Nathalie Ly
Nathalie Ly
Department of Endocrinology and Reproductive Medicine, Reference Center for Rare Endocrine Diseases of Growth and Development, Reference Center for Gynecological Rare Diseases, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France
EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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Sophie Dubreuil
Sophie Dubreuil
Department of Endocrinology and Reproductive Medicine, Reference Center for Rare Endocrine Diseases of Growth and Development, Reference Center for Gynecological Rare Diseases, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France
EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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Philippe Touraine
Philippe Touraine
Department of Endocrinology and Reproductive Medicine, Reference Center for Rare Endocrine Diseases of Growth and Development, Reference Center for Gynecological Rare Diseases, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France
EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
Sorbonne University, Paris, France
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EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
Sorbonne University, Paris, France
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and reproductive data of a group of 156 female patients referred to a single tertiary department of Endocrinology and Reproductive Medicine (Pitie-Salpetriere Hospital, Paris, France), presenting with GHD. All patients gave their written informed
Meghnaa Hebbar
Meghnaa Hebbar
College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
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Halimah Khalil
Halimah Khalil
College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
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Nawal Zia
Nawal Zia
College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
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Jameela Sheikh
Jameela Sheikh
College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
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Eka Melson
Eka Melson
University of Leicester, Leicester, United Kingdom
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Meri Davitadze
Meri Davitadze
Clinic NeoLab, Tbilisi, Georgia
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Helena Gleeson
Helena Gleeson
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
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Tejal Lathia
Tejal Lathia
Apollo Hospitals, Mumbai, India
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Chitra Selvan
Chitra Selvan
Department of Endocrinology, M S Ramaiah Medical College, Bengaluru, India
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Punith Kempegowda
Punith Kempegowda
Clinic NeoLab, Tbilisi, Georgia
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
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Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
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PCOS SEva Working Group
PCOS SEva Working Group
PCOS SEva Working Group
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-related bias ( 16 ). Female Sexual Function Index (FSFI) assesses the domains of sexual function: desire, arousal, lubrication, orgasm, satisfaction, and pain and provides a score regarding sexual function. Total score achievable is 36, a lower FSFI score
Jennifer K Y Ko
Jennifer K Y Ko
Department of Obstetrics and Gynecology, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China
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Jinghua Shi
Jinghua Shi
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China
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Raymond H W Li
Raymond H W Li
Department of Obstetrics and Gynecology, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China
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William S B Yeung
William S B Yeung
Department of Obstetrics and Gynecology, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China
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Ernest H Y Ng
Ernest H Y Ng
Department of Obstetrics and Gynecology, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China
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models, vitamin D receptor knockout female mice were unable to reproduce due to defects in uterine development and impaired folliculogenesis ( 6 , 33 ). Conversely, direct injection of 1,25(OH)2D3 into the uterine lumen of female rats increased uterine
Silvia Ciancia
Silvia Ciancia
Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium
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Vanessa Dubois
Vanessa Dubois
Basic and Translational Endocrinology (BaTE), Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
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Martine Cools
Martine Cools
Department of Internal Medicine and Pediatrics, Ghent University, Pediatric Endocrinology Service, Ghent University Hospital, Ghent, Belgium
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the spectrum is broad, most TGD youngsters identify as either trans boys (experiencing a male gender identity although being assigned female at birth, AFAB) or trans girls (experiencing a female gender identity although being assigned male at birth
Ewa Stogowska
Ewa Stogowska
Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, Bialystok, Poland
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Karol Adam Kamiński
Karol Adam Kamiński
Department of Population Medicine and Civilization Diseases Prevention, Medical University of Bialystok, Bialystok, Poland
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Bartosz Ziółko
Bartosz Ziółko
Techmo, Kraków, Poland
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Irina Kowalska
Irina Kowalska
Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, Bialystok, Poland
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adolescence, when the hormonal alternations in both genders cause lowering the male voice by even one octave and the female voice by one-third ( 1 ). Although numerous studies indicate the possible influence of the sex hormones fluctuations on vocal parameters
Christos Tsatsanis
Christos Tsatsanis
Department of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Crete, Greece
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
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Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
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Angel Elenkov
Angel Elenkov
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Irene Leijonhufvud
Irene Leijonhufvud
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Katerina Vaporidi
Katerina Vaporidi
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
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Åsa Tivesten
Åsa Tivesten
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Aleksander Giwercman
Aleksander Giwercman
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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BAFF expression both in cells originating from males and females in murine and human cell culture models, but in male-derived cells, the induction was lower than that observed in female-derived cells, suggesting a contribution of factors other than sex
Helene Bandsholm Leere Tallaksen
Helene Bandsholm Leere Tallaksen
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Emma B Johannsen
Emma B Johannsen
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Jesper Just
Jesper Just
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Mette Hansen Viuff
Mette Hansen Viuff
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark
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Claus H Gravholt
Claus H Gravholt
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Anne Skakkebæk
Anne Skakkebæk
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark
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), Klinefelter syndrome (KS; 47,XXY), and Double Y syndrome (47,XYY) is depicted together with karyotypically normal females (46,XX) and males (46,XY). The X chromosome and Y chromosome are shown in pink and blue color, respectively. (B) The copy number of PAR1
Małgorzata Więcek
Małgorzata Więcek
Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland
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Jakub Gawlik
Jakub Gawlik
Student Scientific Society at the Department of Pathophysiology, Jagiellonian University Medical College, Krakow, Poland
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Zuzanna Nowak
Zuzanna Nowak
Student Scientific Society at the Department of Pathophysiology, Jagiellonian University Medical College, Krakow, Poland
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Aneta Gawlik
Aneta Gawlik
Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland
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Introduction Turner syndrome (TS) is the most common sex chromosomal abnormality found in females, with the prevalence of about 1 in 2000 to 1 in 2500 live female births ( 1 ). It is a result of a partial or complete loss of one of the X
Milou Cecilia Madsen
Milou Cecilia Madsen
Department of Internal Medicine and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
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Martin den Heijer
Martin den Heijer
Department of Internal Medicine and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
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Claudia Pees
Claudia Pees
Walaeus Library, Leiden University Medical Center, Leiden, the Netherlands
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Nienke R Biermasz
Nienke R Biermasz
Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands
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Leontine E H Bakker
Leontine E H Bakker
Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands
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testosterone-dependent group are transgender people looking for masculinization. These people are birth-assigned female but identify as male or non-binary. To induce virilization, testosterone therapy is prescribed. This includes deepening of the voice
Hong Tang
Hong Tang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaomei Jiang
Xiaomei Jiang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Yu Hua
Yu Hua
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Heyue Li
Heyue Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Chunlan Zhu
Chunlan Zhu
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaobai Hao
Xiaobai Hao
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Minhui Yi
Minhui Yi
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Linxia Li
Linxia Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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(NEDD4L), a member of the Nedd4 family, was increased in PCOS mice. Here, we confirmed that NEDD4L facilitates the ferroptosis of GCs. Moreover, NEDD4L facilitates ubiquitination-mediated degradation of GPX4. Methods Animals Adult female C57
