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Leanne Hodson Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford and National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford University Hospital Trusts, Oxford, UK

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Fredrik Karpe Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford and National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Oxford University Hospital Trusts, Oxford, UK

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and fatty acid removal (via oxidation or export as triacylglycerol (TAG)) from the liver. Pathological accumulation of intra-hepatocellular TAG (IHTAG) is denoted as nonalcoholic liver disease (NAFLD), which encompasses a spectrum of conditions from

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0350
Volume/Issue:
Volume 8: Issue 10
Open access
Stephen J Winters Division of Endocrinology, Metabolism and Diabetes, University of Louisville, Louisville, Kentucky, USA

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Charles R Scoggins Division of Surgical Oncology, University of Louisville, Louisville, Kentucky, USA

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Duke Appiah Department of Public Health, Texas Tech University Health Sciences Center, Lubbock, Texas, USA

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Dushan T Ghooray Division of Endocrinology, Metabolism and Diabetes, University of Louisville, Louisville, Kentucky, USA

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. ( https://doi.org/10.1042/bj1610431 ) 29 Luo J Chen Q Shen T Wang X Fang W Wu X Yuan Z Chen G Ling W Chen Y Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults . Nutrition and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0401
Volume/Issue:
Volume 9: Issue 10
Open access
Tatsuya Kondo Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan

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Nobukazu Miyakawa Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Sayaka Kitano Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan

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Takuro Watanabe Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Rieko Goto Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Mary Ann Suico Department of Molecular Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Miki Sato Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Yuki Takaki Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Masaji Sakaguchi Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Motoyuki Igata Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan

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Junji Kawashima Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Hiroyuki Motoshima Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Takeshi Matsumura Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Hirofumi Kai Department of Molecular Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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Eiichi Araki Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan

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diabetes-associated nonalcoholic fatty liver disease . Journal of Clinical and Experimental Hepatology 2019 9 607 – 618 . ( https://doi.org/10.1016/j.jceh.2018.10.004 ) 3 Kadowaki S Tamura Y Someya Y Takeno K Kaga H Sugimoto D Kakehi

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0084
Volume/Issue:
Volume 10: Issue 5
Open access
Xiaonan Guo Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Wenjing Hu Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Xiaorui Lyu Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Hanyuan Xu Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Huijuan Zhu Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Hui Pan Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Linjie Wang Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Hongbo Yang Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Fengying Gong Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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secondary deficiency of IGF-1 ( 1 ). Several studies have shown that congenital GHD is associated with an increased risk of metabolic syndromes, such as nonalcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and hyperlipidemia ( 4

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-23-0462
Volume/Issue:
Volume 13: Issue 5
Open access
Till Ittermann Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Rehman Mehmood Khattak Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
Department of Zoology, Islamia College Peshawar (CU), Peshawar, Pakistan

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Marcello R P Markus Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany

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Jens-Peter Kühn Institute of Radiology, University Hospital, Carl-Gustav-Carus University, Dresden, Germany

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Marie-Luise Kromrey Department of Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany

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Giovanni Targher Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, Verona, Italy

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Antje Steveling Department of Internal Medicine A, University Medicine Greifswald, Greifswald, Germany

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Matthias Nauck Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine, Greifswald, Germany

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Henry Völzke Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Introduction Non-alcoholic fatty liver disease (NAFLD) is a common finding in individuals with obesity or type 2 diabetes mellitus and its prevalence is steeply increasing worldwide ( 1 ). Recent meta-analyses of observational studies revealed

Article Type:
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Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-21-0566
Volume/Issue:
Volume 11: Issue 2
Open access
Frederique Van de Velde Department of Endocrinology, Ghent University Hospital, Ghent, Belgium

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Marlies Bekaert Department of Endocrinology, Ghent University Hospital, Ghent, Belgium

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Anja Geerts Department of Hepatology, Ghent University Hospital, Ghent, Belgium

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Anne Hoorens Department of Pathology, Ghent University Hospital

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Arsène-Hélène Batens Department of Endocrinology, Ghent University Hospital, Ghent, Belgium

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Samyah Shadid Department of Endocrinology, Ghent University Hospital, Ghent, Belgium

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Margriet Ouwens Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Duesseldorf, Germany
German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany

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Yves Van Nieuwenhove Department of Gastrointestinal Surgery, Ghent University Hospital, Ghent, Belgium

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Bruno Lapauw Department of Endocrinology, Ghent University Hospital, Ghent, Belgium

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Introduction An important complication of obesity is the development of nonalcoholic fatty liver disease (NAFLD), which covers a broad histological spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH), and can progress to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0366
Volume/Issue:
Volume 8: Issue 9
Open access
Helle Keinicke Insulin and Device Trial Operations, Novo Nordisk A/S, Søborg, Denmark

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Gao Sun Pharmacology and Histopathology, Novo Nordisk A/S, China

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Caroline M Junker Mentzel Department of Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Merete Fredholm Department of Veterinary Clinical and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Linu Mary John Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Birgitte Andersen Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Kirsten Raun Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Marina Kjaergaard Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Introduction Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in the Western world ( 1 , 2 ) with a global prevalence of 25% ( 3 ). It is defined as steatosis (fat accumulation) in at least 5% of hepatocytes ( 3

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DOI:
https://doi.org/10.1530/EC-20-0152
Volume/Issue:
Volume 9: Issue 8
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Rachel D C A Diniz
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Renata M Souza
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Roberto Salvatori Division of Endocrinology, Division of Endocrinology, Division of Hepatology, Division of Radiology, Diabetes and Metabolism, Federal University of Sergipe, Aracaju, Brazil

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Alex Franca Division of Endocrinology, Division of Endocrinology, Division of Hepatology, Division of Radiology, Diabetes and Metabolism, Federal University of Sergipe, Aracaju, Brazil

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Elenilde Gomes-Santos
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Thiago O Ferrão Division of Endocrinology, Division of Endocrinology, Division of Hepatology, Division of Radiology, Diabetes and Metabolism, Federal University of Sergipe, Aracaju, Brazil

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Carla R P Oliveira
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João A M Santana
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Francisco A Pereira
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Rita A A Barbosa
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Anita H O Souza
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Rossana M C Pereira
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Alécia A Oliveira-Santos
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Allysson M P Silva
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Francisco J Santana-Júnior
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Eugênia H O Valença
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Viviane C Campos
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Manuel H Aguiar-Oliveira
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Introduction Nonalcoholic fatty liver disease (NAFLD) is a manifestation of the metabolic syndrome and is associated with very common conditions such as obesity, type 2 diabetes, hypertension, dyslipidemia, and atherosclerosis (1) . NAFLD includes

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DOI:
https://doi.org/10.1530/EC-14-0078
Volume/Issue:
Volume 3: Issue 3
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Xu Chen Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China
Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China

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Yi Tang Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China

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Shen Chen Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China

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Wenhua Ling Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China

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Qing Wang Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China

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Introduction Non-alcoholic fatty liver disease (NAFLD), which is considered to be the hepatic manifestation of the metabolic syndrome is defined as the abnormal hepatic triglyceride (TG) accumulation without excessive alcohol use. NAFLD

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Research Article
DOI:
https://doi.org/10.1530/EC-21-0353
Volume/Issue:
Volume 10: Issue 10
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Panagiotis Anagnostis Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

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Irene Lambrinoudaki 2nd Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Medical School, Athens, Greece

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John C Stevenson National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield Hospitals, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

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Dimitrios G Goulis Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

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, atherogenic dyslipidemia, glucose intolerance, arterial hypertension (AH) and non-alcoholic fatty liver disease (NAFLD), compared with premenopausal status ( 5 ). In detail, transition to menopause leads to body fat redistribution toward the male pattern of

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Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-21-0537
Volume/Issue:
Volume 11: Issue 4
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