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2.2 CSOM230B2219 ( 9 ) 20 39 M N Y N Octreotide LAR + cabergoline 3.4 CSOM230B2219 ( 9 ) Bold indicates late responders (after ≥4 months of treatment). a Defined as baseline glucose ≥ 126 mg/dL, HbA1c ≥ 6
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Introduction Prenatal and early postnatal malnutrition can mediate metabolic programming with life-lasting effects. This represents a risk for development of metabolic diseases later in life, such as obesity and type 2 diabetes ( 1 , 2 , 3
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Emma Children’s Hospital, Amsterdam UMC, Department of Pediatrics, Amsterdam, The Netherlands
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University Hospital Würzburg, Department of Nuclear Medicine, Würzburg, Germany
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2018, the International Guideline Harmonization Group (IGHG) on guidelines for late effects of childhood cancer, therefore, released recommendations on surveillance for DTC in at-risk CCS ( 6 ). These guidelines stated that surveillance for DTC may be
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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blood work done. Adverse events were registered at every visit, and participants were instructed to contact the investigators if they experienced any adverse effects. Assays Thrombin generation was assessed with a Calibrated Automated Thrombogram
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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chosen in Europe as it is mostly well-tolerated. However, there are well-known side effects. Most feared is agranulocytosis, but other potential side effects include hepatotoxicity, loss of taste, arthralgia and most commonly rash, which can be severe. As
Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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to contribute to increasing maternal circulating glucose during murine pregnancy ( 8 ). These prolactin-related peptides are, however, unlikely to have the same effects as GH, since in mouse prolactin and GH bind poorly to each other’s receptors ( 9
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Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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high prenatal cortisol exposure on child development. The effects of synthetic GC administration and maternal stress on later neurodevelopmental disorders have been reviewed elsewhere ( 52 , 73 , 74 ). In sum, both prenatal synthetic GCs and naturally
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review articles that relate to paediatric elements of disease and, as an example of this initiative, we are currently publishing an excellent series of articles on the ‘Late effects of cancer therapy in children’ ( https
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U. Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters . Reproduction 2014 147 465 – 476 . ( https://doi.org/10.1530/REP-13-0448 ) 10.1530/REP-13-0448 24287426 9 Jarfelt K
Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
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's syndrome) (1, 2, 3, 4, 5, 6, 7) . It is now accepted that an increased late-night salivary cortisol (at the circadian nadir) has 90–95% sensitivity and specificity for the diagnosis of Cushing's syndrome (6, 7) . In patients with normal renal function