Laboratory for Anthropology and Skeletal Biology, Institute of Anatomy, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Search for other papers by Petar Milovanovic in
Google Scholar
PubMed
Search for other papers by Björn Busse in
Google Scholar
PubMed
renewal drastically declines ( 15 , 16 ). The latter might contribute to increased bone fragility and, subsequently, fracture risk increases underpinning major problems in the elderly population ( 17 ). In the year 2000 alone, 9 million osteoporotic
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Rong Xu in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Difei Lian in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Yan Xie in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Lin Mu in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Yali Wu in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Zhilei Chen in
Google Scholar
PubMed
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
Search for other papers by Baoyu Zhang in
Google Scholar
PubMed
Introduction Osteoporosis (OP) is a metabolic bone disease characterized by reduced bone mineral density (BMD) and bone mass and destruction of bone microarchitecture, leading to increased bone fragility and increased risk of fracture ( 1
Search for other papers by Imane Benabbad in
Google Scholar
PubMed
Search for other papers by Myriam Rosilio in
Google Scholar
PubMed
Search for other papers by Maité Tauber in
Google Scholar
PubMed
Search for other papers by Emmanuel Paris in
Google Scholar
PubMed
Search for other papers by Anne Paulsen in
Google Scholar
PubMed
Search for other papers by Lovisa Berggren in
Google Scholar
PubMed
Search for other papers by Hiren Patel in
Google Scholar
PubMed
Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Robert-Debré, Department of Pediatric Endocrinology and Diabetology, and Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Paris, France
Search for other papers by Jean-Claude Carel in
Google Scholar
PubMed
Search for other papers by the Phoenix Study Group in
Google Scholar
PubMed
deviation ( s.d. ). Mean ( s.d. ) duration of leuprorelin treatment was 20.9 (6.4) months for the safety population. Bone fractures during treatment occurred in seven patients in the GH plus leuprorelin group and in three patients in the GH alone
Department of Endocrinology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
Search for other papers by Unni Syversen in
Google Scholar
PubMed
Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
Search for other papers by Mats Peder Mosti in
Google Scholar
PubMed
Search for other papers by Ida Maria Mynarek in
Google Scholar
PubMed
Search for other papers by Trude Seselie Jahr Vedal in
Google Scholar
PubMed
Department of Gastroenterology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
Search for other papers by Kristin Aasarød in
Google Scholar
PubMed
Search for other papers by Trude Basso in
Google Scholar
PubMed
Search for other papers by Janne E Reseland in
Google Scholar
PubMed
Search for other papers by Per Medbøe Thorsby in
Google Scholar
PubMed
K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Trondheim, Norway
Search for other papers by Bjorn O Asvold in
Google Scholar
PubMed
Search for other papers by Erik Fink Eriksen in
Google Scholar
PubMed
Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
Search for other papers by Astrid Kamilla Stunes in
Google Scholar
PubMed
Introduction Several studies have demonstrated increased fracture risk in both type 1 and 2 diabetes (T1D and T2D). A meta-analysis by Shah et al. ( n = 27,300) showed that subjects with T1D displayed a three-fold higher relative risk for
Search for other papers by Nancy Martini in
Google Scholar
PubMed
Search for other papers by Lucas Streckwall in
Google Scholar
PubMed
Search for other papers by Antonio Desmond McCarthy in
Google Scholar
PubMed
atheromatous lesions and a high thrombotic risk. Taken together, while osteoporosis and osteopenia increase the risk of low-stress or fragility bone fractures ( 3 ), AC loading increases the risk of stroke, dementia, myocardial infarction, heart failure, renal
Department of Nutrition, Institute of Life Sciences, Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil
Department of Nutrition, Faculty of Health and Medical Sciences, University of Surrey, University of Surrey, Guildford, UK
Search for other papers by Marcela Moraes Mendes in
Google Scholar
PubMed
Search for other papers by Patricia Borges Botelho in
Google Scholar
PubMed
Search for other papers by Helena Ribeiro in
Google Scholar
PubMed
-hydroxyvitamin D, musculoskeletal health, skeletal health, and bone health. We have selected studies investigating the effects of vitamin D on bone health, musculoskeletal markers, osteoporosis, fractures, and falls in otherwise healthy individuals. Vitamin
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
Search for other papers by I M A A van Roessel in
Google Scholar
PubMed
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
Search for other papers by J E Gorter in
Google Scholar
PubMed
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
Search for other papers by B Bakker in
Google Scholar
PubMed
Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
Search for other papers by M M van den Heuvel-Eibrink in
Google Scholar
PubMed
Department of Radiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Search for other papers by M H Lequin in
Google Scholar
PubMed
Search for other papers by J van der Lugt in
Google Scholar
PubMed
Search for other papers by L Meijer in
Google Scholar
PubMed
Search for other papers by A Y N Schouten-van Meeteren in
Google Scholar
PubMed
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
Search for other papers by H M van Santen in
Google Scholar
PubMed
Introduction Endocrine complications are common in up to 60% of childhood cancer survivors (CCS) ( 1 ). Deprived bone health, ranging from low bone mineral density (BMD) to bone pain and fractures, is a prevalent late effect, and brain tumor
Search for other papers by Iulia Soare in
Google Scholar
PubMed
Department of Endocrinology, Diabetes and Metabolic diseases, Elias Hospital, Bucharest, Romania
Search for other papers by Anca Sirbu in
Google Scholar
PubMed
Department of Gastroenterology, Fundeni Clinical Institute, Bucharest, Romania
Search for other papers by Mihai Mircea Diculescu in
Google Scholar
PubMed
Department of Gastroenterology, Colentina Hospital, Bucharest, Romania
Search for other papers by Bogdan Radu Mateescu in
Google Scholar
PubMed
Department of Gastroenterology, Elias Hospital, Bucharest, Romania
Search for other papers by Cristian Tieranu in
Google Scholar
PubMed
Department of Endocrinology, Diabetes and Metabolic diseases, Elias Hospital, Bucharest, Romania
Search for other papers by Sorina Martin in
Google Scholar
PubMed
Department of Endocrinology, Diabetes and Metabolic diseases, Elias Hospital, Bucharest, Romania
Search for other papers by Carmen Gabriela Barbu in
Google Scholar
PubMed
Department of Gastroenterology, Elias Hospital, Bucharest, Romania
Search for other papers by Mirela Ionescu in
Google Scholar
PubMed
Department of Endocrinology, Diabetes and Metabolic diseases, Elias Hospital, Bucharest, Romania
Search for other papers by Simona Fica in
Google Scholar
PubMed
osteopenia ranges from 32 to 36% and osteoporosis from 7 to 15% ( 2 ). Fracture risk is higher in these patients than in healthy subjects, according to a recent meta-analysis showing a 32% increased risk, which is consistent with different cohort studies
Search for other papers by Anna Gorbacheva in
Google Scholar
PubMed
Search for other papers by Anna Eremkina in
Google Scholar
PubMed
Search for other papers by Daria Goliusova in
Google Scholar
PubMed
Search for other papers by Julia Krupinova in
Google Scholar
PubMed
Search for other papers by Natalia Mokrysheva in
Google Scholar
PubMed
mineral density (BMD) followed by multiple low-energy fractures. In contrast to sporadic PHPT, bone disorders in patients with PHPT in multiple endocrine neoplasias (PHPT/MEN1) are more severe. The higher severity of bone and mineral disorders in patients
Search for other papers by Silvia Ciancia in
Google Scholar
PubMed
Search for other papers by Vanessa Dubois in
Google Scholar
PubMed
Search for other papers by Martine Cools in
Google Scholar
PubMed
-puberty, with subsequent temporary increased risk of fractures ( 23 ). A higher prevalence of fractures has been reported in males ( 24 ). While serum levels of sex hormones and IGF-1 progressively increase during successive pubertal stages, the concomitant