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demonstrated in different NETs including pituitary adenomas, GEP-NETs, pheochromocytomas and paragangliomas, neuroblastoma, Merkel cell carcinoma and medullary thyroid carcinoma ( 38 ). Most previous studies have focused on membrane expression. We recently
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experimental model to study human neuroblastoma . Journal of Cellular Physiology 2018 234 152 – 157 . ( https://doi.org/10.1002/jcp.26773 ) 19 Staton CA Reed MW Brown NJ . A critical analysis of current in vitro and in vivo angiogenesis assays
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cancer ( 21 ). Interestingly, loss of ATF2 function has also been observed in other malignancies, such as breast and lung carcinomas as well as neuroblastoma ( 22 ), implying that the balance of tissue-specific compositions of ATF2-AP1 dimers is critical
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retinoblastoma and neuroblastoma cell lines Y79 and IMR-32 (see ( 9 ) for references). Desensitization was also found dependent on specific ligands activating CRHRs ( 135 ). CRH and UCN1 differential regulation of CRHR1 recycling and resensitization has been
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tumours at 5, 10 and 20 years are 95.8, 95.8 and 71%, respectively ( 3 ). Table 3 Youngest diagnosis with SDHB- related tumours. Site of PPGL Age at diagnosis (years) References Adrenal neuroblastoma 5 ( 22
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, neuroblastoma, soft tissue sarcoma), children with malignant brain tumours more frequently receive surgery and cranial radiation, and traditionally chemotherapy has been used sparingly. It is important, therefore, to establish the impact of the different disease