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Helga Schultz, Svend Aage Engelholm, Eva Harder, Ulrik Pedersen-Bjergaard and Peter Lommer Kristensen

(MSCC) and brain tumours. Diabetes mellitus (DM) is a well-known metabolic side effect from treatment with glucocorticoids. The diabetogenic effect is mainly a result of insulin resistance in muscle and fatty tissue, increased production of glucose from

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Aneta Gawlik, Michael Shmoish, Michaela F Hartmann, Stefan A Wudy, Zbigniew Olczak, Katarzyna Gruszczynska and Ze’ev Hochberg

.5) were calculated as indices of insulin resistance. Cortisol was measured in the morning (08:00 h) and midnight using chemiluminescent immunoassay by Immulite 2000 analyzer (DPC, USA). Serum concentrations of fT4 and TSH were measured with a

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Ling-Jun Li, Izzuddin M Aris, Lin Lin Su, Yap Seng Chong, Tien Yin Wong, Kok Hian Tan and Jie Jin Wang

, 3 ). The diagnosis of GDM identifies women with insulin resistance (targeted cell resistance to the activity of insulin) and/or β-cell dysfunction (insufficient secretion of insulin by the pancreatic β-cells to compensate for peripheral insulin

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M A Webb, H Mani, S J Robertson, H L Waller, D R Webb, C L Edwardson, D H Bodicoat, T Yates, K Khunti and M J Davies

to insulin resistance ( 9 , 10 ). Indeed experimental studies in healthy subjects have demonstrated that IL6 injections increase blood glucose without any changes in C-peptide levels, suggesting that IL6 directly reduces insulin sensitivity ( 11

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Magnolia Ariza-Nieto, Joshua B Alley, Sanjay Samy, Laura Fitzgerald, Francoise Vermeylen, Michael L Shuler and José O Alemán

, fasting plasma insulin; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, insulin resistance by homeostatic model assessment; LDL-C, low-density lipoprotein cholesterol; tAdp, total fasting

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Aline Stangherlin Martins, Ann Kristine Jansen, Luiz Oswaldo Carneiro Rodrigues, Camila Maria Matos, Marcio Leandro Ribeiro Souza, Juliana Ferreira de Souza, Maria de Fátima Haueisen Sander Diniz, Sandhi Maria Barreto, Leonardo Mauricio Diniz, Nilton Alves de Rezende and Vincent Michael Riccardi

previous studies (6, 8) . Both type 1 and type 2 DM contribute to development of VD (12) . Type 1 DM is associated with an inadequate availability of insulin and usually manifests in childhood, whereas type 2 DM is related to insulin resistance and

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Ling Zhou, Zhexin Ni, Wen Cheng, Jin Yu, Shuai Sun, Dongxia Zhai, Chaoqin Yu and Zailong Cai

Introduction Polycystic ovary syndrome (PCOS) is characterised by persistent anovulation, hyperandrogenism and insulin resistance (IR), involving a group of reproductive, endocrine and metabolic disorders. The pathophysiology of PCOS is

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Katarzyna Wyskida, Grzegorz Franik, Tomasz Wikarek, Aleksander Owczarek, Alham Delroba, Jerzy Chudek, Jerzy Sikora and Magdalena Olszanecka-Glinianowicz

calculated according to the standard formula: HOMA-IR = fasting serum insulin (μIU/mL) × fasting glucose (mg/dL)/405. The cutoff value for insulin resistance was ≥2.5. The ELISA method was also used for measurements of plasma leptin (TECOmedical AG, Sissach

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Julia Kubiak, Per Medbøe Thorsby, Elena Kamycheva and Rolf Jorde

parameters, while the rest showed no effects or even adverse outcomes ( 14 ). In a meta-analysis by Poolsup et al . including 10 trials, no effect of vitamin D on insulin resistance was found in subjects with pre-diabetes ( 15 ). And finally, in a study from

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A V Dreval, I V Trigolosova, I V Misnikova, Y A Kovalyova, R S Tishenina, I A Barsukov, A V Vinogradova and B H R Wolffenbuttel

to IGF1, a recent paper reported that higher IGF1 levels were associated with more severe insulin resistance and hyperglycaemia (12) . In accordance with the data of Colao et al . (14) , the presence of DM was associated with a higher age and