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tear fluid for diagnostic purposes . Annales de Biologie Clinique 1993 51 903 – 910 . 4 Riad Fahmy D Read GF Walker RF Griffiths K . Steroids in saliva for assessing endocrine function . Endocrine Reviews 1982 3 367 – 395 . ( doi
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-to-severe GO ( 21 , 22 , 23 ). Lastly, a second course of ivGC treatment or teleradiotherapy in combination with i.v. or oral steroids may be of benefit in selected patients as a second line of therapy. Nevertheless, studies provide only limited evidence to
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glucocorticoid replacement therapy in AI ( 13 ). Recent data, however, suggest that prednisolone is deleterious for bone mineral density in AI ( 17 , 19 , 33 , 34 ). Few comparative data with hydrocortisone for additional steroid-dependent end points are
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gonadotropins, sex steroids and inhibin B were comparable between PCOS sons (PCOSs) and control sons (Cs) during early infancy, childhood and adulthood. We also obtained similar results in stimulated gonadotropin and sex steroid concentrations. However, AMH
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NUMPEX, Pólo de Xerém, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Corrêa da Costa VM. Thyroid function and type 1 iodothyronine deiodinase activity in pre-pubertal and adult rats: effect of sexual steroids . Journal of Endocrinology 2007 192 121 – 130 . ( doi:10.1677/joe.1.06901 ) 10.1677/joe.1.06901 16
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were advised to avoid smoking, drinking alcohol or coffee for 2 h before sample collection. Steroid-containing skin creams were to be avoided, and patients were advised to wash their hands before collection. Some patients gave their saliva samples while
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA
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hypogonadism, a nearly universal finding in adult men with KS, has been implicated as the underlying pathologic mechanism leading to this increased risk ( 2 ). As an anabolic steroid, testosterone has effects on body composition and mitochondrial metabolism
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Berglund and coworkers, 64/78 women with AIS were on HRT and the median age at first prescription of HRT was 14 years ( 1 ). Sex steroid replacement has traditionally been based on types of oestrogen, but there is increasing interest from user groups in the
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Editorial Adrenocortical carcinoma (ACC) is a rare endocrine neoplasia characterized by an overall dismal prognosis and its clinical manifestations are the consequence of either steroid excess or tumor mass progression ( 1 ). Surgery is the
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The University of Liverpool, Brownlow Hill, Liverpool, UK
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definitive diagnosis of adrenal insufficiency. Referral to endocrinology services is advised in all cases. Patients should be provided with a Steroid Emergency Card, education with regards to ‘sick day rules’, and an hydrocortisone emergency injection