Search for other papers by Yuan Huang in
Google Scholar
PubMed
Search for other papers by Yunyun Hu in
Google Scholar
PubMed
Search for other papers by Bingshu Bao in
Google Scholar
PubMed
ineffectiveness in estimating fat distribution and differentiating between muscle/fat mass ( 6 , 14 ). BMI is more suitable for general-obesity assessment ( 15 ). A central fat-related biomarker, visceral adipose tissue (VAT), has emerged as a good remedy for the
Search for other papers by Hong-Fa Yan in
Google Scholar
PubMed
Search for other papers by Zhao-Yu Liu in
Google Scholar
PubMed
Search for other papers by Zhi-Ang Guan in
Google Scholar
PubMed
Search for other papers by Chuang Guo in
Google Scholar
PubMed
, 36 ). It has been reported that, in murine models, iron-enriched diets decrease adipocyte insulin sensitivity and are associated with visceral adipose tissue hyperplasia and hypertrophy; however, iron-restricted diets lead to opposite effects ( 16
Search for other papers by Michaela Keuper in
Google Scholar
PubMed
adipocytes . Diabetes 2004 53 . ( https://doi.org/10.2337/diabetes.53.5.1285 ) 15111498 40 Curat CA Wegner V Sengenès C Miranville A Tonus C Busse R Bouloumié A . Macrophages in human visceral adipose tissue: increased accumulation in
Search for other papers by Nese Cinar in
Google Scholar
PubMed
Search for other papers by Alper Gurlek in
Google Scholar
PubMed
in visceral (epididymal) and subcutaneous (inguinal) adipose tissues, while ADP mRNA expression was downregulated by T 3 in the subcutaneous adipose tissue, but not in the visceral adipose tissue (VAT). The authors suggest that ADP mRNA response to T
Search for other papers by Philippe Jean-Luc Gradidge in
Google Scholar
PubMed
Search for other papers by Nicole G Jaff in
Google Scholar
PubMed
Global Health Research Institute, School of Human Development and Health, University of Southampton, Southampton, UK
Search for other papers by Shane A Norris in
Google Scholar
PubMed
Search for other papers by Marketa Toman in
Google Scholar
PubMed
Search for other papers by Nigel J Crowther in
Google Scholar
PubMed
distribution rather than total body adiposity ( 8 ) has been associated with differing levels of cardiometabolic disease (CMD) risk. Thus, studies have shown that an accumulation of visceral adipose tissue increases the risk of CMD ( 9 ), while the deposition
Search for other papers by Antonia Ertelt in
Google Scholar
PubMed
Search for other papers by Ann-Kristin Barton in
Google Scholar
PubMed
Search for other papers by Robert R Schmitz in
Google Scholar
PubMed
Search for other papers by Heidrun Gehlen in
Google Scholar
PubMed
localizations of adipose tissue, lipogenesis differs at various fat depots (30, 31, 32) . There are also differences in gene expression in visceral and subcutaneous fat in humans; however, isolated and cultured human preadipocytes are still capable of their
Division of Exercise Science and Sport Medicine, Department of Human Biology, University of Cape Town, 3 Floor Sports Science Institute of South Africa Cape Town, South Africa
Search for other papers by Julia H Goedecke in
Google Scholar
PubMed
Search for other papers by Mehreen Tootla in
Google Scholar
PubMed
Search for other papers by Dheshnie Keswell in
Google Scholar
PubMed
comprises both visceral (VAT) and subcutaneous adipose tissue (SAT), is commonly associated with increased cardiometabolic risk, whereas lower-body gluteo-femoral fat accumulation may be protective ( 4 , 5 ). Within adipose tissue, aromatase ( CYP19A1
Search for other papers by Leanne Hodson in
Google Scholar
PubMed
Search for other papers by Fredrik Karpe in
Google Scholar
PubMed
insulin resistant (B). In the fasting state non-esterified fatty acids (NEFA) from the lipolysis of subcutaneous and visceral adipose tissue enter the liver and mix with fatty acids (FAs) from the cytosolic triacylglycerol (TAG) storage pool and those from
Search for other papers by Florian W Kiefer in
Google Scholar
PubMed
pheochromocytoma, significant FDG uptake has also been detected in visceral adipose tissue reflecting a browning of this WAT compartment due to the prolonged stimulation with endogenous catecholamines ( 35 , 36 ). However, after surgical removal of the tumor, FDG
Search for other papers by Erika Peverelli in
Google Scholar
PubMed
Endocrinology and Diabetology Unit, Diabetology and Metabolic Disease Unit, Endocrinology Unit, Unit of Human Pathology, Surgical Department, Department of Clinical Sciences and Community Health, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pad.Granelli, Via F. Sforza, 35, 20122 Milan, Italy
Search for other papers by Federica Ermetici in
Google Scholar
PubMed
Search for other papers by Sabrina Corbetta in
Google Scholar
PubMed
Search for other papers by Ettore Gozzini in
Google Scholar
PubMed
Search for other papers by Laura Avagliano in
Google Scholar
PubMed
Search for other papers by Marco A Zappa in
Google Scholar
PubMed
Search for other papers by Gaetano Bulfamante in
Google Scholar
PubMed
Search for other papers by Paolo Beck-Peccoz in
Google Scholar
PubMed
Search for other papers by Anna Spada in
Google Scholar
PubMed
Search for other papers by Giovanna Mantovani in
Google Scholar
PubMed
12 and 14 weeks and the absence of PRKAR1A. Visceral adipose tissue almost entirely composed of mature adipocytes, as indicated by the negative staining for Pref1, as well as a subcutaneous adipose layer, was present in the tissue sections of 36-week