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Suvanjaa Sivalingam Department of Internal Medicine, Hospital of Southern Jutland, Sønderborg, Denmark

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Marianne Thvilum Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark

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Thomas Heiberg Brix Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark
Department of Clinical Research, University of Southern Denmark, Odense M, Denmark

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Frans Brandt Department of Internal Medicine, Hospital of Southern Jutland, Sønderborg, Denmark
Department of Regional Health Research, University of Southern Denmark, Odense M, Denmark

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). The association between GD or TNG and the risk of being born during a certain month of the year was evaluated by Cox regression. Age was chosen as the underlying time variable. To estimate differences in with-in year fluctuations across a 12-month

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Jung Soo Lim Department of Internal Medicine, Institute of Evidence-Based Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Gangwon-do, South Korea

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Seung-Eun Lee Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, South Korea

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Jung Hee Kim Department of Internal Medicine, Seoul National University College of Medicine, Jongno-gu, Seoul, South Korea

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Jae Hyeon Kim Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, South Korea

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The Korean Adrenal Gland and Endocrine Hypertension Study Group, Korean Endocrine Society
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total cohort was as 145 months (95% CI 101.8 – 188.2) and estimated 5-year OS rate was 64.5%. Among the total cohort, there were 174 cases with known ENSAT stage. There were 19 and 29 events in stages 1–3 and stage 4, respectively. Estimated 5-year OS

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Yuan Huang Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

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Yunyun Hu The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Bingshu Bao The Second People’s Hospital, Luqiao, Taizhou, Zhejiang, China

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increase in the obese grade 2 normal visceral fat group ( β : 13.8; 95% CI: 0.10, 27.5, P  = 0.048) showed statistical significance ( Table 3 ). Additionally, the 10-year cardiovascular risk assessment showed the two groups with the highest risk, obese

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Kathrin Zopf Department of Endocrinology, Diabetes and Nutrition, Charité – Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Kathrin R Frey Department of Medicine I, Endocrine and Diabetes Unit, University Hospital, University of Würzburg, Würzburg, Germany

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Tina Kienitz Department of Endocrinology, Diabetes and Nutrition, Charité – Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Manfred Ventz Department of Endocrinology, Diabetes and Nutrition, Charité – Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Britta Bauer Endocrinology in Charlottenburg, Berlin, Germany

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Marcus Quinkler Endocrinology in Charlottenburg, Berlin, Germany

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patient year 1.50 ± 1.43 1.22 ± 1.15 1.58 ± 2.24 % of days with intercurrent illness 2.0 ± 1.8 2.7 ± 3.3 3.2 ± 4.4 No. of pat with AC 4 3 3 No. of AC during study period 6 5 10 AC per 100 patient years 6

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Sigrid Bjerge Gribsholt Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark

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Morten Schmidt Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark

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Eskild Bendix Kristiansen Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark

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Bjørn Richelsen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

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Henrik Toft Sørensen Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

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diabetes, hypertension, and dyslipidemia ( 3 , 4 , 5 , 6 ). Additionally, obesity is recognized as a risk factor in the development of CVD morbidity and mortality ( 4 , 7 , 8 , 9 , 10 , 11 ), owing to inflammation, effects on hemodynamics, and

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Luca Giovanella Clinic for Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland

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Maria Luisa Garo Mathsly Research, Brescia and Vibo Valentia, Italy

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Domenico Albano Nuclear Medicine, University of Brescia and Spedali Civili Brescia, Brescia, Italy

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Rainer Görges Department of Nuclear Medicine, University Hospital of Essen, Essen, Germany

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Luca Ceriani Clinic for Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Faculty of Biomedical Sciences, Institute of Oncology Research, Università della Svizzera Italiana, Bellinzona, Switzerland

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  = 127) (2.38 (95% CI: 1.71; 3.30; test of 𝜗: z = 5.16, P   < 0.001; test of homogeneity: Q = 𝜒 2 (4) = 2.49, P   = 0.65; I 2  = 0.00%) ( Fig. 5 ). Risk ratio of patients with Tg-DT < 1 year showed no significantly changes after subgroup analysis

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Thomas Reinehr Department of Pediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Witten, Germany

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Alberto Sánchez-Guijo Steroid Research & Mass Spectrometry Unit, Division of Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Giessen, Germany

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Nina Lass Department of Pediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Witten, Germany

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Stefan A Wudy Steroid Research & Mass Spectrometry Unit, Division of Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Giessen, Germany

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mellitus, lipid abnormalities and hypertension and may therefore be at particular risk of developing atherosclerotic complications ( 2 , 5 , 6 , 7 , 8 , 9 ). Furthermore, increased androgens are related to polycystic ovarian syndrome (PCOS) in females

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Simon Chang Unit for Thrombosis Research, Institute of Regional Health Research, University of Southern Denmark and Department of Clinical Biochemistry, Hospital of South West Denmark, Esbjerg, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus N, Denmark

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Christian Fynbo Christiansen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark

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Anders Bojesen Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark

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Svend Juul Department of Public Health, Aarhus University, Aarhus C, Denmark

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Anna-Marie B Münster Unit for Thrombosis Research, Institute of Regional Health Research, University of Southern Denmark and Department of Clinical Biochemistry, Hospital of South West Denmark, Esbjerg, Denmark

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Claus H Gravholt Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus N, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus N, Denmark

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supporting the research. Both male hypogonadism and testosterone treatment in men have been associated with an increased risk of thrombotic events ( 2 , 3 , 4 , 5 , 6 , 7 ), and men with KS exhibit an up to six-fold increased risk of venous

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Guang-Ran Yang Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China

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Dongmei Li Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York, USA

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Zidian Xie Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York, USA

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prevalence of DR ( 14 ). Subsequently, 193 T2DM patients aged 50- to 74-year-old were analyzed in the Hoorn study for the risk factors related to DR. The result showed that compared to BMI < 24.5 kg/m 2 DM patients, BMI 25.5–28.4 kg/m 2 DM patients had no

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Kjersti S Bakken Women’s Clinic, Innlandet Hospital Trust, Lillehammer, Norway
Center for International Health, University of Bergen, Bergen, Norway

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Kristina Randjelovic Nermo Center for International Health, University of Bergen, Bergen, Norway
Department of Microbiology, Innlandet Hospital Trust, Lillehammer, Norway

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Bjørn Gunnar Nedrebø Department of Medicine, Haugesund Hospital, Haugesund, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway

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Tim I M Korevaar Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands

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Tor A Strand Center for International Health, University of Bergen, Bergen, Norway
Department of Research, Innlandet Hospital Trust, Lillehammer, Norway

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birth. This variable was missing for 28,337 pregnancies (3.2%). The number of pregnancies each year varied from 54,292 in 2018 to 59,307 in 2010. During 2004–2018, the mean maternal age increased from 29.6 to 30.5 years ( Table 1 ). Figure 1

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