Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA
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Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA
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possible shared mechanistic relationship(s) between DHEA and TL, as described below. The persistence of this finding when examining the interaction with pubertal status and age suggests that DHEA and TL are related, beyond specific developmental contexts
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such as DHEA and its main metabolite, DHEA sulphate (DHEA-S) ( 15 , 23 ). As this brief overview of the literature shows, the role of peripheral kisspeptin concentrations and pubertal development still needs much clarification. In humans, kisspeptin
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Department of Endocrinology, Skaraborg Central Hospital, Skövde, Sweden
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. The median and range values are shown in Supplementary Table 5. In serum, testosterone (mean ± s.d. : 4365 ± 1612 pg/mL) was the major sex steroid, accounting for roughly half of the total amount of the measured sex steroids, followed by DHEA (2130
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(Spearman correlation). CS PregS 17αOH PregS 16αOH DHEAS DHEAS A-3-S AS ES Age 0.07 0.22* 0.24* 0.43*** 0.63*** 0.55*** 0.46*** 0.54*** BMI 0.05 0.19 0.16 0.31** 0.51*** 0.49*** 0
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KORA Study Centre, University Hospital of Augsburg, Augsburg, Augsburg, Germany
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German Centre for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Munich, Germany
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German Heart Centre Munich, Technical University of Munich, Munich, Germany
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
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steroids (cortisol, cortisone, androstenedione, DHEA, and progesterone). For five of the steroids, the LoQ in our laboratory was superior to the manufacturer’s claims (corticosterone, DHEAS, estradiol, 11-deoxycortisosterone, and 17-OHP), while we could not
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
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Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
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Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
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, mean ± SD or median (IQR) Total, n * Type of testosterone status measurement Measurement method Testosterone or DHEA-S, mean ± SD or median (IQR) Amiri M, Andrology , 2019 Adult men from district-13 of Tehran, Iran 1999–2001 42
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA
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Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA
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/mL) AM 92.9 ± 14.7 76.4 ± 13.9 75.7 ± 17.7 65.9 ± 15.5 113.0 ± 23.2 87.0 ± 23.7 DHEAS (ng/mL) PM 47.9 ± 7.6 58.6 ± 12.3 41.0 ± 11.8 43.7 ± 9.5 54.9 ± 9.6 73.4 ± 22.1 Values represent means ± s.e.m. of 7 animals
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.55–1.8 nmol/L, whereas s-androstenedione was 3.5 (IQR 1.0–6.6) and 3.2 (IQR 1.2–6.8), normal range of 2.4–8.9 nmol/L. Mean ICC varied from 0.82 to 0.99. Serum DHEAs had the highest ICC (0.99 (95% CI 0.98–0.99)) corresponding to excellent repeatability between
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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, 17-OHP, androstenedione, and DHEAS ( 15 , 16 ), and inhibin B and AMH ( 17 ). Due to missing reference data in specific age ranges, standardization of hormone concentrations was not possible in all patients < 18 years ( Table 1 ). Biochemical s
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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). All evaluations of puberty in boys were performed by one of 3 male pediatricians. Testicular volume (TV) was measured by palpation to the nearest mL using Prader’s orchidometer. In case of discrepancy between left and right side, the largest