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B Fabre Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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G Maccallini Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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A Oneto Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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D Gonzalez Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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V Hirschler Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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C Aranda Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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G Berg Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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tear fluid for diagnostic purposes . Annales de Biologie Clinique 1993 51 903 – 910 . 4 Riad Fahmy D Read GF Walker RF Griffiths K . Steroids in saliva for assessing endocrine function . Endocrine Reviews 1982 3 367 – 395 . ( doi

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0024
Volume/Issue:
Volume 1: Issue 2
Open access
Jakub Supronik Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland

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Małgorzata Szelachowska Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland

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Adam Kretowski Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland

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-to-severe GO ( 21 , 22 , 23 ). Lastly, a second course of ivGC treatment or teleradiotherapy in combination with i.v. or oral steroids may be of benefit in selected patients as a second line of therapy. Nevertheless, studies provide only limited evidence to

Article Type:
Review Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-22-0303
Volume/Issue:
Volume 11: Issue 12
Open access
Marcus Quinkler Endocrinology in Charlottenburg, Berlin, Germany

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Bertil Ekman Departments of Endocrinology and Medical and Health Sciences, Linköping University, Linköping, Sweden

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Claudio Marelli Shire International GmbH, Zug, Switzerland

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Sharif Uddin Shire, Lexington, Massachusetts, USA

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Pierre Zelissen Department of Internal Medicine and Endocrinology, University Medical Center Utrecht, Utrecht, the Netherlands

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Robert D Murray Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, Leeds, UK

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on behalf of the EU-AIR Investigators
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glucocorticoid replacement therapy in AI ( 13 ). Recent data, however, suggest that prednisolone is deleterious for bone mineral density in AI ( 17 , 19 , 33 , 34 ). Few comparative data with hydrocortisone for additional steroid-dependent end points are

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0081
Volume/Issue:
Volume 6: Issue 1
Open access
Nicolás Crisosto Endocrinology and Metabolism Laboratory, West Division, School of Medicine, University of Chile, Santiago, Chile

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Bárbara Echiburú Endocrinology and Metabolism Laboratory, West Division, School of Medicine, University of Chile, Santiago, Chile

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Manuel Maliqueo Endocrinology and Metabolism Laboratory, West Division, School of Medicine, University of Chile, Santiago, Chile

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Marta Luchsinger Endocrinology and Metabolism Laboratory, West Division, School of Medicine, University of Chile, Santiago, Chile

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Pedro Rojas Laboratory of Animal Physiology and Endocrinology, Faculty of Veterinary Sciences, University of Concepción, Chillán, Chile

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Sergio Recabarren Laboratory of Animal Physiology and Endocrinology, Faculty of Veterinary Sciences, University of Concepción, Chillán, Chile

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Teresa Sir-Petermann Endocrinology and Metabolism Laboratory, West Division, School of Medicine, University of Chile, Santiago, Chile

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gonadotropins, sex steroids and inhibin B were comparable between PCOS sons (PCOSs) and control sons (Cs) during early infancy, childhood and adulthood. We also obtained similar results in stimulated gonadotropin and sex steroid concentrations. However, AMH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0218
Volume/Issue:
Volume 6: Issue 8
Open access
Thiago U Pantaleão Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Andrea C F Ferreira Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
NUMPEX, Pólo de Xerém, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Maria C S Santos Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Álvaro S P Figueiredo Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Ruy A N Louzada Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Doris Rosenthal Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Denise P Carvalho Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Vânia M Corrêa da Costa Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Corrêa da Costa VM. Thyroid function and type 1 iodothyronine deiodinase activity in pre-pubertal and adult rats: effect of sexual steroids . Journal of Endocrinology 2007 192 121 – 130 . ( doi:10.1677/joe.1.06901 ) 10.1677/joe.1.06901 16

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0220
Volume/Issue:
Volume 6: Issue 8
Open access
Ramjan Sanas Mohamed Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK

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Biyaser Abuelgasim Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK

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Sally Barker Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK

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Hemanth Prabhudev Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK

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Niamh M Martin Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK

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Karim Meeran Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK

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Emma L Williams Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK

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Sarah Darch Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK

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Whitlock Matthew Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK

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Tricia Tan Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK

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Florian Wernig Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK

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were advised to avoid smoking, drinking alcohol or coffee for 2 h before sample collection. Steroid-containing skin creams were to be avoided, and patients were advised to wash their hands before collection. Some patients gave their saliva samples while

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-22-0050
Volume/Issue:
Volume 11: Issue 7
Open access
Shanlee M Davis Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

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Rhianna Urban Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

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Angelo D’Alessandro Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA

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Julie A Reisz Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA

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Christine L Chan Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

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Megan Kelsey Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

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Susan Howell Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

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Nicole Tartaglia Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

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Philip Zeitler Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

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Peter Baker II Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

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hypogonadism, a nearly universal finding in adult men with KS, has been implicated as the underlying pathologic mechanism leading to this increased risk ( 2 ). As an anabolic steroid, testosterone has effects on body composition and mitochondrial metabolism

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0523
Volume/Issue:
Volume 12: Issue 5
Open access
Jennifer K Y Ko Department of Women’s Health, University College London Hospital, London, UK

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Thomas F J King Department of Women’s Health, University College London Hospital, London, UK

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Louise Williams Department of Women’s Health, University College London Hospital, London, UK

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Sarah M Creighton Department of Women’s Health, University College London Hospital, London, UK

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Gerard S Conway Department of Women’s Health, University College London Hospital, London, UK

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Berglund and coworkers, 64/78 women with AIS were on HRT and the median age at first prescription of HRT was 14 years ( 1 ). Sex steroid replacement has traditionally been based on types of oestrogen, but there is increasing interest from user groups in the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0083
Volume/Issue:
Volume 6: Issue 6
Open access
Deborah Cosentini Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Salvatore Grisanti Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Alberto Dalla Volta Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Marta Laganà Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Chiara Fiorentini Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

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Paola Perotti Internal Medicine, Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Orbassano, Italy

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Sandra Sigala Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

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Alfredo Berruti Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Editorial Adrenocortical carcinoma (ACC) is a rare endocrine neoplasia characterized by an overall dismal prognosis and its clinical manifestations are the consequence of either steroid excess or tumor mass progression ( 1 ). Surgery is the

Article Type:
Editorial
DOI:
https://doi.org/10.1530/EC-18-0398
Volume/Issue:
Volume 7: Issue 12
Open access
C E Higham Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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A Olsson-Brown The Clatterbridge Cancer Centre, Bebbington, Wirral, UK
The University of Liverpool, Brownlow Hill, Liverpool, UK

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P Carroll Department of Endocrinology, Guy’s & St. Thomas’ NHS Foundation Trust, London, UK

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T Cooksley Department of Acute Medicine, UHSM and Christie Hospital NHS Foundation Trust, Manchester, UK

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J Larkin Skin Unit, Royal Marsden Hospital, London, UK

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P Lorigan Department of Medical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK

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D Morganstein Department of Endocrinology, Chelsea and Westminster Hospital, London, UK

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P J Trainer Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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the Society for Endocrinology Clinical Committee The Society for Endocrinology, Starling House, 1600 Bristol Parkway North, Bristol, UK

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definitive diagnosis of adrenal insufficiency. Referral to endocrinology services is advised in all cases. Patients should be provided with a Steroid Emergency Card, education with regards to ‘sick day rules’, and an hydrocortisone emergency injection

Article Type:
Other
DOI:
https://doi.org/10.1530/EC-18-0068
Volume/Issue:
Volume 7: Issue 7
Open access