Lilit Egshatyan
Lilit Egshatyan
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Daria Kashtanova
Daria Kashtanova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Anna Popenko
Anna Popenko
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Olga Tkacheva
Olga Tkacheva
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Alexander Tyakht
Alexander Tyakht
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Dmitry Alexeev
Dmitry Alexeev
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Natalia Karamnova
Natalia Karamnova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Elena Kostryukova
Elena Kostryukova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Vladislav Babenko
Vladislav Babenko
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Maria Vakhitova
Maria Vakhitova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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Sergey Boytsov
Sergey Boytsov
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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reducing had not been found in patients with T2D; although high Blautia genus abundance was associated with glucose intolerance, even in patients who consumed fewer carbohydrates and fats. There is evidence that reducing the amount of carbohydrates in the
Xiaojie Wang
Xiaojie Wang
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
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Zhiyuan Chen
Zhiyuan Chen
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Ziyi Li
Ziyi Li
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
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Bo Chen
Bo Chen
Department of Endocrinology, Guangdong Second Provincial General Hospital, Guangzhou, China
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Yong Qi
Yong Qi
Department of Orthopedics, Guangdong Second Provincial General Hospital, Guangzhou, China
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Guowei Li
Guowei Li
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Jonathan D Adachi
Jonathan D Adachi
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
Department of Medicine, McMaster University, Hamilton, Canada
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Department of Medicine, McMaster University, Hamilton, Canada
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-adjusted life years loss ( 1 ). However, few studies focused on the prevalence and risk factors of fall among middle-aged and older adults. Therefore, it is urgent to investigate the modifiable risk factors of fall in this population. More and more evidence
Christin Krause
Christin Krause
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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Martina Grohs
Martina Grohs
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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Alexander T El Gammal
Alexander T El Gammal
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Stefan Wolter
Stefan Wolter
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Hendrik Lehnert
Hendrik Lehnert
Medical Department I, University of Lübeck, Lübeck, Germany
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Oliver Mann
Oliver Mann
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Jens Mittag
Jens Mittag
Molecular Endocrinology, Medical Department I, University of Lübeck, Lübeck, Germany
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Henriette Kirchner
Henriette Kirchner
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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transport proteins is less clear ( 11 ). Targeting hepatic TH signaling has been a longterm goal in the field, evidenced by the ample number of TRβ-specific compound such as GC-1, GC-24, KB141, KB2115 or MB07811 ( 12 , 13 , 14 , 15 ). Despite their
Qiuli Liu
Qiuli Liu
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Gang Yuan
Gang Yuan
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Dali Tong
Dali Tong
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Gaolei Liu
Gaolei Liu
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Yuting Yi
Yuting Yi
Geneplus-Beijing Institute, Beijing, People’s Republic of China
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Jun Zhang
Jun Zhang
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Yao Zhang
Yao Zhang
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Lin-ang Wang
Lin-ang Wang
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Luofu Wang
Luofu Wang
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Dianzheng Zhang
Dianzheng Zhang
Department of Bio-Medical Sciences, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA
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Rongrong Chen
Rongrong Chen
Geneplus-Beijing Institute, Beijing, People’s Republic of China
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Yanfang Guan
Yanfang Guan
Geneplus-Beijing Institute, Beijing, People’s Republic of China
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Xin Yi
Xin Yi
Geneplus-Beijing Institute, Beijing, People’s Republic of China
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Weihua Lan
Weihua Lan
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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Jun Jiang
Jun Jiang
Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China
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patients were either diagnosed with VHL disease or showed strong evidence related to this disease. Based on one of the recent review articles ( 2 ), VHL is the only gene in which mutations are known to cause VHL disease and these patients have the
Po-Chung Cheng
Po-Chung Cheng
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan
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Chia-Hung Kao
Chia-Hung Kao
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan
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.0000000000012962 ) 17 Bashshur RL Shannon GW Smith BR Woodward MA . The empirical evidence for the telemedicine intervention in diabetes management . Telemedicine Journal and e-Health 2015 21 321 – 354 . ( https://doi.org/10.1089/tmj.2015
Lachlan Angus
Lachlan Angus
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Shalem Leemaqz
Shalem Leemaqz
Robinson Research Institute, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia
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Olivia Ooi
Olivia Ooi
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Pauline Cundill
Pauline Cundill
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Nicholas Silberstein
Nicholas Silberstein
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Peter Locke
Peter Locke
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Jeffrey D Zajac
Jeffrey D Zajac
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Ada S Cheung
Ada S Cheung
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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acetate and spironolactone, have been shown to lower serum testosterone concentrations if added to oestradiol treatment, there is little evidence to guide the superiority of one anti-androgen over another ( 6 ). Both cyproterone acetate and spironolactone
Robert I Menzies
Robert I Menzies
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Xin Zhao
Xin Zhao
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Linda J Mullins
Linda J Mullins
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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John J Mullins
John J Mullins
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Carolynn Cairns
Carolynn Cairns
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Nicola Wrobel
Nicola Wrobel
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Donald R Dunbar
Donald R Dunbar
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Matthew A Bailey
Matthew A Bailey
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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Christopher J Kenyon
Christopher J Kenyon
The University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, Edinburgh, UK
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) were also upregulated. Under normal conditions, excess cholesterol is stored as esters in lipid droplets. As evidenced previously ( 28 , 12 ) and here by oil red O staining, the zona fasciculata cells of ACTH-treated mice are deplete of lipid. A
Maxime Duval
Maxime Duval
Department of Medicine, Clinique Jules Verne, Nantes, France
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Kalyane Bach-Ngohou
Kalyane Bach-Ngohou
Department of Biology, Laboratory of Clinical Biochemistry, CHU Nantes, Nantes, France
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Damien Masson
Damien Masson
Department of Biology, Laboratory of Clinical Biochemistry, CHU Nantes, Nantes, France
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Camille Guimard
Camille Guimard
Department of Emergency Medicine, CHU Nantes, Nantes, France
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Philippe Le Conte
Philippe Le Conte
Department of Emergency Medicine, CHU Nantes, Nantes, France
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David Trewick
David Trewick
Department of Medicine, Clinique Jules Verne, Nantes, France
Department of Emergency Medicine, CHU Nantes, Nantes, France
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Department of Emergency Medicine, CHU Nantes, Nantes, France
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arrhythmias. A significant correlation was found between corrected calcium levels and QTc lengthening. No correlation was however reported between calcium levels and arrhythmias. The authors concluded that the evidence for reversible cardiac dysfunction
Rachel K Rowe
Rachel K Rowe
Phoenix Veterans Affairs Health Care System, Phoenix, Arizona, USA
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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Benjamin M Rumney
Benjamin M Rumney
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
Department of Biology and Biochemistry, University of Bath, UK
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Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
Department of Biology and Biochemistry, University of Bath, UK
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Hazel G May
Hazel G May
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
Department of Biology and Biochemistry, University of Bath, UK
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Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
Department of Biology and Biochemistry, University of Bath, UK
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Paska Permana
Paska Permana
Phoenix Veterans Affairs Health Care System, Phoenix, Arizona, USA
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P David Adelson
P David Adelson
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA
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Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA
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S Mitchell Harman
S Mitchell Harman
Phoenix Veterans Affairs Health Care System, Phoenix, Arizona, USA
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Jonathan Lifshitz
Jonathan Lifshitz
Phoenix Veterans Affairs Health Care System, Phoenix, Arizona, USA
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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Theresa C Thomas
Theresa C Thomas
Phoenix Veterans Affairs Health Care System, Phoenix, Arizona, USA
BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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BARROW Neurological Institute at Phoenix Children’s Hospital, Phoenix, Arizona, USA
Department of Child Health, University of Arizona College of Medicine – Phoenix, Phoenix, Arizona, USA
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(scale bar=50µm; Bar graph represents mean± s.e.m. ). Discussion Experimental diffuse TBI using midline fluid percussion in the rat showed evidence for CORT dysfunction at 54days post-TBI. Plasma CORT levels were significantly decreased
Ann R Webb
Ann R Webb
Department of Earth and Environmental Sciences, University of Manchester, Manchester, UK
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Rehab Alghamdi
Rehab Alghamdi
Department of Earth and Environmental Sciences, University of Manchester, Manchester, UK
Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
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Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
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Richard Kift
Richard Kift
Department of Earth and Environmental Sciences, University of Manchester, Manchester, UK
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Lesley E Rhodes
Lesley E Rhodes
Centre for Dermatology Research, School of Biological Sciences, The University of Manchester and Salford Royal NHS Foundation Trust, Manchester, UK
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body’s vitamin D needs, leading to public health decisions to fortify certain foodstuffs ( 2 ) or to recommend vitamin D supplements for some or all of the population ( 3 , 4 , 5 ) in light of evidence that large proportions of the population have low
