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methods and environmental risk factors such as obesity ( 3 , 4 , 5 , 6 ). Papillary thyroid carcinoma can occur multifocally, with about 30% corresponding to microcarcinomas (tumor diameter ≤ 1 cm), and most metastases arise in regional lymph nodes
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina
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Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, Córdoba, Argentina
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Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina
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Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina
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Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Haya de la Torre y Medina Allende, Ciudad Universitaria, Córdoba (X5000HUA), Argentina
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MMPs was evaluated by zymography. Co-cultures of Fb, thyroid tumor and non-tumor cells Fb (600,000 cells) and human thyroid tumor (TPC-1 or 8505c) or non-tumor (NThyOri) cells (600,000 cells) were mixed and plated together in 100-mm-diameter
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HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland
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surgical cholecystectomy. Ultrasound imaging revealed an incidental finding of multiple liver metastases. No primary tumor was visualized in a full-body CT scan. Gastroscopy revealed an approximately 1-cm diameter mass with necrotic center at the border
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tumor and LNM. Indeed, when the size of the largest metastatic focus of LNM was ≥0.65 cm, the BRAF V600E mutation frequency was lower. In contrast, Kurtulmus et al. showed that BRAF V600E-positive metastatic lymph nodes were greater in diameter than
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Hormonology Department, Cochin Hospital, Paris, France
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Radiology Department, Cochin Hospital, Paris, France
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Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France
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Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France
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Hormonology Department, Cochin Hospital, Paris, France
INSERM, Physiopathologie et Pharmacotoxicologie Placentaire Humaine : Microbiote Pré & Post natal, Paris, France
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Diabetology Department, Cochin Hospital, Paris, France
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Hormonology Department, Cochin Hospital, Paris, France
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UR 7537 BioSTM, Paris, France
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a form of bilateral benign adrenocortical tumors, responsible for hypercortisolism of progressive installation, often diagnosed between 40 and 65 years and characterized by the presence of bilateral macronodules (diameter >1 cm) on imaging
Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
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somatostatinoma. The median tumor diameter of the whole cohort was 2.7 cm (IQR 1.5–4.0 cm) and only seven patients (4.0%) harbored multiple primary lesions. According to the WHO criteria, 73 cases (42.0%) were classified as G1, 88 (50.6%) were G2 and 13 (7
PhD School of Clinical and Experimental Biomedical Sciences, University of Messina, Messina, Sicily, Italy
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Department of Human Pathology ‘G. Barresi’, University of Messina, Messina, Sicily, Italy
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‘invasive’ or ‘aggressive’ ( 1 ). Moreover, the term ‘giant’ adenoma is usually applied to those tumors exceeding 40 mm in maximum diameter ( 2 ). In PT patients, multimodal treatment, including neurosurgery, drugs and radiotherapy, is generally effective
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diagnosed at any time with a pituitary adenoma were eligible, up to a cut-off date of July 2017. Data on each patient included sex, date of birth, age at diagnosis, tumor size (maximum diameter), tumor classification (micro-or macroadenomas), treatment
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/Akt/mTOR pathway and CCND1 /cyclin D1 amplifications are also potentially driver events in PC ( 2 ). PC may occur in the context of genetic syndromes in up to 15% of patients with hyperparathyroidism-jaw tumor (HPT‐JT; CDC73/HRPT2 gene), 1% of familial isolated
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Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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were noted for local (including small benign insulinomas ∼12 mm diameter) or metastatic tumors (including liver and bone deposits). In particular, the use of SSAs was not associated with a negative test; all SSA-treated patients exhibited a positive PCR