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), H3F3A (exon 1), IDH1 (exon 4), IDH2 (exon 4), MED12 (exon 2), c-Kit (exons 8, 9, 11, 13, 17), MET (exon 2, 14), c-Myc (exons 1, 2, 3), PDGRα (exons 12, 14, 18), PIK3CA (exons 10, 21), PTEN (exon 5), RET (exons 5, 8, 10, 11, 13
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of low-dose bisphenol a on dna damage and proliferation of breast cells: the role of c-Myc . Environmental Health Perspectives 2015 123 1271 – 1279 . ( https://doi.org/10.1289/ehp.1409199s )
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, including ganglioneuroma (GN), neuroblastoma, ganglioneuroblastoma, etc ( 1 , 2 ). Currently, little is known about its pathogenesis and relationship with its pure tumor counterparts. Comstock et al. investigated the N- myc amplification status in CP
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. Comparative genomic hybridization (CGH) of the GNEN-1 cell line CGH performed with extracted DNA from the cell line revealed a chaotic structure of the chromosomes. The main findings were amplification of 8q24.21 where the MYC gene is located and
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FoxO3a to hamper the expression of Atrogin1 and MuRF1 and (2) SGK-1 and its substrate, N-myc downstream-regulated gene 1 (NDRG1), block Smad2/3 activation in muscle cells ( 40 , 41 , 42 ). The expression and activity of muscle SGK1 is susceptible to
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D), MAX (MYC-associated factor X), NF1 (neurofibromin 1), RET (rearranged during transfection), VHL , FH (fumarate hydratase), FLCN (folliculin), and MET using Target Capture-Based Deep Sequencing (BGI Health, Shenzhen, Guangdong, China
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