Jia Li
Jia Li
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
Department of Electronic Science, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, China
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Department of Electronic Science, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, China
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Yan Zhao
Yan Zhao
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Caoxin Huang
Caoxin Huang
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Zheng Chen
Zheng Chen
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Xiulin Shi
Xiulin Shi
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Long Li
Long Li
Institute of Drug Discovery Technology, Ningbo University, Ningbo, China
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Zhong Chen
Zhong Chen
Department of Electronic Science, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, China
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Xuejun Li
Xuejun Li
Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, Xiamen, China
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exercise using untargeted ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) technology. Altered metabolites and metabolic pathways are established and may help explain the mechanism underlying
Paal Methlie
Paal Methlie
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Steinar Hustad
Steinar Hustad
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Ralf Kellman
Ralf Kellman
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Bjørg Almås
Bjørg Almås
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Martina M Erichsen
Martina M Erichsen
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Eystein S Husebye
Eystein S Husebye
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Kristian Løvås
Kristian Løvås
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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Department of Clinical Science, Department of Medicine, University of Bergen, N-5021 Bergen, Norway
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's syndrome (CS) and congenital adrenal hyperplasia, male hypogonadism and female hyperandrogenism. Although immunoassays have largely been used to measure steroid hormones, over the last decade, mass spectrometry (MS) has increasingly been adopted as it
T P Parikh
T P Parikh
Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA
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B Stolze
B Stolze
Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA
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Y Ozarda
Y Ozarda
Department of Medical Biochemistry, Faculty of Medicine, Uludag University, Bursa, Turkey
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J Jonklaas
J Jonklaas
Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA
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K Welsh
K Welsh
Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA
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L Masika
L Masika
Department of Laboratory Medicine and Pathology/National Health Laboratory Service Walter Sisulu University, Mthatha, South Africa
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M Hill
M Hill
Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA
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A DeCherney
A DeCherney
Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA
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S J Soldin
S J Soldin
Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA
Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA
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Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA
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of high-performance liquid chromatography (HPLC) in conjunction with tandem mass spectrometry (MS) is increasingly becoming the method of choice for clinical testing of hormone levels ( 5 , 6 , 15 , 16 , 17 ). Given its high sensitivity
Jean-Benoît Corcuff
Jean-Benoît Corcuff
Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France
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Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France
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Laurence Chardon
Laurence Chardon
Department of Biochemistry, Edouard Herriot Hospital, Lyon, France
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Ines El Hajji Ridah
Ines El Hajji Ridah
Biomnis, Lyon, France
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Julie Brossaud
Julie Brossaud
Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France
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Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France
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electrochemical detection ( 18 , 19 , 20 ). Recently, liquid chromatography coupled to mass spectrometry has been used for the detection and quantification of urinary as well as serum 5HIAA ( 21 , 22 , 23 ). Obviously, these last 5HIAA assays after HPLC
Muriel Houang
Muriel Houang
Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
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Thao Nguyen-Khoa
Thao Nguyen-Khoa
Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France
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Thibaut Eguether
Thibaut Eguether
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Bettina Ribault
Bettina Ribault
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Séverine Brabant
Séverine Brabant
Laboratoire d’Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France
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Michel Polak
Michel Polak
Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France
Université de Paris, INSERM, Institut IMAGINE, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
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Université de Paris, INSERM, Institut IMAGINE, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
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Irène Netchine
Irène Netchine
Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
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Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
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Antonin Lamazière
Antonin Lamazière
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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was eventually positively diagnosed thanks to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), which allowed the quantitation of endogenous steroid metabolites and the identification of exogenous glucocorticoid treatment on a
Johanna Christina Penell
Johanna Christina Penell
Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Mark M Kushnir
Mark M Kushnir
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
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ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
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Lars Lind
Lars Lind
Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden
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Jonatan Bergquist
Jonatan Bergquist
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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Jonas Bergquist
Jonas Bergquist
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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P Monica Lind
P Monica Lind
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Tord Naessen
Tord Naessen
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
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concentrations seen in elderly ( 25 , 26 , 27 ). We recently developed highly sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods to identify and quantify a large number of steroids in small sample volumes ( 13 , 14 , 16
Run-Qing Xiong
Run-Qing Xiong
Department of Ultrasonic Imaging, Xiamen Medical College Affiliated Second Hospital, Fujian, China
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Yan-Ping Li
Yan-Ping Li
Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China
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Lu-Ping Lin
Lu-Ping Lin
Department of Endocrinology, Xiamen Medical College Affiliated Second Hospital, Fujian, China
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Jeng-Yuan Yao
Jeng-Yuan Yao
Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China
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-segment changes in some leads, T-wave changes in some leads, and low voltage in the left chest lead. The purpose of this study was to examine the distinct metabolite profiles of plasma among these groups using liquid chromatography–mass spectrometry (LC-MS) to
Niek F Dirks
Niek F Dirks
Atalmedial Diagnostics Centre, Spaarne Gasthuis, Haarlem, The Netherlands
Department of Clinical Chemistry, Hematology and Immunology, Noordwest Ziekenhuis, Alkmaar, The Netherlands
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Department of Clinical Chemistry, Hematology and Immunology, Noordwest Ziekenhuis, Alkmaar, The Netherlands
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Etienne Cavalier
Etienne Cavalier
Department of Clinical Chemistry, University of Liège, CHU de Liège, Liège, Belgium
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Annemieke C Heijboer
Annemieke C Heijboer
Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Clinical Chemistry, Endocrine Laboratory, Boelelaan, Amsterdam, The Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam UMC location University of Amsterdam, Department of Clinical Chemistry, Endocrine Laboratory, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam UMC location University of Amsterdam, Department of Clinical Chemistry, Endocrine Laboratory, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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always the same for every method designed to measure vitamin D. Second, knowing the pitfalls of the used assay, most often an automated immunoassay or a liquid-chromatography coupled to tandem mass-spectrometry, is important for the interpretation of the
Amalie Carlsson
Amalie Carlsson
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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Kaspar Sørensen
Kaspar Sørensen
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
The Child and Youth Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The Child and Youth Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Anna-Maria Andersson
Anna-Maria Andersson
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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Hanne Frederiksen
Hanne Frederiksen
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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one out of nine environmental phenols measured by liquid chromatography-tandem mass spectrometry (LC–MS/MS) with prior enzymatic deconjugation ( 19 , 20 ). For the present study, first morning urine collected from the first of the two consecutive
M P Schuijt
M P Schuijt
Department of Laboratory Medicine, Slingeland Hospital, Doetinchem, The Netherlands
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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C G J Sweep
C G J Sweep
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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R van der Steen
R van der Steen
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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A J Olthaar
A J Olthaar
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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N M M L Stikkelbroeck
N M M L Stikkelbroeck
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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H A Ross
H A Ross
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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A E van Herwaarden
A E van Herwaarden
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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chromatography tandem mass spectrometry (ED-LC-MS/MS). LC-MS/MS enables the accurate, specific and matrix-independent measurement of testosterone with direct calibration. Equilibrium dialysis enables to separate the free- from protein-bound testosterone with
