Search Results

You are looking at 21 - 30 of 81 items for :

  • "acromegaly" x
Clear All
Marko Stojanovic Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Marko Stojanovic in
Google Scholar
PubMed
Close
,
Zida Wu Department of Medicine for Endocrinology, Diabetes and Nutritional Medicine, Charité Universitätsmedizin, Campus Mitte, Berlin, Germany

Search for other papers by Zida Wu in
Google Scholar
PubMed
Close
,
Craig E Stiles Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

Search for other papers by Craig E Stiles in
Google Scholar
PubMed
Close
,
Dragana Miljic Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Dragana Miljic in
Google Scholar
PubMed
Close
,
Ivan Soldatovic University of Belgrade, Medical Faculty, Belgrade, Serbia
Insitute of Medical Statistics and Informatics, Belgrade, Serbia

Search for other papers by Ivan Soldatovic in
Google Scholar
PubMed
Close
,
Sandra Pekic Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Sandra Pekic in
Google Scholar
PubMed
Close
,
Mirjana Doknic Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Mirjana Doknic in
Google Scholar
PubMed
Close
,
Milan Petakov Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Milan Petakov in
Google Scholar
PubMed
Close
,
Vera Popovic University of Belgrade, Medical Faculty, Belgrade, Serbia

Search for other papers by Vera Popovic in
Google Scholar
PubMed
Close
,
Christian Strasburger Department of Medicine for Endocrinology, Diabetes and Nutritional Medicine, Charité Universitätsmedizin, Campus Mitte, Berlin, Germany

Search for other papers by Christian Strasburger in
Google Scholar
PubMed
Close
, and
Márta Korbonits Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

Search for other papers by Márta Korbonits in
Google Scholar
PubMed
Close

-secreting macroadenomas, resistant to somatostatin analogue (SA) treatment ( 17 , 18 ). AIP is thought to play an important role in the response to SA in acromegaly ( 19 ). Neither the exact mechanism of AIP influence on proliferation inhibition, nor its possible role in

Open access
Adrian F Daly Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

Search for other papers by Adrian F Daly in
Google Scholar
PubMed
Close
,
David A Cano Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

Search for other papers by David A Cano in
Google Scholar
PubMed
Close
,
Eva Venegas-Moreno Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

Search for other papers by Eva Venegas-Moreno in
Google Scholar
PubMed
Close
,
Patrick Petrossians Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

Search for other papers by Patrick Petrossians in
Google Scholar
PubMed
Close
,
Elena Dios Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

Search for other papers by Elena Dios in
Google Scholar
PubMed
Close
,
Emilie Castermans Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

Search for other papers by Emilie Castermans in
Google Scholar
PubMed
Close
,
Alvaro Flores-Martínez Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

Search for other papers by Alvaro Flores-Martínez in
Google Scholar
PubMed
Close
,
Vincent Bours Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

Search for other papers by Vincent Bours in
Google Scholar
PubMed
Close
,
Albert Beckers Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

Search for other papers by Albert Beckers in
Google Scholar
PubMed
Close
, and
Alfonso Soto-Moreno Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

Search for other papers by Alfonso Soto-Moreno in
Google Scholar
PubMed
Close

thyrotropinomas are rarer ( 1 , 2 , 3 ). Treatment of pituitary adenomas varies according to the pituitary adenoma sub-type. Responses to therapy are variable due to heterogeneity among patient profiles and tumor characteristics. For instance, acromegaly

Open access
Julie M Silverstein Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8127, St Louis, Missouri 63110, USA

Search for other papers by Julie M Silverstein in
Google Scholar
PubMed
Close

Introduction Acromegaly is a rare hormonal condition that develops most commonly from benign somatotroph pituitary adenomas and has a prevalence of 36–69 cases per million and an incidence of 3–4 cases per million per year (1, 2, 3, 4) . However

Open access
Marta Araujo-Castro Neuroendocrinology Unit, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Instituto de Investigación Biomédica Ramón y Cajal, Madrid, Spain

Search for other papers by Marta Araujo-Castro in
Google Scholar
PubMed
Close
,
Héctor Pian Endocrinology Unit, Department of Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain

Search for other papers by Héctor Pian in
Google Scholar
PubMed
Close
,
Ignacio Ruz-Caracuel Endocrinology Unit, Department of Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain

Search for other papers by Ignacio Ruz-Caracuel in
Google Scholar
PubMed
Close
,
Alberto Acitores Cancela Neuroendocrinology Unit, Department of Neurosurgery, Hospital Universitario Ramón y Cajal, Madrid, Spain

Search for other papers by Alberto Acitores Cancela in
Google Scholar
PubMed
Close
,
Eider Pascual-Corrales Neuroendocrinology Unit, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Instituto de Investigación Biomédica Ramón y Cajal, Madrid, Spain

Search for other papers by Eider Pascual-Corrales in
Google Scholar
PubMed
Close
, and
Víctor Rodríguez Berrocal Neuroendocrinology Unit, Department of Neurosurgery, Hospital Universitario Ramón y Cajal, Madrid, Spain
Endoscopic Skull Base Unit, Department of Neurosurgery, Hospital Universitario HM Puerta del Sur, Madrid, Spain

Search for other papers by Víctor Rodríguez Berrocal in
Google Scholar
PubMed
Close

Introduction Acromegaly is a rare disease characterized by the overproduction of growth hormone (GH), which is commonly secreted by a pituitary adenoma (PA). Because of cardiovascular, respiratory, and metabolic comorbidities, patients with

Open access
Nadia Sabbah Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
Hôpital de Cayenne, Service d’Endocrinologie et des Maladies Métaboliques, Cayenne, Guyane Française

Search for other papers by Nadia Sabbah in
Google Scholar
PubMed
Close
,
Peter Wolf Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

Search for other papers by Peter Wolf in
Google Scholar
PubMed
Close
,
Céline Piedvache Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Unité de Recherche Clinique, Le Kremlin-Bicêtre, France

Search for other papers by Céline Piedvache in
Google Scholar
PubMed
Close
,
Séverine Trabado Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service de Génétique Moléculaire, Pharmacogénétique et Hormonologie, Le Kremlin-Bicêtre, France

Search for other papers by Séverine Trabado in
Google Scholar
PubMed
Close
,
Tristan Verdelet Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France

Search for other papers by Tristan Verdelet in
Google Scholar
PubMed
Close
,
Catherine Cornu Centre d’Investigation Clinique, INSERM CIC1407/UMR5558, Hospices Civils de Lyon, Bron, France

Search for other papers by Catherine Cornu in
Google Scholar
PubMed
Close
,
Jean-Claude Souberbielle Assistance Publique-Hôpitaux de Paris, Hôpital Necker, Service d’Explorations Fonctionnelles, Paris, France

Search for other papers by Jean-Claude Souberbielle in
Google Scholar
PubMed
Close
, and
Philippe Chanson Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France

Search for other papers by Philippe Chanson in
Google Scholar
PubMed
Close

Introduction IGF-1 measurement is important for the diagnosis and management of patients with growth hormone (GH) deficiency or acromegaly as well as in their follow-up ( 1 , 2 ). We previously established normative data for six IGF-I assays

Open access
Paula Bruna Araujo Department of Internal Medicine and Endocrine Unit, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
Diagnósticos da América SA, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Paula Bruna Araujo in
Google Scholar
PubMed
Close
,
Leandro Kasuki Department of Internal Medicine and Endocrine Unit, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
Neuroendocrinology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Unit, Hospital Federal de Bonsucesso, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Leandro Kasuki in
Google Scholar
PubMed
Close
,
Carlos Henrique de Azeredo Lima Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Carlos Henrique de Azeredo Lima in
Google Scholar
PubMed
Close
,
Liana Ogino Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Liana Ogino in
Google Scholar
PubMed
Close
,
Aline H S Camacho Neuropathology Laboratory Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
National Cancer Institute, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Aline H S Camacho in
Google Scholar
PubMed
Close
,
Leila Chimelli Neuropathology Laboratory Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Leila Chimelli in
Google Scholar
PubMed
Close
,
Márta Korbonits Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, Charterhouse Square, London, UK

Search for other papers by Márta Korbonits in
Google Scholar
PubMed
Close
, and
Monica R Gadelha Department of Internal Medicine and Endocrine Unit, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
Neuroendocrinology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Monica R Gadelha in
Google Scholar
PubMed
Close

hydrocarbon receptor-interacting protein ( AIP ) gene mutations ( AIPmut ) were first described by Vierimaa and coworkers in 2006 ( 3 ). This study has found AIPmut in seemingly sporadic acromegaly patients and in familial isolated pituitary adenomas (FIPA

Open access
Nidan Qiao Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Nidan Qiao in
Google Scholar
PubMed
Close

pituitary neoplasms, acromegaly, Cushing’s disease, craniopharyngioma and growth hormone deficiency. More than half of the studies were published in the recent 2 years. Table 2 Summary of studies on sellar region disease using machine learning methods

Open access
Amir H Zamanipoor Najafabadi Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands
Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands
Department of Neurosurgery, University Neurosurgical Centre Holland (UNCH), Leiden University Medical Centre, Haaglanden Medical Centre and Haga Teaching Hospitals, Leiden and The Hague, The Netherlands

Search for other papers by Amir H Zamanipoor Najafabadi in
Google Scholar
PubMed
Close
,
Merel van der Meulen Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

Search for other papers by Merel van der Meulen in
Google Scholar
PubMed
Close
,
Ana Luisa Priego Zurita Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

Search for other papers by Ana Luisa Priego Zurita in
Google Scholar
PubMed
Close
,
S Faisal Ahmed Chair of Work Package of E-Health & ICT of Endo-ERN, Developmental Endocrinology Research Group, School of Medicine, Dentistry & Nursing, University of Glasgow and Office for Rare Conditions, Royal Hospital for Children & Queen Elizabeth University Hospital, Glasgow, UK

Search for other papers by S Faisal Ahmed in
Google Scholar
PubMed
Close
,
Wouter R van Furth Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands

Search for other papers by Wouter R van Furth in
Google Scholar
PubMed
Close
,
Evangelia Charmandari Pediatric Chair Main Thematic Group 6 Pituitary of Endo-ERN, Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, ‘Aghia Sophia’ Children’s Hospital, Athens, Greece

Search for other papers by Evangelia Charmandari in
Google Scholar
PubMed
Close
,
Olaf Hiort Pediatric Chair and Deputy Coordinator of Endo-ERN, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Lübeck, Lübeck, Germany

Search for other papers by Olaf Hiort in
Google Scholar
PubMed
Close
,
Alberto M Pereira Adult Chair and Coordinator of Endo-ERN, Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Amsterdam, The Netherlands

Search for other papers by Alberto M Pereira in
Google Scholar
PubMed
Close
,
Mehul Dattani London Centre for Pediatric Endocrinology and Diabetes at Great Ormond Street Children's Hospital and University College London Hospitals, London, UK

Search for other papers by Mehul Dattani in
Google Scholar
PubMed
Close
,
Diana Vitali SOD ITALIA (Italian Organization for Septo Optic Dysplasia and other Neuroendocrine Disorders), European Patient Advocacy Group, Rome, Italy

Search for other papers by Diana Vitali in
Google Scholar
PubMed
Close
,
Johan P de Graaf Dutch Pituitary Foundation, European Patient Advocacy Group, Nijkerk, The Netherlands

Search for other papers by Johan P de Graaf in
Google Scholar
PubMed
Close
, and
Nienke R Biermasz Adult Chair Main Thematic Group 6 Pituitary of Endo-ERN, Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

Search for other papers by Nienke R Biermasz in
Google Scholar
PubMed
Close

. Pituitary adenomas comprise non-hormone-producing adenomas and adenomas producing an excess of growth hormone (acromegaly), adrenocorticotropic hormone (Cushing’s disease), prolactin (prolactinoma), thyrotropin hormone (TSH-producing adenoma), and

Open access
Kunal Thakkar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Kunal Thakkar in
Google Scholar
PubMed
Close
,
Swati Ramteke-Jadhav Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Swati Ramteke-Jadhav in
Google Scholar
PubMed
Close
,
Rajeev Kasaliwal Department of Endocrinology, Mahatma Gandhi Medical College & Hospital, Jaipur, India

Search for other papers by Rajeev Kasaliwal in
Google Scholar
PubMed
Close
,
Saba Samad Memon Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Saba Samad Memon in
Google Scholar
PubMed
Close
,
Virendra Patil Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Virendra Patil in
Google Scholar
PubMed
Close
,
Puja Thadani Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Puja Thadani in
Google Scholar
PubMed
Close
,
Nilesh Lomte Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Nilesh Lomte in
Google Scholar
PubMed
Close
,
Shilpa Sankhe Department of Radiology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Shilpa Sankhe in
Google Scholar
PubMed
Close
,
Atul Goel Department of Neurosurgery, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Atul Goel in
Google Scholar
PubMed
Close
,
Sridhar Epari Department of Pathology, Tata Memorial Centre, Mumbai, India

Search for other papers by Sridhar Epari in
Google Scholar
PubMed
Close
,
Naina Goel Department of Neuropathology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Naina Goel in
Google Scholar
PubMed
Close
,
Anurag Lila Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Anurag Lila in
Google Scholar
PubMed
Close
,
Nalini S Shah Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Nalini S Shah in
Google Scholar
PubMed
Close
, and
Tushar Bandgar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

Search for other papers by Tushar Bandgar in
Google Scholar
PubMed
Close

hyperprolactinemia. Another patient (case 7) had headache, amenorrhoea, and clinical features of acromegaly. On hormonal evaluation, she had high IGF1 levels and mild hyperprolactinemia ( Table 1 ). In a recent extensive review including 69 patients with GCTs

Open access
Caiyan Mo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Caiyan Mo in
Google Scholar
PubMed
Close
,
Tao Tong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Tao Tong in
Google Scholar
PubMed
Close
,
Ying Guo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Ying Guo in
Google Scholar
PubMed
Close
,
Zheng Li Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Zheng Li in
Google Scholar
PubMed
Close
, and
Liyong Zhong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Liyong Zhong in
Google Scholar
PubMed
Close

-term overproduction of GH and IGF-1 promotes the overgrowth of soft tissues, bones, and cartilages throughout the body, leading to a series of typical signs and symptoms of acromegaly or gigantism, and can cause multi-organ/system complications such as respiratory

Open access