Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
Search for other papers by Christos Tsatsanis in
Google Scholar
PubMed
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
Search for other papers by Angel Elenkov in
Google Scholar
PubMed
Search for other papers by Irene Leijonhufvud in
Google Scholar
PubMed
Search for other papers by Katerina Vaporidi in
Google Scholar
PubMed
Search for other papers by Åsa Tivesten in
Google Scholar
PubMed
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
Search for other papers by Aleksander Giwercman in
Google Scholar
PubMed
immune responses and susceptibility to autoimmunity and inflammatory diseases. B-cell activating factor (BAFF) also known as tumor necrosis factor (TNF) ligand superfamily member 13B is a cytokine of the TNF family that is causally linked to the
Search for other papers by Frans H H Leenen in
Google Scholar
PubMed
Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
Search for other papers by Mordecai P Blaustein in
Google Scholar
PubMed
Search for other papers by John M Hamlyn in
Google Scholar
PubMed
direct neuronal actions, Ang II/AT 1 R can also activate microglia to generate proinflammatory cytokines, which in nuclei such as the PVN contribute to ROS production and downstream sympatho-excitatory and pressor responses ( 7 , 8 ). Active renin is
Search for other papers by Emanuela Zaharieva in
Google Scholar
PubMed
Search for other papers by Zdravko Kamenov in
Google Scholar
PubMed
Search for other papers by Tsvetelina Velikova in
Google Scholar
PubMed
Search for other papers by Adelina Tsakova in
Google Scholar
PubMed
Search for other papers by Yosif El-Darawish in
Google Scholar
PubMed
Search for other papers by Haruki Okamura in
Google Scholar
PubMed
Introduction Interleukin-18 (IL-18), discovered in the late 20th century as an interferon-gamma (IFNγ)-inducing factor ( 1 ), is a cytokine that belongs to the IL-1 superfamily ( 2 ). It is produced by monocyte/macrophages, endothelial cells
Search for other papers by Chenghao Piao in
Google Scholar
PubMed
Search for other papers by Xiaojie Wang in
Google Scholar
PubMed
Search for other papers by Shiqiao Peng in
Google Scholar
PubMed
Search for other papers by Xinyu Guo in
Google Scholar
PubMed
Search for other papers by Hui Zhao in
Google Scholar
PubMed
Search for other papers by Li He in
Google Scholar
PubMed
Search for other papers by Yan Zeng in
Google Scholar
PubMed
Search for other papers by Fan Zhang in
Google Scholar
PubMed
Search for other papers by Kewen Zhu in
Google Scholar
PubMed
Search for other papers by Yiwei Wang in
Google Scholar
PubMed
of pancreatic β cells is correlated with the pathogenesis of GDM. A significant association between GDM and inflammation has been reported ( 8 ). Highly secreted pro-inflammatory cytokines, such as IL-6, TNF-α and IL-1 β, contribute to the insulin
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Search for other papers by Natalio García-Honduvilla in
Google Scholar
PubMed
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
Search for other papers by Alberto Cifuentes in
Google Scholar
PubMed
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
Search for other papers by Miguel A Ortega in
Google Scholar
PubMed
Search for other papers by Marta Pastor in
Google Scholar
PubMed
Search for other papers by Garazi Gainza in
Google Scholar
PubMed
Search for other papers by Eusebio Gainza in
Google Scholar
PubMed
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Search for other papers by Julia Buján in
Google Scholar
PubMed
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Immune System Diseases-Rheumatology and Oncology Service, University Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
Search for other papers by Melchor Álvarez-Mon in
Google Scholar
PubMed
results are expressed as mean number of positive cells/field. Real-time PCR The expression of several key cytokines in the wound tissue was measured by quantitative real-time PCR. Total RNA was isolated from skin frozen samples of animals from
Search for other papers by Wenrui Wang in
Google Scholar
PubMed
Search for other papers by Chuan Zhang in
Google Scholar
PubMed
non-β-cells; hepatic and biliary cells; gastrointestinal cells into β-cells through genetic programming; cytokines; and small molecules. These cells comprise the leading candidates because of their common endodermal origin with β-cells, abundant
Search for other papers by Anna C Simcocks in
Google Scholar
PubMed
School of Science and Health, Western Sydney University, Campbelltown, New South Wales, Australia
Search for other papers by Kayte A Jenkin in
Google Scholar
PubMed
Search for other papers by Lannie O’Keefe in
Google Scholar
PubMed
Search for other papers by Chrishan S Samuel in
Google Scholar
PubMed
The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, Victoria, Australia
Search for other papers by Michael L Mathai in
Google Scholar
PubMed
Australian Institute for Musculoskeletal Science (AIMSS), College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia
Search for other papers by Andrew J McAinch in
Google Scholar
PubMed
School of Environment and Sciences, Griffith University, Nathan, Queensland, Australia
Search for other papers by Deanne H Hryciw in
Google Scholar
PubMed
), vascular endothelial growth factor (VEGF) and interleukin 13 (IL-13) were analyzed in accordance with manufacturer’s instructions (Bioplex cytokine assay; Bio-Rad Laboratories). A number of samples within each group were out of range for some of the
Search for other papers by Yongping Liu in
Google Scholar
PubMed
Search for other papers by Shuo Wang in
Google Scholar
PubMed
Search for other papers by Qingling Guo in
Google Scholar
PubMed
Search for other papers by Yongze Li in
Google Scholar
PubMed
Search for other papers by Jing Qin in
Google Scholar
PubMed
Search for other papers by Na Zhao in
Google Scholar
PubMed
Search for other papers by Yushu Li in
Google Scholar
PubMed
Search for other papers by Zhongyan Shan in
Google Scholar
PubMed
Search for other papers by Weiping Teng in
Google Scholar
PubMed
increased T cells and natural killer (NK) cells, as well as the pro-inflammatory cytokine secretion of T cells and NK cells, were observed after stimulation with soluble Sema 5A ( 26 ). Another study identified an elevated Sema 5A expression of mRNA in
Search for other papers by Simon Schimmack in
Google Scholar
PubMed
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
Search for other papers by Yongchao Yang in
Google Scholar
PubMed
Search for other papers by Klaus Felix in
Google Scholar
PubMed
Search for other papers by Markus Herbst in
Google Scholar
PubMed
Search for other papers by Yixiong Li in
Google Scholar
PubMed
Search for other papers by Miriam Schenk in
Google Scholar
PubMed
Search for other papers by Frank Bergmann in
Google Scholar
PubMed
Search for other papers by Thilo Hackert in
Google Scholar
PubMed
Search for other papers by Oliver Strobel in
Google Scholar
PubMed
the secretion of pro-inflammatory cytokines enhancing inflammatory response ( 14 , 15 ). Another protein that is involved in response to inflammatory products is STAT3 (signal transducer and activator of transcription 3). It is a crucial regulator
Search for other papers by Jiayang Lin in
Google Scholar
PubMed
Search for other papers by Peizhen Zhang in
Google Scholar
PubMed
Search for other papers by Yan Huang in
Google Scholar
PubMed
Search for other papers by Xueyun Wei in
Google Scholar
PubMed
Search for other papers by Dan Guo in
Google Scholar
PubMed
Search for other papers by Jianfang Liu in
Google Scholar
PubMed
Search for other papers by Deying Liu in
Google Scholar
PubMed
Search for other papers by Yajuan Deng in
Google Scholar
PubMed
Search for other papers by Bingyan Xu in
Google Scholar
PubMed
Search for other papers by Chensihan Huang in
Google Scholar
PubMed
Search for other papers by Xiaoyu Yang in
Google Scholar
PubMed
Search for other papers by Yan Lu in
Google Scholar
PubMed
Search for other papers by Lijing Jia in
Google Scholar
PubMed
Search for other papers by Huijie Zhang in
Google Scholar
PubMed
, increased lipolysis, and hepatic gluconeogenesis ( 7 , 8 , 9 ). Recent advances indicate that altered thyroid status can affect circulating levels of cytokines secreted from the liver, including fetuin A, fibroblast growth factor 21 (FGF21), and neuregulin