstra JB Holleman F. Dopaminergic Effects on Brown Adipose Tissue (DEBAT): a prospective

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Research Article
DOI:
https://doi.org/10.1530/EC-16-0051
Volume/Issue:
Volume 5: Issue 6
Open access
John E M Midgley
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Rolf Larisch North Lakes Clinical, Department of Nuclear Medicine, Medical Department I, Ruhr Center for Rare Diseases (CeSER), 20 Wheatley Avenue, Ilkley LS29 8PT, UK

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Johannes W Dietrich North Lakes Clinical, Department of Nuclear Medicine, Medical Department I, Ruhr Center for Rare Diseases (CeSER), 20 Wheatley Avenue, Ilkley LS29 8PT, UK
North Lakes Clinical, Department of Nuclear Medicine, Medical Department I, Ruhr Center for Rare Diseases (CeSER), 20 Wheatley Avenue, Ilkley LS29 8PT, UK

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Rudolf Hoermann North Lakes Clinical, Department of Nuclear Medicine, Medical Department I, Ruhr Center for Rare Diseases (CeSER), 20 Wheatley Avenue, Ilkley LS29 8PT, UK

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that rT 3 , when infused into rats, inhibited deiodinase type 2 activity in the pituitary, cerebral cortex and brown adipose tissue, but interestingly, this did not have much impact on circulating T 4 , T 3 and TSH concentrations in the animals

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0056
Volume/Issue:
Volume 4: Issue 4
Open access
Anna C Simcocks Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia

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Kayte A Jenkin Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia
School of Science and Health, Western Sydney University, Campbelltown, New South Wales, Australia

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Lannie O’Keefe Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia

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Chrishan S Samuel Cardiovascular Disease Program, Biomedicine Discovery Institute and Department of Pharmacology, Monash University, Clayton, Victoria, Australia

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Michael L Mathai Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia
The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, Victoria, Australia

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Andrew J McAinch Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia
Australian Institute for Musculoskeletal Science (AIMSS), College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia

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Deanne H Hryciw Institute for Health and Sport, Victoria University, St Albans campus, Melbourne, Victoria, Australia
School of Environment and Sciences, Griffith University, Nathan, Queensland, Australia

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percentage, while brown adipose tissue (BAT) depots were not altered by treatment with this compound. There was also an increase in kidney and liver mass in the DIO + O-1602-treated group while heart mass was unaffected by the chronic treatment ( Table 4

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0535
Volume/Issue:
Volume 8: Issue 3
Open access
Agnieszka Bogusz Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany
Department of Endocrinology and Diabetology, The Children’s Memorial Health Institute, Warsaw, Poland

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Svenja Boekhoff Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany

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Monika Warmuth-Metz Department of Neuroradiology, University Hospital, Würzburg, Germany

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Gabriele Calaminus Department of Pediatric Oncology and Hematology, University Hospital, Bonn, Germany

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Maria Eveslage Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

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Hermann L Müller Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany

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regulators for thermoregulation and locomotion mediating leptin-induced sympathetic activation of brown adipose tissue and energy expenditure ( 47 ). Studies in a rodent model for lesion-induced hypothalamic obesity showed that mainly lesions affecting these

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0074
Volume/Issue:
Volume 8: Issue 5
Open access
Antonia Ertelt Equine Clinic, Free University of Berlin, Berlin, Germany

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Ann-Kristin Barton Equine Clinic, Free University of Berlin, Berlin, Germany

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Robert R Schmitz Equine Clinic, Free University of Berlin, Berlin, Germany

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Heidrun Gehlen Equine Clinic, Free University of Berlin, Berlin, Germany

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, consists mainly of adipocytes. White and brown adipose tissues in both horses and humans must be differentiated: the former tissue contains single lipid droplets and the latter contains numerous smaller droplets. In addition to serving as fat storage

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-14-0038
Volume/Issue:
Volume 3: Issue 3
Open access
Devis Pascut Fondazione Italiana Fegato – ONLUS, Trieste, Italy

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Sofia Tamini Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy

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Silvia Bresolin Laboratory of Onco-Hematology, Department of Women’s and Children’s Health, University of Padova, Padova, Italy

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Pablo Giraudi Fondazione Italiana Fegato – ONLUS, Trieste, Italy

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Giuseppe Basso Laboratory of Onco-Hematology, Department of Women’s and Children’s Health, University of Padova, Padova, Italy

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Alessandro Minocci Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy

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Claudio Tiribelli Fondazione Italiana Fegato – ONLUS, Trieste, Italy

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Graziano Grugni Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy

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Alessandro Sartorio Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy

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with obesity had already been proven ( 28 ). In particular, mir-92a-3p negatively correlated with the brown adipose tissue activity ( 29 ), while, the liver-enriched miR-122 was reported to work as central regulator of cholesterol and lipid metabolism

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0329
Volume/Issue:
Volume 7: Issue 12
Open access
Pernille Bækgaard Udesen The Fertility Clinic, Department of Gynecology and Obstetrics, Zealand University Hospital, Køge, Denmark
Department of Science and Environment, Roskilde University, Roskilde, Denmark

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Dorte Glintborg Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Anja Elaine Sørensen Department of Science and Environment, Roskilde University, Roskilde, Denmark

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Rikke Svendsen Department of Science and Environment, Roskilde University, Roskilde, Denmark

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Nanna Louise Skov Nielsen Department of Science and Environment, Roskilde University, Roskilde, Denmark
Department of Clinical Immunology, Næstved Hospital, Næstved, Denmark

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Marie Louise Muff Wissing Aleris Hamlet Hospital Group, The Fertility Clinic, Søborg, Denmark

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Marianne Skovsager Andersen Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Anne Lis Mikkelsen Englund The Fertility Clinic, Department of Gynecology and Obstetrics, Zealand University Hospital, Køge, Denmark

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Louise Torp Dalgaard Department of Science and Environment, Roskilde University, Roskilde, Denmark

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-sensitive tissues of obese patients ( 10 , 11 ) and in patients with T2D ( 12 , 13 , 14 ). The role of miRNAs in metabolism and diabetes is quite complex ( 15 ) and involves many different tissues for example, liver, beta-cells, white and brown adipose tissue, as

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0195
Volume/Issue:
Volume 9: Issue 11
Open access