Alexander V Amram
Alexander V Amram
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Stephen Cutie
Stephen Cutie
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Guo N Huang
Guo N Huang
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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theory for the phylogenetic divergence in cardiac regenerative capacity is the species-dependent onset and intensity of endocrine signaling throughout development ( 2 ). The ability for vertebrates to regenerate damaged heart tissue by replacing lost
Róża Aleksandrowicz
Róża Aleksandrowicz
Department of Prophylaxis of Metabolic Diseases, Bialystok, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
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Marek Strączkowski
Marek Strączkowski
Department of Prophylaxis of Metabolic Diseases, Bialystok, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
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muscle to insulin, defined as insulin resistance (IR), contribute to the development of obesity, type 2 diabetes mellitus (T2DM), and cardiovascular diseases. Skeletal muscle insulin action is decreased in prediabetes and T2DM, but it also may be largely
Yan-yu Zhang
Yan-yu Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Xian Zhang
Xian Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Shao-yang Bu
Shao-yang Bu
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Wei-wei Zhang
Wei-wei Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Tian-xiu Li
Tian-xiu Li
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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De-cai Zheng
De-cai Zheng
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Ze-xiang Huang
Ze-xiang Huang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Qian Wang
Qian Wang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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gonadotropin-releasing hormone (GnRH) and further regulating the gonadotropic hormone (GtHs, including luteinizing hormone and follicle-stimulating hormone) secretion ( 2 ). The GtHs act on the gonads and affect sexual differentiation and gonadal development in
Ying Pei
Ying Pei
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Rui Wang
Rui Wang
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Wanyu Chen
Wanyu Chen
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Shulin Yi
Shulin Yi
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Chen Huang
Chen Huang
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Shaochan Liang
Shaochan Liang
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Hongying Cao
Hongying Cao
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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Yifei Xu
Yifei Xu
Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China
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Bo Tan
Bo Tan
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
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intestinal motility ( 13 ). The gut microbiota plays a pivotal role in ENS development and physiological function ( 14 ). Germ-free mice exhibited abnormalities in ENS morphology and activity ( 15 ). The interaction between gut microbiota and ENS has been
Shiori Minabe
Shiori Minabe
Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Yahaba, Japan
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Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Yahaba, Japan
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Kinuyo Iwata
Kinuyo Iwata
Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
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Youki Watanabe
Youki Watanabe
Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
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Hirotaka Ishii
Hirotaka Ishii
Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
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Hitoshi Ozawa
Hitoshi Ozawa
Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
Faculty of Health Science, Bukkyo University, Kyoto, Japan
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Faculty of Health Science, Bukkyo University, Kyoto, Japan
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( 12 ), and rats ( 13 ). Maternal nutrient restriction impairs the offspring's ovarian function, such as delayed fetal follicular development in sheep ( 14 ), decreased antral follicle numbers in rats and cows ( 15 , 16 , 17 ), and reduced adult
Angelo Maria Patti
Angelo Maria Patti
Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy
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Kalliopi Pafili
Kalliopi Pafili
Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece
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Nikolaos Papanas
Nikolaos Papanas
Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece
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Manfredi Rizzo
Manfredi Rizzo
Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy
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development of gestational diabetes (GDM) cases ( 1 ). Epidemiological evidence has consistently shown that among mothers with prior history of GDM, 30–84% of them had GDM recurrence in subsequent pregnancies ( 2 ), 20–40% developed metabolic syndrome (MetS
Elizabeth Micks
Elizabeth Micks
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Greta B Raglan
Greta B Raglan
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Jay Schulkin
Jay Schulkin
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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these issues (6) . Reducing unmet need for family planning represents one of the most effective strategies for improving maternal health (7) , and progestogens remain one of the most promising avenues for contraceptive research and development. However
Legh Wilkinson
Legh Wilkinson
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Nicolette J D Verhoog
Nicolette J D Verhoog
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Ann Louw
Ann Louw
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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signalling, often resulting in various peripheral effects, one of which is the tissue-specific reductions in the glucocorticoid receptor α (GRα) functional pool. This reduction in the GRα functional pool may ultimately drive the development of acquired GC
Yiqiong Ma
Yiqiong Ma
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Zhaowei Chen
Zhaowei Chen
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Yu Tao
Yu Tao
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Jili Zhu
Jili Zhu
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Hongxia Yang
Hongxia Yang
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Wei Liang
Wei Liang
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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Guohua Ding
Guohua Ding
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China
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progression of DN ( 13 ). Our previous studies confirmed that high levels of glucose cause mitochondrial ROS production and increases the podocyte apoptosis rate ( 14 , 15 ). However, whether mitochondrial dynamics contribute to the development and
Izabelle Lövgren
Izabelle Lövgren
Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
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Azadeh Abravan
Azadeh Abravan
Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK
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Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK
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Abigail Bryce-Atkinson
Abigail Bryce-Atkinson
Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
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Marcel van Herk
Marcel van Herk
Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK
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Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK
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normal growth and development, a deficiency can have significant impacts such as stunted growth, dwarfism, and obesity ( 9 ). Furthermore, TSH deficiency was the second most common endocrinopathy that manifested in 20.5% of patients, followed by ACTH
