Search Results

You are looking at 121 - 130 of 331 items for :

Clear All
Mabel E Bohórquez Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia

Search for other papers by Mabel E Bohórquez in
Google Scholar
PubMed
Close
,
Ana P Estrada Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia

Search for other papers by Ana P Estrada in
Google Scholar
PubMed
Close
,
Jacob Stultz Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA

Search for other papers by Jacob Stultz in
Google Scholar
PubMed
Close
,
Ruta Sahasrabudhe Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA

Search for other papers by Ruta Sahasrabudhe in
Google Scholar
PubMed
Close
,
John Williamson Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA

Search for other papers by John Williamson in
Google Scholar
PubMed
Close
,
Paul Lott Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA

Search for other papers by Paul Lott in
Google Scholar
PubMed
Close
,
Carlos S Duque Hospital Pablo Tobón Uribe, Medellín, Colombia

Search for other papers by Carlos S Duque in
Google Scholar
PubMed
Close
,
Jorge Donado Hospital Pablo Tobón Uribe, Medellín, Colombia

Search for other papers by Jorge Donado in
Google Scholar
PubMed
Close
,
Gilbert Mateus Hospital Federico Lleras Acosta, Ibagué, Colombia

Search for other papers by Gilbert Mateus in
Google Scholar
PubMed
Close
,
Fernando Bolaños Hospital Hernando Moncaleano Perdomo, Neiva, Colombia

Search for other papers by Fernando Bolaños in
Google Scholar
PubMed
Close
,
Alejandro Vélez Hospital Pablo Tobón Uribe, Medellín, Colombia

Search for other papers by Alejandro Vélez in
Google Scholar
PubMed
Close
,
Magdalena Echeverry Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia

Search for other papers by Magdalena Echeverry in
Google Scholar
PubMed
Close
, and
Luis G Carvajal-Carmona Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA
Fundación de Genética y Genómica, Medellín, Colombia

Search for other papers by Luis G Carvajal-Carmona in
Google Scholar
PubMed
Close

and Chinese populations, we failed to replicate association between HABP2 G534E and TC risk in Hispanic population as well. We, however, acknowledge that our study may have limited power to detect the low-penetrance effect of a variant that is

Open access
Anne Jouinot Department of Medical Oncology, Cochin Hospital, Paris Descartes University, CARPEM, AP-HP, Paris, France
Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

Search for other papers by Anne Jouinot in
Google Scholar
PubMed
Close
,
Bernard Royer CHU Besançon, Clinical Pharmacology and Toxicology Dpt, Besançon cedex, France

Search for other papers by Bernard Royer in
Google Scholar
PubMed
Close
,
Etienne Chatelut Institut Claudius-Regaud, Université de Toulouse, INSERM, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France

Search for other papers by Etienne Chatelut in
Google Scholar
PubMed
Close
,
Sotheara Moeung Institut Claudius-Regaud, Université de Toulouse, INSERM, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France

Search for other papers by Sotheara Moeung in
Google Scholar
PubMed
Close
,
Guillaume Assié Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France

Search for other papers by Guillaume Assié in
Google Scholar
PubMed
Close
,
Audrey Thomas-Schoemann Department of Pharmacy, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France
Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France

Search for other papers by Audrey Thomas-Schoemann in
Google Scholar
PubMed
Close
,
Jérôme Bertherat Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France

Search for other papers by Jérôme Bertherat in
Google Scholar
PubMed
Close
,
François Goldwasser Department of Medical Oncology, Cochin Hospital, Paris Descartes University, CARPEM, AP-HP, Paris, France

Search for other papers by François Goldwasser in
Google Scholar
PubMed
Close
, and
Benoit Blanchet Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France
UMR8638 CNRS, Pharmacy UFR, University of Paris Descartes, PRES sorbonne Paris Cité, Paris, France

Search for other papers by Benoit Blanchet in
Google Scholar
PubMed
Close

sample size, which limits the statistical power and the generalization of the results. Especially, data on etoposide clearance after mitotane discontinuation derived from a single patient. Further studies with larger cohorts are needed to confirm these

Open access
David Koeckerling Medical Sciences Division, University of Oxford, Oxford, UK

Search for other papers by David Koeckerling in
Google Scholar
PubMed
Close
,
Jeremy W Tomlinson Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, UK

Search for other papers by Jeremy W Tomlinson in
Google Scholar
PubMed
Close
, and
Jeremy F Cobbold Oxford Liver Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK

Search for other papers by Jeremy F Cobbold in
Google Scholar
PubMed
Close

limited. Controlled studies with sufficient statistical power to outline exercise programmes or physical activity guidelines tailored to NAFLD patients are lacking ( 64 ). Mechanisms underlying proposed benefits of exercise in NAFLD pertain to improvements

Open access
Ulrik Ø Andersen Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Ulrik Ø Andersen in
Google Scholar
PubMed
Close
,
Dijana Terzic Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Dijana Terzic in
Google Scholar
PubMed
Close
,
Nicolai Jacob Wewer Albrechtsen Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Nicolai Jacob Wewer Albrechtsen in
Google Scholar
PubMed
Close
,
Peter Dall Mark Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Peter Dall Mark in
Google Scholar
PubMed
Close
,
Peter Plomgaard Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Peter Plomgaard in
Google Scholar
PubMed
Close
,
Jens F Rehfeld Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark

Search for other papers by Jens F Rehfeld in
Google Scholar
PubMed
Close
,
Finn Gustafsson Department of Cardiology, Rigshospitalet, Copenhagen, Denmark

Search for other papers by Finn Gustafsson in
Google Scholar
PubMed
Close
, and
Jens P Goetze Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens P Goetze in
Google Scholar
PubMed
Close

://doi.org/10.1016/0014-5793(84)80583-9 ) 18 Power DM Bunnett N Turner AJ Dimaline R . Degradation of endogenous heptadecapeptide gastrin by endopeptidase 24.11 in the pig . American Journal of Physiology 1987 253 G33 – G39 . ( https

Open access
Thozhukat Sathyapalan Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, UK

Search for other papers by Thozhukat Sathyapalan in
Google Scholar
PubMed
Close
,
Anne-Marie Coady Department of Obstetric Ultrasound, Hull and East Yorkshire Women’s and Children’s Hospital, Hull, UK

Search for other papers by Anne-Marie Coady in
Google Scholar
PubMed
Close
,
Eric S Kilpatrick Department of Clinical Biochemistry, Sidra Medical and Research Center, Doha, Qatar

Search for other papers by Eric S Kilpatrick in
Google Scholar
PubMed
Close
, and
Stephen L Atkin Department of Medicine, Weill Cornell Medical College, Doha, Qatar

Search for other papers by Stephen L Atkin in
Google Scholar
PubMed
Close

PCOS ( 11 , 26 ). For 90% power, significance level of 5% and adjusting for a possible 20% dropout rate, 20 subjects were enrolled in each group. Comparisons between both the groups from baseline were carried out using the paired t test for

Open access
Xiaoya Zheng Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Xiaoya Zheng in
Google Scholar
PubMed
Close
,
Heng Xiao Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Heng Xiao in
Google Scholar
PubMed
Close
,
Jian Long Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Jian Long in
Google Scholar
PubMed
Close
,
Qiang Wei Prevention of Disease Department, Chongqing Jiulongpo District Hospital of Traditional Chinese Medicine, Chongqing, China

Search for other papers by Qiang Wei in
Google Scholar
PubMed
Close
,
Liping Liu Department of Ultrasound, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Liping Liu in
Google Scholar
PubMed
Close
,
Liping Zan Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Liping Zan in
Google Scholar
PubMed
Close
, and
Wei Ren Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Wei Ren in
Google Scholar
PubMed
Close

is that the number of patients included is relatively small, and the event rate is accordingly low, thereby limiting the power and reliability of the statistical analysis. It is difficult to draw a statistically significant conclusion if a subgroup

Open access
Magnus F G Grøndahl Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Search for other papers by Magnus F G Grøndahl in
Google Scholar
PubMed
Close
,
Jonatan I Bagger Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

Search for other papers by Jonatan I Bagger in
Google Scholar
PubMed
Close
,
Malte P Suppli Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Search for other papers by Malte P Suppli in
Google Scholar
PubMed
Close
,
Gerrit Van Hall Department of Clinical Biochemistry, Clinical Metabolomics Core Facility, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Gerrit Van Hall in
Google Scholar
PubMed
Close
,
Nicolai J W Albrechtsen Department of Clinical Biochemistry, University Hospital Copenhagen, Bispebjerg, Copenhagen, Denmark

Search for other papers by Nicolai J W Albrechtsen in
Google Scholar
PubMed
Close
,
Jens J Holst Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens J Holst in
Google Scholar
PubMed
Close
,
Tina Vilsbøll Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

Search for other papers by Tina Vilsbøll in
Google Scholar
PubMed
Close
,
Mikkel B Christensen Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Pharmacology, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmark
Copenhagen Center for Translational Research, Copenhagen University Hospital – Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Mikkel B Christensen in
Google Scholar
PubMed
Close
,
Asger B Lund Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Search for other papers by Asger B Lund in
Google Scholar
PubMed
Close
, and
Filip K Knop Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Filip K Knop in
Google Scholar
PubMed
Close

; thus, the multiple comparisons combined with the post hoc nature of the analyses limit the power of our statistical comparisons between groups. Furthermore, the correction for multiple testing increases the risk of type 2 errors. Data should be

Open access
Dirk-Jan van Beek Department of Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Dirk-Jan van Beek in
Google Scholar
PubMed
Close
,
Rachel S van Leeuwaarde Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Rachel S van Leeuwaarde in
Google Scholar
PubMed
Close
,
Carolina R C Pieterman Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Carolina R C Pieterman in
Google Scholar
PubMed
Close
,
Menno R Vriens Department of Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Menno R Vriens in
Google Scholar
PubMed
Close
,
Gerlof D Valk Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
Parelsnoer Institute, Utrecht, The Netherlands

Search for other papers by Gerlof D Valk in
Google Scholar
PubMed
Close
, and
the DutchMEN Study Group
Search for other papers by the DutchMEN Study Group in
Google Scholar
PubMed
Close

can be regarded as a ‘large’ rare disease population. However large, this study population lacked power to detect meaningful differences. In addition, we considered the population as a possible source of selection bias, since our center is a national

Open access
Jairo Arturo Pinzón-Cortés Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Jairo Arturo Pinzón-Cortés in
Google Scholar
PubMed
Close
,
Angelina Perna-Chaux Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Angelina Perna-Chaux in
Google Scholar
PubMed
Close
,
Nicolás Steven Rojas-Villamizar Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Nicolás Steven Rojas-Villamizar in
Google Scholar
PubMed
Close
,
Angélica Díaz-Basabe Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Angélica Díaz-Basabe in
Google Scholar
PubMed
Close
,
Diana Carolina Polanía-Villanueva Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Diana Carolina Polanía-Villanueva in
Google Scholar
PubMed
Close
,
María Fernanda Jácome Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

Search for other papers by María Fernanda Jácome in
Google Scholar
PubMed
Close
,
Carlos Olimpo Mendivil School of Medicine, Universidad de los Andes, Bogotá, Colombia
Endocrinology Section, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia

Search for other papers by Carlos Olimpo Mendivil in
Google Scholar
PubMed
Close
,
Helena Groot Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Helena Groot in
Google Scholar
PubMed
Close
, and
Valeriano López-Segura Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

Search for other papers by Valeriano López-Segura in
Google Scholar
PubMed
Close

catalyzed by enzymes, the methyl group of cytosine can be eliminated by passive processes, such as lack of function of DNMT1, allowing for the loss of methylation through cell divisions ( 28 , 29 ). Given the power of epigenetics to explain metabolic

Open access
Line K Johnson Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Line K Johnson in
Google Scholar
PubMed
Close
,
Kirsten B Holven Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Kirsten B Holven in
Google Scholar
PubMed
Close
,
Njord Nordstrand Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Njord Nordstrand in
Google Scholar
PubMed
Close
,
Jan R Mellembakken Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Jan R Mellembakken in
Google Scholar
PubMed
Close
,
Tom Tanbo Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Tom Tanbo in
Google Scholar
PubMed
Close
, and
Jøran Hjelmesæth Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

Search for other papers by Jøran Hjelmesæth in
Google Scholar
PubMed
Close

attain a power of more than 80% ( α =0.05) to reveal this possible difference. Randomization, allocation and implementation Participants were randomized in blocks of six (three participants to each group). Sealed pre-numbered containers were opened by the

Open access