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signalling pathways, which lead to the deficiency of pancreatic cells ( 9 ). Interleukin (IL)-34 is a recently discovered pro-inflammatory cytokine that is composed of 242 amino acids ( 10 ). Moreover, IL-34 can bind with the extracellular domain of colony
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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(TNFα) concentrations (A), interleukin 6 (IL-6) concentrations (B), axillary temperature (C), heart rate (D), symptom score (E) and mean arterial blood pressure (F) before (t = 0) and after (t = 60, 120, 180, 240, 300, 360) systemic LPS exposure in young
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released in LCH lesions lead to local amplification cascades of cellular proliferation and activation through autocrine and paracrine stimulatory pathways ( 13 ). Granulocyte/macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1) and tumor
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glucose was considered as <200 mg/dL. Patients without previously known diabetes and random plasma glucose ≥200 mg/dL were labeled as ‘new-onset hyperglycemia’. The interleukin-6 (IL6) assay was done by chemiluminescent immunoassay (Siemens Advia Centaur
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Center for Clinical Research and Prevention, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmark
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) and interleukin (IL)-6. Animal and human studies have shown association between low testosterone concentrations and higher pro-inflammatory cytokines (e.g. IL-6) and lower anti-inflammatory cytokines (e.g. IL-10), and thus, low testosterone
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-HR(2), Wako Chemicals GmbH, Germany) were analysed with the above standing methods and were all performed in accordance with the manufacturer’s recommendations. Serum concentrations of tumour necrosis factor alpha (TNF-α), interleukin (IL)-6 and IL-10
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Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Sweden
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radioligand binding assay in 2 patients ( 23 ). Antibodies to glutamic acid decarboxylase (GAD), tyrosine phosphatase (IA2), 21-hydroxylase (21-OH), interleukin-22 (IL-22), side-chain cleavage (SSC), tryptophan hydroxylase (TPH), cytochrome P4501A2 (CYP1A2
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monocyte and macrophage-derived interleukin 6 (IL-6), induce a non-osmotic vasopressin release ( 11 , 12 ). In predisposed individuals infected by the novel coronavirus SARS-CoV-2, IL-6 is also the main actor implied in the 'cytokine storm', which causes
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, 14 , 15 ), and recent studies have reported inverse correlations between thyroid stimulating hormone (TSH) and interleukin 6 (IL-6) in patients with COVID-19 ( 6 , 9 , 16 ). Thus, this study aimed to evaluate thyroid hormone involvement in the
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Institute of Oncology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Mao C Mou X Wu F Wang X Bu L Zhou Y Luo X Lu Q , et al . Increased interleukin-23 in Hashimoto’s thyroiditis disease induces autophagy suppression and reactive oxygen species accumulation . Frontiers in Immunology 2018 9 96