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Department of Gynecology and Obstetrics, Division of Genetic Epidemiology, Vitateq Biotechnology GmbH, University of Duisburg-Essen, D-45122 Essen, Germany
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, and testosterone (ADVIA Centaur, Siemens Healthcare Diagnostics, Eschborn, Germany), androstenedione and sex hormone-binding globulin (SHBG) (Immulite 2000 XPi, Siemens Healthcare Diagnostics), and insulin (Immulite 2000 XPi, Siemens Healthcare
Department of Medicine-Western Health, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia
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Institute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia
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Department of Medicine-Western Health, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia
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hormone-binding globulin (SHBG) was analysed on an Immulite 2000 (Siemens Healthcare Diagnostics Inc.) and luteinizing hormone (LH) on an Architect Analyser (Abbott Diagnostics). Statistical analysis Data were checked for normality and analysed using
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, insulin, total testosterone (TT), Δ4-androstenedione (Δ4A), dehydroepiandrosterone sulfate (DHEA-S) and sex hormone-binding globulin (SHBG) were assessed in the early follicular phase of the menstrual cycle. Homeostatic model assessment-insulin resistance
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Introduction Testosterone is a sex steroid hormone with profound influence on various tissues ( 1 , 2 , 3 ). The precipitous decline in systemic testosterone with age is well described ( 4 ). Additionally, sex hormone-binding globulin (SHBG
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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hypothesized that an increased number of hours of sleep per night would lead to higher concentrations of serum testosterone, and thus, the present study sought to evaluate associations of sex hormone-binding globulin (SHBG), dihydroepiandrosteron-sulfate (DHEAS
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universally present (11) . The levels of sex hormone-binding globulin (SHBG), the primary plasma transport system which controls the availability of androgens, are reduced in women with PCOS leading to an increase in free testosterone levels contributing to
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as previously described ( 26 , 27 ). In addition, circulating concentrations of LH, follicle-stimulating hormone (FSH), sex hormone-binding globulin (SHBG), testosterone, androstenedione (A4), 17α-hydroxyprogesterone (17-OHP), AMH and lipid profile
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Healthcare Diagnostics, UK) with a sensitivity of 0.67 nmol/L, coefficients of intra- and inter-assay variation were lower than 12% and 4%, respectively. Serum thyroid stimulating hormone (TSH), estradiol (E2), prolactin (PRL), sex-hormone binding globulin
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9 BMI, fasting blood glucose, cardiovascular diseases and sex hormone-binding globulin 8 Holmboe et al . ( 9 ) Prospective cohort Denmark 5187 men without diabetes at baseline, including 211 incident T2DM cases and 4976 non
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Introduction Testosterone in serum is primarily bound to proteins with only a minor fraction circulating as free unbound testosterone. The major high-affinity binding protein is sex hormone-binding globulin (SHBG) ( 1 ). Because of the short