I M A A van Roessel
I M A A van Roessel
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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J P de Graaf
J P de Graaf
Dutch Pituitary Foundation, Nijkerk, The Netherlands
Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
Endo-ERN European Reference Network on Rare endocrine conditions
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Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
Endo-ERN European Reference Network on Rare endocrine conditions
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N R Biermasz
N R Biermasz
Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
Endo-ERN European Reference Network on Rare endocrine conditions
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Endo-ERN European Reference Network on Rare endocrine conditions
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E Charmandari
E Charmandari
Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Aghia Sophia Children's Hospital, Athens, Greece
Division of Endocrinology and Metabolism, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
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Division of Endocrinology and Metabolism, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
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H M van Santen
H M van Santen
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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, including arginine vasopressin deficiency (diabetes insipidus (DI)) with adipsia) ( 6 , 7 , 8 , 9 ). Disturbed hunger and satiety feelings in combination with decreased energy expenditure can result in morbid obesity, with the clinical picture being very
Arno Téblick
Arno Téblick
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Ilse Vanhorebeek
Ilse Vanhorebeek
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Inge Derese
Inge Derese
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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An Jacobs
An Jacobs
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Renata Haghedooren
Renata Haghedooren
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Sofie Maebe
Sofie Maebe
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Gerdien A Zeilmaker-Roest
Gerdien A Zeilmaker-Roest
Department of Neonatal & Pediatric Intensive Care, Division of Pediatric Intensive Care, Erasmus MC – Sophia Children’s Hospital, Rotterdam, the Netherlands
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Enno D Wildschut
Enno D Wildschut
Department of Neonatal & Pediatric Intensive Care, Division of Pediatric Intensive Care, Erasmus MC – Sophia Children’s Hospital, Rotterdam, the Netherlands
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Lies Langouche
Lies Langouche
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Greet Van den Berghe
Greet Van den Berghe
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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of the ACTH precursor, pro-opiomelanocortin (POMC) ( 1 ). Results from our mechanistic animal study suggested that during sepsis-induced critical illness, preserved hypothalamic corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP
Beril Erdem
Beril Erdem
Department of Biology, Faculty of Science, Hacettepe University, Ankara, Turkey
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Angela Schulz
Angela Schulz
Rudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Leipzig, Germany
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Emel Saglar
Emel Saglar
Department of Biology, Faculty of Science, Hacettepe University, Ankara, Turkey
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Ferhat Deniz
Ferhat Deniz
Department of Endocrinology, SBÜ Sultan Abdülhamid Han Teaching Hospital, Istanbul, Turkey
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Torsten Schöneberg
Torsten Schöneberg
Rudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Leipzig, Germany
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Hatice Mergen
Hatice Mergen
Department of Biology, Faculty of Science, Hacettepe University, Ankara, Turkey
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blood electrolyte concentration (hypernatremia), respectively, are capable to sense changes in water balance and serum osmolality. Reduction in blood volume or increase in blood electrolyte concentration induces the release of arginine vasopressin (AVP
Kush Dev Singh Jarial
Kush Dev Singh Jarial
Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Anil Bhansali
Anil Bhansali
Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Vivek Gupta
Vivek Gupta
Department of Radio-diagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Paramjeet Singh
Paramjeet Singh
Department of Radio-diagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Kanchan K Mukherjee
Kanchan K Mukherjee
Department of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Akhilesh Sharma
Akhilesh Sharma
Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Rakesh K Vashishtha
Rakesh K Vashishtha
Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Suja P Sukumar
Suja P Sukumar
Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Naresh Sachdeva
Naresh Sachdeva
Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Rama Walia
Rama Walia
Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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.1440499 13 Katoh K Yoshida M Kobayashi Y Onodera M Kogusa K Obara Y. Responses induced by arginine-vasopressin injection in the plasma concentrations of adrenocorticotropic hormone, cortisol, growth hormone and metabolites around weaning time in goats
S U Jayasinghe
S U Jayasinghe
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S J Torres
S J Torres
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C A Nowson
C A Nowson
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A J Tilbrook
A J Tilbrook
Centre for Physical Activity and Nutrition Research, Livestock and Farming Systems, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Melbourne, Victoria 3125, Australia
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A I Turner
A I Turner
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sequential secretion of corticotrophin-releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus, adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland and glucocorticoids such as cortisol from the adrenal cortex (14, 15
Signe Frøssing
Signe Frøssing
Department of Internal Medicine, Center of Endocrinology and Metabolism, Herlev Gentofte Hospital, Copenhagen, Denmark
Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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Malin Nylander
Malin Nylander
Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
Department of Obstetrics & Gynecology, Herlev Gentofte Hospital, Copenhagen, Denmark
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Department of Obstetrics & Gynecology, Herlev Gentofte Hospital, Copenhagen, Denmark
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Caroline Kistorp
Caroline Kistorp
Department of Internal Medicine, Center of Endocrinology and Metabolism, Herlev Gentofte Hospital, Copenhagen, Denmark
Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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Sven O Skouby
Sven O Skouby
Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
Department of Obstetrics & Gynecology, Herlev Gentofte Hospital, Copenhagen, Denmark
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Department of Obstetrics & Gynecology, Herlev Gentofte Hospital, Copenhagen, Denmark
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Jens Faber
Jens Faber
Department of Internal Medicine, Center of Endocrinology and Metabolism, Herlev Gentofte Hospital, Copenhagen, Denmark
Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark
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.109.909663 12 Asferg CL Andersen UB Linneberg A Goetze JP Jeppesen JL. Copeptin, a surrogate marker for arginine vasopressin secretion, is associated with higher glucose and insulin concentrations but not higher blood pressure in
Xiaonan Guo
Xiaonan Guo
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Wenjing Hu
Wenjing Hu
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Xiaorui Lyu
Xiaorui Lyu
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Hanyuan Xu
Hanyuan Xu
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Huijuan Zhu
Huijuan Zhu
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Hui Pan
Hui Pan
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Linjie Wang
Linjie Wang
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Hongbo Yang
Hongbo Yang
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Fengying Gong
Fengying Gong
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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of arginine and proline metabolism ( 42 , 43 ). Besides, arginine, the component of arginine vasopressin (AVP), plays a pivotal role in regulating blood pressure. It has been demonstrated that abnormal AVP levels could severely promote portal
I M A A van Roessel
I M A A van Roessel
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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J E Gorter
J E Gorter
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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B Bakker
B Bakker
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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M M van den Heuvel-Eibrink
M M van den Heuvel-Eibrink
Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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M H Lequin
M H Lequin
Department of Radiology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Department of Radiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Radiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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J van der Lugt
J van der Lugt
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
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L Meijer
L Meijer
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
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A Y N Schouten-van Meeteren
A Y N Schouten-van Meeteren
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
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H M van Santen
H M van Santen
Department of Pediatric Neuro-oncology, Princess Máxima Center, Heidelberglaan, CS Utrecht, The Netherlands
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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deficiency 27.8% (10/36) 15.9% (10/63) 0.156 LH/FSH deficiency 2.8% (1/36) 3.2% (2/63) 0.912 Arginine vasopressin deficiency with thirst feeling 11.1% (4/36) 6.3% (4/63) 0.457 Arginine vasopressin deficiency without
Milena Kloter
Milena Kloter
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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Claudia Gregoriano
Claudia Gregoriano
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
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Ellen Haag
Ellen Haag
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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Alexander Kutz
Alexander Kutz
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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Beat Mueller
Beat Mueller
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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Philipp Schuetz
Philipp Schuetz
Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland
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Faculty of Medicine, University of Basel, Basel, Switzerland
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blood pressure and tissue perfusion, occurs in sepsis and in septic shock resulting in activation of counteracting mediators ( 13 , 14 ). This includes activation of the arginine vasopressin (AVP) on the hypothalamic–pituitary–adrenal (HPA) axis ( 15
Jorge Gabriel Ruiz-Sánchez
Jorge Gabriel Ruiz-Sánchez
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Hospital Universitario Fundación Jiménez Díaz, Madrid, España
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
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Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
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Alfonso Luis Calle-Pascual
Alfonso Luis Calle-Pascual
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España
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Miguel Ángel Rubio-Herrera
Miguel Ángel Rubio-Herrera
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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María Paz De Miguel Novoa
María Paz De Miguel Novoa
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Emilia Gómez-Hoyos
Emilia Gómez-Hoyos
Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, Valladolid, España
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Isabelle Runkle
Isabelle Runkle
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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levels can be insufficient to compensate for this loss in mineralocorticoid function. UNa+ loss ensues, and marked hypovolemia can develop. As a low ECV stimulates baroreceptor-mediated release of arginine vasopressin (AVP), hyponatremia will follow. HH
