Search Results

You are looking at 121 - 130 of 248 items for :

Clear All
Morten Winkler Møller Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

Search for other papers by Morten Winkler Møller in
Google Scholar
PubMed
Close
,
Marianne Skovsager Andersen Clinical Institute, University of Southern Denmark, Odense C, Denmark
Department of Endocrinology, Odense University Hospital, Odense C, Denmark

Search for other papers by Marianne Skovsager Andersen in
Google Scholar
PubMed
Close
,
Christian Bonde Pedersen Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

Search for other papers by Christian Bonde Pedersen in
Google Scholar
PubMed
Close
,
Bjarne Winther Kristensen Clinical Institute, University of Southern Denmark, Odense C, Denmark
Department of Pathology, Odense University Hospital, Odense C, Denmark

Search for other papers by Bjarne Winther Kristensen in
Google Scholar
PubMed
Close
, and
Frantz Rom Poulsen Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

Search for other papers by Frantz Rom Poulsen in
Google Scholar
PubMed
Close

were discussed with senior neurosurgeons. Pituitary function Pituitary hormone evaluation was assessed preoperatively and postoperatively based on clinical biochemical data including the hypothalamic–pituitary–somatotropic axis (s-GH and s-IGF-1

Open access
Lukas Plachy Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Lukas Plachy in
Google Scholar
PubMed
Close
,
Petra Dusatkova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Petra Dusatkova in
Google Scholar
PubMed
Close
,
Klara Maratova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Klara Maratova in
Google Scholar
PubMed
Close
,
Shenali Anne Amaratunga Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Shenali Anne Amaratunga in
Google Scholar
PubMed
Close
,
Dana Zemkova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Dana Zemkova in
Google Scholar
PubMed
Close
,
Vit Neuman Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Vit Neuman in
Google Scholar
PubMed
Close
,
Stanislava Kolouskova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Stanislava Kolouskova in
Google Scholar
PubMed
Close
,
Barbora Obermannova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Barbora Obermannova in
Google Scholar
PubMed
Close
,
Marta Snajderova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Marta Snajderova in
Google Scholar
PubMed
Close
,
Zdenek Sumnik Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Zdenek Sumnik in
Google Scholar
PubMed
Close
,
Jan Lebl Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Jan Lebl in
Google Scholar
PubMed
Close
, and
Stepanka Pruhova Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu, Prague, Czech Republic

Search for other papers by Stepanka Pruhova in
Google Scholar
PubMed
Close

auxological and/or other clinical features suggestive of GHD ( 14 ) and IGF-1 concentration <0 s.d. (reference ranges standardized for age and sex), GHD was confirmed by GH stimulation tests. Two different stimulation tests (clonidine and insulin hypoglycemia

Open access
Giovanni Tulipano Unit of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

Search for other papers by Giovanni Tulipano in
Google Scholar
PubMed
Close

transcription regulators. Glucocorticoids modulate GH secretion by acting at the hypothalamic and pituitary level and can also influence downstream effectors like insulin-like growth factor-1 (IGF-1). For a long time, a model of biphasic dose-dependent effects

Open access
Peter Wolf Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

Search for other papers by Peter Wolf in
Google Scholar
PubMed
Close
,
Yvonne Winhofer Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

Search for other papers by Yvonne Winhofer in
Google Scholar
PubMed
Close
,
Martin Krššák Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

Search for other papers by Martin Krššák in
Google Scholar
PubMed
Close
, and
Michael Krebs Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

Search for other papers by Michael Krebs in
Google Scholar
PubMed
Close

or indirect stimulation of production of insulin-like growth factor1 (IGF-1) are complex. GH is directly acting as a strong promoter in lipolytic signaling ( 65 ). In contrast, GH might also promote lipid synthesis and storage by induction of IGF-1

Open access
Angelica Lindén Hirschberg Division of Obstetrics and Gynaecology, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden
Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.

Search for other papers by Angelica Lindén Hirschberg in
Google Scholar
PubMed
Close

insulin and insulin-like growth factor I (IGF-I) and high levels of growth hormone and IGF-binding protein-1 ( Fig. 1 ) ( 4 , 7 , 8 ). Because IGF-I stimulates the release of both GnRH and LH, a decline in IGF-I activity may, at least in part, explain

Open access
Aleksandra Gilis-Januszewska Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland

Search for other papers by Aleksandra Gilis-Januszewska in
Google Scholar
PubMed
Close
,
Łukasz Kluczyński Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland

Search for other papers by Łukasz Kluczyński in
Google Scholar
PubMed
Close
, and
Alicja Hubalewska-Dydejczyk Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland

Search for other papers by Alicja Hubalewska-Dydejczyk in
Google Scholar
PubMed
Close

pituitary volume) and also ACTH deficiency in 8% of the participants ( 42 ). The same author reported decreased IGF-1 levels in amateur kickboxers; 22% and 9% of them were diagnosed with GH and ACTH deficiency, respectively ( 54 ). In another study

Open access
Nannan Bian Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Nannan Bian in
Google Scholar
PubMed
Close
,
Xiaomeng Sun Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Xiaomeng Sun in
Google Scholar
PubMed
Close
,
Biao Zhou Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China

Search for other papers by Biao Zhou in
Google Scholar
PubMed
Close
,
Lin Zhang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Lin Zhang in
Google Scholar
PubMed
Close
,
Qiu Wang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Qiu Wang in
Google Scholar
PubMed
Close
,
Yu An Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Yu An in
Google Scholar
PubMed
Close
,
Xiaohui Li Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Xiaohui Li in
Google Scholar
PubMed
Close
,
Yinhui Li Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Yinhui Li in
Google Scholar
PubMed
Close
,
Jia Liu Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Jia Liu in
Google Scholar
PubMed
Close
,
Hua Meng Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China

Search for other papers by Hua Meng in
Google Scholar
PubMed
Close
, and
Guang Wang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

Search for other papers by Guang Wang in
Google Scholar
PubMed
Close

). Crosstalk between cell-surface GPCRs and receptor tyrosine kinases (RTKs) is a pervasive phenomenon ( 38 ). The insulin-like growth factor 1 receptor (IGF1R) is an RTK shown to have crosstalk with TSHR in brow fat and orbital fat of patients with thyroid

Open access
Maximilian Bielohuby Sanofi-Aventis Deutschland GmbH, R&D, Industriepark Höchst, Frankfurt, Germany

Search for other papers by Maximilian Bielohuby in
Google Scholar
PubMed
Close
,
Martin Bidlingmaier Endocrine Research Laboratories, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany

Search for other papers by Martin Bidlingmaier in
Google Scholar
PubMed
Close
, and
Uwe Schwahn Sanofi-Aventis Deutschland GmbH, R&D, Industriepark Höchst, Frankfurt, Germany

Search for other papers by Uwe Schwahn in
Google Scholar
PubMed
Close

other metabolic hormones. However, there are also examples from relatively stable circulating parameters in rodents, such as IGF-I, which seems to be only marginally affected by these variables (( 40 ) and unpublished observations). Unfortunately, there

Open access
Brenda Anguiano Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

Search for other papers by Brenda Anguiano in
Google Scholar
PubMed
Close
,
Carlos Montes de Oca Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

Search for other papers by Carlos Montes de Oca in
Google Scholar
PubMed
Close
,
Evangelina Delgado-González Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

Search for other papers by Evangelina Delgado-González in
Google Scholar
PubMed
Close
, and
Carmen Aceves Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

Search for other papers by Carmen Aceves in
Google Scholar
PubMed
Close

-adrenergic receptor levels. (70) 0.1 LNCaP Biphasic response. Increases the specific binding to GH and GH receptor expression within the first 24 h and reduces the binding at 72 h. (63) 0.1 LNCaP Increases gene expression of IGF-1, IGF

Open access
Antonia Ertelt Equine Clinic, Free University of Berlin, Berlin, Germany

Search for other papers by Antonia Ertelt in
Google Scholar
PubMed
Close
,
Ann-Kristin Barton Equine Clinic, Free University of Berlin, Berlin, Germany

Search for other papers by Ann-Kristin Barton in
Google Scholar
PubMed
Close
,
Robert R Schmitz Equine Clinic, Free University of Berlin, Berlin, Germany

Search for other papers by Robert R Schmitz in
Google Scholar
PubMed
Close
, and
Heidrun Gehlen Equine Clinic, Free University of Berlin, Berlin, Germany

Search for other papers by Heidrun Gehlen in
Google Scholar
PubMed
Close

caused primarily by activation of ETRA located in smooth muscle of blood vessels (122) . In addition, insulin-like growth factor 1 (IGF1), a polypeptide with close structural homology to insulin and well-known effects in terms of activating cell

Open access