Henri Honka
Henri Honka
Turku PET Centre, University of Turku, Turku, Finland
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Jukka Koffert
Jukka Koffert
Turku PET Centre, University of Turku, Turku, Finland
Department of Gastroenterology, Turku University Hospital, Turku, Finland
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Department of Gastroenterology, Turku University Hospital, Turku, Finland
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Saila Kauhanen
Saila Kauhanen
Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland
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Nobuyuki Kudomi
Nobuyuki Kudomi
Faculty of Medicine, Kagawa University, Kagawa, Japan
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Saija Hurme
Saija Hurme
Department of Biostatistics, University of Turku, Turku, Finland
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Andrea Mari
Andrea Mari
Institute of Neuroscience, National Research Council, Padua, Italy
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Andreas Lindqvist
Andreas Lindqvist
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Nils Wierup
Nils Wierup
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Riitta Parkkola
Riitta Parkkola
Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland
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Leif Groop
Leif Groop
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Pirjo Nuutila
Pirjo Nuutila
Turku PET Centre, University of Turku, Turku, Finland
Department of Endocrinology, Turku University Hospital, Turku, Finland
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Department of Endocrinology, Turku University Hospital, Turku, Finland
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and sensitivity, and glycemic control, with no difference between RYGB and VSG groups (Supplementary Table 1, see section on supplementary data given at the end of this article). After surgery, five subjects had normal glucose tolerance and only two
Jiaxi Li
Jiaxi Li
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Pu Huang
Pu Huang
Department of Health Management Center, Changsha Central Hospital, University of South China, Changsha, Hunan, China
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Jing Xiong
Jing Xiong
Department of Endocrinology, Xiangya Third Hospital, Central South University, Changsha, Hunan, China
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Xinyue Liang
Xinyue Liang
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Mei Li
Mei Li
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Hao Ke
Hao Ke
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Chunli Chen
Chunli Chen
Department of Dermatology, Xiangya Third Hospital, Central South University, Changsha, Hunan, China
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Yang Han
Yang Han
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Yanhong Huang
Yanhong Huang
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Yan Zhou
Yan Zhou
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
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Ziqiang Luo
Ziqiang Luo
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China
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Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China
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Dandan Feng
Dandan Feng
Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China
Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China
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Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China
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Chen Chen
Chen Chen
School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Queensland, Australia
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ratio of Ghrelin/LEAP2 may provide another useful index of glycemic control and diabetic progress. Therefore, the purpose of this study is to measure serum ghrelin and LEAP2 levels in T2D patients and to evaluate their correlations with age, gender
Metin Guclu
Metin Guclu
Health Sciences University, Bursa Yuksek Ihtisas Education and Training Hospital, Department of Endocrinology and Metabolism, Bursa, Turkey
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Sinem Kiyici
Sinem Kiyici
Health Sciences University, Bursa Yuksek Ihtisas Education and Training Hospital, Department of Endocrinology and Metabolism, Bursa, Turkey
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Zulfiye Gul
Zulfiye Gul
Department of Pharmacology, Uludag University Medical Faculty, Bursa, Turkey
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Sinan Cavun
Sinan Cavun
Department of Pharmacology, Uludag University Medical Faculty, Bursa, Turkey
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Introduction Excess weight and weight gain are significant problems in the treatment of patients with type 2 diabetes mellitus ( 1 ). Weight reduction is a critical part of type 2 diabetic patients’ management to obtain better glycemic control
Lars Peter Sørensen
Lars Peter Sørensen
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Tina Parkner
Tina Parkner
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Esben Søndergaard
Esben Søndergaard
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Bo Martin Bibby
Bo Martin Bibby
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Holger Jon Møller
Holger Jon Møller
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Søren Nielsen
Søren Nielsen
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) . Interestingly, in our study including subjects with NGT, IGT, and T2DM, sCD163 as well as TNFα, IL6, and CRP concentrations increased with deteriorating glycemic control even though the groups were BMI matched (BMI ∼30 kg/m 2 ) (24) . To the extent sCD163
Emanuela Zaharieva
Emanuela Zaharieva
Department of Internal Medicine, University Hospital Alexandrovska, Clinic of Endocrinology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Zdravko Kamenov
Zdravko Kamenov
Department of Internal Medicine, University Hospital Alexandrovska, Clinic of Endocrinology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Tsvetelina Velikova
Tsvetelina Velikova
Department of Clinical Immunology, University Hospital St. Ivan Rilski, Laboratory of Clinical Immunology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Adelina Tsakova
Adelina Tsakova
Department of Clinical Laboratory, University Hospital Alexandrovska, Central Clinical Laboratory, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Yosif El-Darawish
Yosif El-Darawish
Laboratory of Tumor Immunology and Cell Therapy, Hyogo College of Medicine, Hyogo, Japan
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Haruki Okamura
Haruki Okamura
Laboratory of Tumor Immunology and Cell Therapy, Hyogo College of Medicine, Hyogo, Japan
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), considered by many an indistinguishable part of type 1 diabetes (T1D) ( 10 , 11 , 60 ), usually present with a better metabolic profile and inflammatory markers than T2D, even though optimal glycemic control is usually harder to achieve ( 12 ). Like other
Xiuzhen Zhang
Xiuzhen Zhang
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Dan Xu
Dan Xu
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Ping Xu
Ping Xu
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Shufen Yang
Shufen Yang
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Qingmei Zhang
Qingmei Zhang
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Yan Wu
Yan Wu
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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Fengyi Yuan
Fengyi Yuan
Department of Endocrinology and Metabolism, Shenzhen People’s hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China
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atherosclerosis in T1DM patients, which was primarily ascribed to the reduction in hemoglobin A1c (HbA1c) level ( 5 ). As the standard metric of glycemic control, the HbA1c level is ideally maintained as close to normal as possible for the purpose of reducing the
David Q Pham
David Q Pham
Western University of Health Sciences, College of Pharmacy, Pomona, California, USA
Mary & Dick Allen Diabetes Center at Hoag Hospital, Newport Beach, California, USA
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Mary & Dick Allen Diabetes Center at Hoag Hospital, Newport Beach, California, USA
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Ashley Thorsell
Ashley Thorsell
Sansum Diabetes Research Institute, Santa Barbara, California, USA
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Kristin Castorino
Kristin Castorino
Sansum Diabetes Research Institute, Santa Barbara, California, USA
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Brandon Cobb
Brandon Cobb
Sansum Diabetes Research Institute, Santa Barbara, California, USA
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hyperglycemia in third trimester, reduced LGA, less NICU admissions and less neonatal hypoglycemia 3. Feig et al. Diabetes Care (2018) ( 11 ) Prespecified analysis of secondary outcome measure Compare pumps vs MDI outcomes including glycemic control
Henry Zelada
Henry Zelada
Division of Endocrinology, Diabetes and Metabolism, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA
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M Citlalli Perez-Guzman
M Citlalli Perez-Guzman
Internal Medicine Division of Endocrinology, Centro Médico ABC, Mexico City, Mexico
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Daniel R Chernavvsky
Daniel R Chernavvsky
Center for Diabetes Technology, University of Virginia, Charlottesville, Virginia, USA
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Rodolfo J Galindo
Rodolfo J Galindo
Division of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine. Miami, Florida, USA
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Introduction Evolution of glycemic control in the hospital The management of dysglycemia in the hospital has undergone a significant evolution over the last 30 years, with changes in glucose targets, advances in technology, and increased
Annieke C G van Baar
Annieke C G van Baar
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands
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Andrei Prodan
Andrei Prodan
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
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Camilla D Wahlgren
Camilla D Wahlgren
Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
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Steen S Poulsen
Steen S Poulsen
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Filip K Knop
Filip K Knop
Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Albert K Groen
Albert K Groen
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Laboratory Medicine, University of Groningen, University Medical Center, Groningen, the Netherlands
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Department of Laboratory Medicine, University of Groningen, University Medical Center, Groningen, the Netherlands
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Jacques J Bergman
Jacques J Bergman
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands
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Max Nieuwdorp
Max Nieuwdorp
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Internal Medicine, VUMC Free University, Amsterdam, the Netherlands
Wallenberg Laboratory, Sahlgrenska Hospital, University of Gothenburg, Gothenburg, Sweden
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Department of Internal Medicine, VUMC Free University, Amsterdam, the Netherlands
Wallenberg Laboratory, Sahlgrenska Hospital, University of Gothenburg, Gothenburg, Sweden
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Evgeni Levin
Evgeni Levin
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Horaizon BV, Delft, the Netherlands
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Horaizon BV, Delft, the Netherlands
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parameters in MetS (links in Fig. 4 ). L cell density correlated strongest with SDMA. This metabolite was reported to decrease in subjects with poor glycemic control ( 18 ). In our study, we found a positive correlation between SDMA and duodenal L cell
Jared G Friedman
Jared G Friedman
Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
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Kasey Coyne
Kasey Coyne
Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
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Grazia Aleppo
Grazia Aleppo
Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
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Emily D Szmuilowicz
Emily D Szmuilowicz
Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
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based upon intracellular glycation of hemoglobin molecules within red blood cells, any pathophysiological state that alters red blood cell lifespan can make HbA1c less reliable as a measure of glycemic control. Conditions that alter red blood cell
